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排序方式: 共有447条查询结果,搜索用时 15 毫秒
41.
目的:评价鼻内窥镜下筛窦切除术治疗视神经炎的疗效。方法:对4例视神经炎患者行鼻内窥镜下筛窦切除术。结果:显效2例,有效2例。鼻塞,眼胀,头痛症状缓解。结论:对合并有筛窦炎的视神经炎患者,在保守治疗无效或治疗后有反复时,及时行鼻内窥镜下筛窦切除术有效率高,且安全、可靠。 相似文献
42.
目的 探讨应用无创性动态阴茎海绵体测压 (VISER)在勃起功能障碍 (ED)诊断中的价值。 方法 对 5 3例ED患者的PGE1阴茎海绵体内注射试验、VISER及彩色双功能超声检查结果进行对比分析。 结果 PorstⅢ级者 4 3例 ,平均海绵体压力和压力指数分别为 14 4 .2 9mmHg(1mmHg=0 .133kPa)和 1.2 4。 4 2例血管功能正常 ,1例为静脉性ED ;PorstⅡ级者 10例 ,平均海绵体压力和压力指数为 87.76mmHg和 0 .81,两组间比较差别有显著性意义 (P <0 .0 5 ) ;PorstⅡ级者中动脉性ED2例 ,静脉性ED8例 ,两组间海绵体压力比较差别有显著性意义 (P <0 .0 5 )。 结论 VIS ER是一种有效的无创性诊断ED的方法 ,对动脉性及静脉性ED的鉴别亦有一定价值。 相似文献
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R Cruz-Aguado CI Fernández-Verdecia CM Díaz-Suárez O González-Monzón I Antúnez-Potashkina and J Bergado-Rosado 《Fundamental & clinical pharmacology》1998,12(5):538-545
Summary— Neurotrophins, like the nerve growth factor (NGF), trigger a variety of biological effects in their targets. Stimulating effects on antioxidant defenses have been postulated to underlie neurotrophic influence on neuron survival and maintenance. To test whether NGF is capable of inducing changes in glutathione-related enzymes in the aged cognitively impaired brain, glutathione reductase (GRD), glutathione S-transferase (GST) and total glutathione peroxidase (GPX) activities were measured in the striatum, septum, hippocampus and frontal cortex of four Sprague-Dawley rat groups: young (2 months old), aged (20 months old) untreated, aged cytochrome c-treated, and aged NGF-treated (icv delivery, 34 4mUg during 28 days). All the aged rats utilized in the study were memory impaired according to their performance in the Morris water maze test. These aged rats showed increases in the activities of septal and hippocampal GST, as well as, in the hippocampal, striatal and cortical GPX. These increases could be interpreted as compensatory responses to cope with the oxidative damage that has been accumulated by the aged brain. The increases in hippocampal and cortical GPX activity were attenuated by NGF treatment, whereas the neurotrophin induced an increase in GRD activity in the striatum of aged rats. These results point out GRD and GPX as possible targets of the neurotrophic effects. 相似文献
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Ann Gardulf RN PhD Hjordis Bjorvell RN Vagn Andersen MD Janne Bjorkander MD Diddi Ericson RN Stig S Frøland MD Rolf Gustafson MD PhD Lennart Hammarstrom MD Tuna Nystrom RN Bjørn Søeberg MD CI Edvard Smith MD 《Journal of advanced nursing》1995,21(5):917-927
Primary antibody deficiencies are chronic conditions and the patients usually need lifelong replacement therapy with gammaglobulin to prevent or reduce infections It has been shown that the gammaglobulm can be given safely as subcutaneous infusions, instead of intramuscular injections or intravenous infusions The major aim of this multi-centre study was to investigate the perceptions of the subcutaneous method among patients using it, both in hospital settings and as self-infusions at home The study included 152 patients 89 women, 63 men, mean age 44 years (range 18-76) Data were collected by using questionnaires The patients were found to have a strongly positive attitude towards receiving the replacement therapy as subcutaneous infusions, perceived the method as effective in preventing infections and wished to retain the treatment However, the younger patients found the subcutaneous infusions more uncomfortable and were less determined to continue with the therapy as compared with the older individuals The responsibility for self-infusions at home was accepted by the patients, leading to an increased independence from the health care personnel and to a feeling of flexibility and freedom As these patients have a chronic disease and are in need of lifelong treatment, it is important to discuss the development of structured education and training programmes in which special emphasis is placed on the support of the younger patients It is suggested that Orem's nursing model of self-care may serve as a conceptual framework for nurses working in this specific area of nursing care 相似文献
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目的:通过观察转录因子FoxO3a在小鼠牙胚发育中的表达特点及分布情况,探讨其在小鼠牙胚发育过程中的作用。方法取出生0 d和3 d的昆明小鼠各3只,处死解剖下颌骨,放于新鲜配置的10%中性甲醛溶液中固定过夜,制备小鼠牙胚0d和3d的组织标本,常规石蜡包埋,近远中向5μm连续切片,采用免疫组化方法观察检测FoxO3 a在小鼠不同时期的牙胚表达情况和分布情况,并对结果进行分析。结果 FoxO3 a在小鼠不同时期的牙胚发育中的分布存在差异,FoxO3a在0d小鼠牙胚中,成牙本质细胞成阴性表达,在3d小鼠牙胚中成牙本质细胞成阳性表达。结论观察FoxO3a在小鼠牙胚发育过程中的表达以及表达的变化,提示FoxO3a可能参与牙本质的形成和矿化。 相似文献
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目的随访阻塞性睡眠呼吸暂停综合征(OSAS)与高脂血症的关系。方法对1868人进行前瞻性随访,通过家访式调查,随访期间每年进行1次体检,检查血压、血脂、血糖、心电图及X线胸片等,随访时间为20年。结果确诊OSAS者598/1868(32.0%),男496例(82.9%),女102例(17.1%);无OSAS者(对照组)1270/1868(68.0%)。随访终点OSAS组高脂血症529例,对照组396例(P<0.01)。结论 OSAS患者发生高脂血症可能性较一般人群高,考虑OSAS与高脂血症发生存在相关性。提示OSAS可能是高脂血症的独立危险因素。引起高脂血症的机制可能与OSAS导致食欲增加、活动减少、肥胖等有关。 相似文献
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