全文获取类型
| 收费全文 | 81459篇 |
| 免费 | 4650篇 |
| 国内免费 | 250篇 |
专业分类
| 耳鼻咽喉 | 934篇 |
| 儿科学 | 2049篇 |
| 妇产科学 | 1083篇 |
| 基础医学 | 10810篇 |
| 口腔科学 | 860篇 |
| 临床医学 | 8508篇 |
| 内科学 | 17235篇 |
| 皮肤病学 | 892篇 |
| 神经病学 | 7879篇 |
| 特种医学 | 3083篇 |
| 外科学 | 12862篇 |
| 综合类 | 892篇 |
| 一般理论 | 91篇 |
| 预防医学 | 5989篇 |
| 眼科学 | 1973篇 |
| 药学 | 5419篇 |
| 9篇 | |
| 中国医学 | 94篇 |
| 肿瘤学 | 5697篇 |
出版年
| 2024年 | 254篇 |
| 2023年 | 742篇 |
| 2022年 | 1072篇 |
| 2021年 | 2489篇 |
| 2020年 | 1461篇 |
| 2019年 | 2338篇 |
| 2018年 | 2548篇 |
| 2017年 | 1812篇 |
| 2016年 | 1899篇 |
| 2015年 | 2216篇 |
| 2014年 | 3210篇 |
| 2013年 | 4063篇 |
| 2012年 | 6512篇 |
| 2011年 | 6755篇 |
| 2010年 | 3693篇 |
| 2009年 | 3237篇 |
| 2008年 | 5397篇 |
| 2007年 | 5593篇 |
| 2006年 | 5180篇 |
| 2005年 | 5136篇 |
| 2004年 | 4635篇 |
| 2003年 | 4248篇 |
| 2002年 | 3858篇 |
| 2001年 | 598篇 |
| 2000年 | 398篇 |
| 1999年 | 568篇 |
| 1998年 | 788篇 |
| 1997年 | 588篇 |
| 1996年 | 482篇 |
| 1995年 | 425篇 |
| 1994年 | 399篇 |
| 1993年 | 396篇 |
| 1992年 | 251篇 |
| 1991年 | 199篇 |
| 1990年 | 178篇 |
| 1989年 | 164篇 |
| 1988年 | 169篇 |
| 1987年 | 131篇 |
| 1986年 | 139篇 |
| 1985年 | 146篇 |
| 1984年 | 184篇 |
| 1983年 | 150篇 |
| 1982年 | 238篇 |
| 1981年 | 233篇 |
| 1980年 | 165篇 |
| 1979年 | 98篇 |
| 1978年 | 121篇 |
| 1977年 | 101篇 |
| 1976年 | 72篇 |
| 1975年 | 61篇 |
排序方式： 共有10000条查询结果，搜索用时 15 毫秒
11.
Andrew J Lindford Heikki Mäkisalo Hannu Jalanko Jouni Lauronen Veli-Jukka Anttila Susanna Juteau Antti-Jussi Ämmälä Anna Eskola Samuli Saarni Helena Isoniemi Antti Mäkitie Patrik Lassus 《Journal of plastic, reconstructive & aesthetic surgery》2019,72(2):173-180
Aim
We herein describe the establishment of the Helsinki Vascularized Composite Allotransplantation (VCA) program and its execution in the first two face transplant cases.Methods & patients
The Helsinki VCA program initially required the fulfillment of legal, hospital, financial, and ethical requirements. Thereafter, the assembling of a multidisciplinary team commenced. A team of Plastic, maxillofacial and ENT surgeons comprise the facial VCA team. The protocol involves collaboration with the Solid Organ Transplant (SOT) team, transplant immunology, immunosuppression, microbiology, psychiatric evaluation, well-defined VCA indications and informed consent. Between 2011 and 2017 two patients were selected for transplantation. Both patients had a severe composite facial deformity involving the maxilla and mandible following earlier ballistic injury.Results
Patient 1 was a 35 year-old male who underwent successful near total face transplantation in February 2016 and at 30 months he has a good aesthetic outcome with symmetrical restoration of the central face and good sensory and symmetrical motor functional outcomes. Patient 2 was a 58 year-old male who underwent full face transplantation in March 2018 and at 5 months he has recovered without major problems.Conclusion
A successful facial VCA program requires a well-prepared research protocol, experts from multiple specialties and careful patient selection. The establishment of the Helsinki VCA program required long and thorough planning and resulted in the first two Nordic face transplantation cases. This protocol now forms the platform (as a proof of concept) for other types of vascularized composite allotransplantations. 相似文献12.
Satoru Kudose Dominick Santoriello Hanna Debiec Pietro A. Canetta Andrew S. Bomback M. Barry Stokes Ibrahim Batal Pierre Ronco Vivette D. D’Agati Glen S. Markowitz 《Kidney international》2021,99(1):247-255
- Download : Download high-res image (415KB)
- Download : Download full-size image
13.
14.
Aaron Yarlas Martha Bayliss Joseph C. Cappelleri Stephen Maher Andrew G. Bushmakin Lea Ann Chen Alireza Manuchehri Paul Healey 《Quality of life research》2018,27(2):273-290
Purpose
To conduct a systematic literature review of the reliability, construct validity, and responsiveness of the SF-36® Health Survey (SF-36) in patients with ulcerative colitis (UC).Methods
We performed a systematic search of electronic medical databases to identify published peer-reviewed studies which reported scores from the eight scales and/or two summary measures of the SF-36 collected from adult patients with UC. Study findings relevant to reliability, construct validity, and responsiveness were reviewed.Results
Data were extracted and summarized from 43 articles meeting inclusion criteria. Convergent validity was supported by findings that 83% (197/236) of correlations between SF-36 scales and measures of disease symptoms, disease activity, and functioning exceeded the prespecified threshold (r ≥ |0.40|). Known-groups validity was supported by findings of clinically meaningful differences in SF-36 scores between subgroups of patients when classified by disease activity (i.e., active versus inactive), symptom status, and comorbidity status. Responsiveness was supported by findings of clinically meaningful changes in SF-36 scores following treatment in non-comparative trials, and by meaningfully larger improvements in SF-36 scores in treatment arms relative to controls in randomized controlled trials. The sole study of SF-36 reliability found evidence supporting internal consistency (Cronbach’s α ≥ 0.70) for all SF-36 scales and test–retest reliability (intraclass correlation coefficient ≥0.70) for six of eight scales.Conclusions
Evidence from this systematic literature review indicates that the SF-36 is reliable, valid, and responsive when used with UC patients, supporting the inclusion of the SF-36 as an endpoint in clinical trials for this patient population.15.
16.
17.
18.
19.
20.