全文获取类型
收费全文 | 10104篇 |
免费 | 660篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 82篇 |
儿科学 | 175篇 |
妇产科学 | 116篇 |
基础医学 | 1306篇 |
口腔科学 | 576篇 |
临床医学 | 917篇 |
内科学 | 2217篇 |
皮肤病学 | 103篇 |
神经病学 | 1050篇 |
特种医学 | 289篇 |
外国民族医学 | 1篇 |
外科学 | 1958篇 |
综合类 | 40篇 |
一般理论 | 2篇 |
预防医学 | 578篇 |
眼科学 | 197篇 |
药学 | 662篇 |
中国医学 | 51篇 |
肿瘤学 | 494篇 |
出版年
2024年 | 12篇 |
2023年 | 118篇 |
2022年 | 237篇 |
2021年 | 414篇 |
2020年 | 228篇 |
2019年 | 349篇 |
2018年 | 437篇 |
2017年 | 282篇 |
2016年 | 296篇 |
2015年 | 362篇 |
2014年 | 496篇 |
2013年 | 592篇 |
2012年 | 903篇 |
2011年 | 887篇 |
2010年 | 490篇 |
2009年 | 451篇 |
2008年 | 652篇 |
2007年 | 670篇 |
2006年 | 578篇 |
2005年 | 543篇 |
2004年 | 430篇 |
2003年 | 356篇 |
2002年 | 299篇 |
2001年 | 67篇 |
2000年 | 44篇 |
1999年 | 60篇 |
1998年 | 47篇 |
1997年 | 37篇 |
1996年 | 32篇 |
1995年 | 13篇 |
1994年 | 15篇 |
1993年 | 11篇 |
1992年 | 27篇 |
1991年 | 35篇 |
1990年 | 27篇 |
1989年 | 21篇 |
1988年 | 43篇 |
1987年 | 24篇 |
1986年 | 32篇 |
1985年 | 13篇 |
1984年 | 14篇 |
1983年 | 12篇 |
1982年 | 13篇 |
1980年 | 7篇 |
1979年 | 16篇 |
1978年 | 8篇 |
1975年 | 10篇 |
1974年 | 18篇 |
1973年 | 13篇 |
1972年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Edgardo Pezzetta Alexandre Paroz Hans-Beat Ris Olivier Martinet 《European journal of cardio-thoracic surgery》2003,23(6):1062-1064
Spontaneous hemothorax is a rare and life threatening complication of neurofibromatosis. Two types of vascular involvement have been described: (a) stenotic or aneurysmal alterations in large vessels such as the aorta and its branches; and (b) dysplastic features in smaller vessels. Thoracotomy and surgical ligation of the bleeding vessels is primarily indicated in the presence of active bleeding with associated hemodynamic compromise. A more conservative approach with endovascular embolization or non-operative management have also been reported in case of hemodynamic stability. We present a rare case of spontaneous hemothorax treated conservatively in a patient with von Recklinghausen's disease. 相似文献
22.
23.
Clinical and molecular study of Corynebacterium diphtheriae systemic infections in France. Coryne Study Group.
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
O Patey F Bimet P Riegel B Halioua J P Emond E Estrangin S Dellion J M Alonso M Kiredjian A Dublanchet C Lafaix 《Journal of clinical microbiology》1997,35(2):441-445
Diphtheria is a disease with a long history that almost completely disappeared from developed countries. In addition, until 1987, systemic infections involving Corynebacterium diphtheriae were rare. However, in 1990, an epidemic occurred in Russia. These two circumstances have provided the stimulus to gain insight into the situation in France. In fact, between 1987 and 1993, a total of 59 C. diphtheriae strains were isolated. Epidemiological data were collected for patients from whom 40 strains were isolated from normally sterile sites, including 34 from blood cultures, and half of the bacteremic patients developed endocarditis. Osteoarticular involvement was noted in 11 of these 40 patients, including 5 bacteremic patients. The fatality rate following bacteremia was 36%, despite specific antibiotic treatment (beta-lactams and aminoglycosides). The mean age of the participants was 38 years, with half of the patients subsisting under low socioeconomic conditions and suffering from homelessness or alcoholism. Apparently, the skin turned out to be the major route of transmission in this reemerging disease. Eighty-eight percent of the isolates belonged to the C. diphtheriae biotype mitis. These were found predominantly in the Paris area, and most were of the same ribotype. Those isolates originating from the overseas territories (Guyana and New Caledonia) belonged to C. diphtheriae biotype gravis. No strains were positive for the tox gene by PCR. This study attests to the persistent circulation in France of C. diphtheriae in the form of systemic infections. The matter is especially significant since these strains are nontoxigenic and are of a unique ribotype. The strains are, however, sensitive to most antibiotics, although 20% are rifampin resistant. 相似文献
24.
Antoine Feydy MD PhD Alexandre Krainik MD Bernard Bussel MD Marc A. Maier PhD 《Journal of neuroimaging》2004,14(1):49-53
The authors report the case of a 33-year-old woman who exhibited, at the age of 17, a left-sided hemiplegia, which was followed by good motor recovery, though with a permanent deficit in fine finger movements. She had a widespread loss of neural tissue in the right hemisphere (crossed cerebrocerebellar atrophy), including (1) marked atrophy and thinning of the precentral and postcentral gyri; (2) widespread deep white matter destruction, including the corticospinal tract; and (3) crossed cerebellar atrophy. Except over the supplementary motor area (SMA), transcranial magnetic stimulation did not elicit motor evoked potentials in the affected hand. Nevertheless, during opening and closing of the affected hand, functional magnetic resonance imaging showed an activation of the lesioned primary sensorimotor cortex (SMC), as well as of the intact SMA and the parietal areas, but not of the ipsilateral motor areas. The authors speculate that recovery was achieved by a motor command generated in the SMC and the parietal cortex, passing through corticospinal axons originating in the SMA. 相似文献
25.
