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51.
Alberto Berardi Cecilia Rossi Maria Letizia Bacchi Reggiani Annalisa Bastelli Maria Grazia Capretti Claudio Chiossi 《The journal of maternal-fetal & neonatal medicine》2017,30(14):1739-1744
Introduction: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking.Materials and methods: This was a 3-month retrospective area-based study including all regional deliveries ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated.Results: Among 7133 women, 259 (3.6%) were preterm (35–36 weeks' gestation). Full-term women were 6874, and 876 (12.7%) had at least 1?RF. Most women (6495) had prenatal screening and 21.4% (1390) were GBS positive.IAP was given to 2369 (33.2%) women (preterm, n?=?166; full term, n?=?2203). Compared to full-term, preterm women were less likely to receive IAP when indicated (73.2% versus 90.3%, p?0.01). Full-term women represented the largest area under the curve (AUC, 0.87). PROM showed the highest sensitivity (98.6%), but the lowest specificity (6.9%) and AUC (0.53).Conclusions: Large-scale prenatal screening and IAP are feasible. Women delivering preterm are less likely to receive IAP when indicated. Most unnecessary antibiotics are given in cases of PROM. 相似文献
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Iria Neri M.D. Arianna Dondi M.D. Lorenza Ricci M.D. Annalisa Patrizi M.D. 《Pediatric dermatology》2014,31(3):e73-e75
Baboon syndrome is a combination of diffuse symmetrical erythema on the major flexural areas and V‐shaped erythema on both upper anteromedial thighs. Infectious agents have been described as possible triggers. We describe for the first time baboon syndrome in a child induced by a coinfection with Epstein‐Barr virus and cytomegalovirus. 相似文献
54.
Annalisa Rizzo Maddalena Mutinati Massimo Spedicato Giuseppe Minoia Carmelinda Trisolini Felicita Jirillo 《Immunopharmacology and immunotoxicology》2013,35(4):741-746
Reactive Oxygen Species (ROS) are produced during oxidative metabolism, and regulate many biological processes. The acute inflammation characterizing parturition induces many physiological changes. Among them, there is evidence that ROS affect the synthesis of many factors involved in parturition. Our study aims to determine serum levels of ROS in periparturient ewes, as well as to establish a value of reference of their physiological concentration.ROS determination was performed on blood collected every 12 hours in periparturient twin pregnant ewes. Our results will show a significant increase in ROS concentrations from the beginning to the end of the experiment. This increase may be due to the inflammatory process establishing during parturition. 相似文献
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G. Marruchella C. Ligios M. Baffoni M. G. Cancedda F. Demontis G. Donatucci R. Chiocchetti P. Clavenzani G. Lalatta-Costerbosa G. Di Guardo 《Archives of virology》2009,154(4):709-714
Ileal Peyer’s patches (PPs) are involved early during sheep scrapie infection. This study qualitatively and semi-quantitatively
evaluated ileal tract and PP innervation in 29 Sarda ovines of different age, PrP genotype and scrapie status. A prominent
network of fibres was detected within PPs, mainly located in interfollicular lymphoid and stromal components. Intrafollicular
fibres were rarely observed, with no apparent differences between scrapie-free and scrapie-affected animals, or among ovines
carrying different PrP genotypes. In adult sheep, independent of their scrapie status, nerve fibres could be detected infrequently,
close to the follicle-associated epithelium. Fibres were also detected within newly formed follicles and intrafollicular microgranulomas. 相似文献
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