26.
Louis Boyer Jean M. Delorme Marc Alexandre Annie Boissier Pierre Gimbergues Gérard Glanddier J. Francois Viallet 《Cardiovascular and interventional radiology》1994,17(4):214-216
A 66-year-old man with atrial fibrillation was referred soon after developing left lower limb and abdominal pain with rectal bleeding. An immediate flush aortogram showed embolic occlusion of the left distal superficial femoral artery and superior mesenteric artery (SMA), 3 cm from its ostium. Recombinant tissue plasminogen activitor (rtPA) 40 mg was selectively in stilled in the SMA in two boluses. Abdominal symptoms resolved within 48 h, and complete recanalization of the SMA was shown on angiography. Exploratory laparotomy after 72 h showed a normal small bowel and right colon, and was completed by femoropopliteal embolectomy. Six months later, the patient remained asymptomatic. 相似文献
27.
P. Riegel F. I. S. Freitas G. Prévost C. Andronescu F. Bimet M. Kiredjian E. Estrangin J. P. Emond S. Dellion B. Halioua H. Monteil O. Patey 《European journal of clinical microbiology & infectious diseases》1997,16(8):610-614
Thirty-eight nontoxigenic strains ofCorynebacterium diphtheriae isolated between 1987 and 1992 from clinical specimens of French patients were typed by biotyping, antibiograms, bacteriophage
typing, ribotyping, and restriction analysis by pulsed-field gel electrophoresis (PFGE). Excellent correlation occurred between
the genotypes defined by PFGESfil profiles or by ribotypeBstEll profiles. Genotyping revealed seven genotype patterns among the 26 biotype mitis isolates, five among the nine biotype
gravis isolates, and three among the three biotype belfanti isolates. Phage typing was nonreactive for nine of the 38 isolates.
A combination of all the typing methods led to the identification of 19 different types ofCorynebacterium diphtheriae. 相似文献
28.
Liver transplantation, including the concept of reduced-size liver transplants in children. 总被引:4,自引:1,他引:3
下载免费PDF全文
![点击此处可从《Annals of surgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
C E Broelsch J C Emond J R Thistlethwaite P F Whitington A R Zucker A L Baker P F Aran D A Rouch J L Lichtor 《Annals of surgery》1988,208(4):410-420
Since the establishment of a clinical program in liver transplantation in 1984, 162 liver transplants have been performed in 131 patients (78 adults, 53 children). The patient mortality rate while waiting for a suitable organ has been 8% for adults and only 4% for children (25-46% reported in the literature). The low pediatric mortality is a result of the use of reduced-size liver transplants. A total of 14 procedures have been performed in recipients whose clinical condition was deteriorating and for whom no full-size graft could be located. Of 14 children, 13 were less than 3 years of age. Patient survival is 50%, comparable to survival of high-risk recipients of full-size livers. Using reduced-size liver grafting in a transplant program can lower mortality for children awaiting a transplant by overcoming size disparity. Reduced-size liver grafting will allow more effective use of donor resources and provide a potential avenue of research for organ splitting and living related donation. 相似文献
29.
30.
Ictal chronology and interictal spikes predict perfusion patterns in temporal lobe epilepsy: a multivariate study. 总被引:2,自引:0,他引:2
Lauro Wichert-Ana Tonicarlo Rodrigues Velasco Vera Cristina Terra-Bustamante Veriano Alexandre Ricardo Guarnieri Roger Walz Mery Kato Whemberton Martins Araújo Carlos Gilberto Carlotti David Araújo Antonio Carlos Dos Santos Américo Ceiki Sakamoto 《Seizure》2004,13(5):346-357
Typical (TPP) and atypical (APP) perfusion patterns (PP) may be seen in ictal SPECT of patients with temporal lobe epilepsy (TLE). APP may pose problem in the lateralization of the epileptogenic zone (EZ). We aimed to investigate predictive variables for the occurrence of TPP and APP. Fifty-one TLE patients were submitted to successful anterior-mesial temporal lobectomy. Univariate (UVA) and multivariate (MVA) analysis were performed upon clinical data, distribution of interictal spikes, and ictal chronology of seizures. From MVA, a final predictive model (FPM) was determined to better predict TPP and APP. Forty patients showed TPP (78.5%) and 11 patients APP (21.5%). Accuracy of ictal SPECT was higher in the unilateral (UIS) than in the bilateral (BIS) interictal spikes group (P = 0.05). FPM showed that patients exhibiting BIS, with shorter proportion of the electrographic seizure occurring after completion of tracer injection, and longer clinical than EEG seizure duration had more APP (P = 0.003). Generalized tonic-clonic seizures did not result in more APP. We concluded that analysis of ictal SPECT in TLE requires the knowledge of TPP and APP, the distribution of interictal spikes on temporal lobes and the ictal chronology of seizures. BIS showed that beyond a more complex epileptogenicity and seizure propagation, they may also lead to APP. 相似文献