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Ali Akbar Velayati Parissa Farnia Mohadese Mozafari Maryam Fatemeh Sheikholeslami Mona Afraei Karahrudi Payam Tabarsi Sven Hoffner 《The American journal of tropical medicine and hygiene》2014,90(1):99-105
We determined the prevalence of rifampin-monoresistant tuberculosis (RMR-TB) in Iran. Because development of RMR-TB is not common, we also identified the major risk factors associated with RMR-TB reported from different provinces of Iran. Data for 3,020 TB patients who remained or became smear positive after two, four, six, and nine months of standard first-line chemotherapy were retrospectively analyzed. Of 3,020 patients, 1,242 patients (41.1%) were culture and DNA positive for Mycobacterium tuberculosis. Of these patients, 73 (7.4%) patients had monoresistant isolates to rifampin, which was significantly higher than that for multidrug-resistant TB (5.8%). The average rate of RMR-TB in the studied population ranged from 5% to 10%. Classical investigation showed that 33.6% of patients had either a previous or family history of TB. Molecular epidemiology methods (i.e., spoligotyping and Mycobacterium intespersed repetitive unit–variable number tandem repeat), defined transmission link in three clusters (13%). These results outline the urgent need for a comprehensive plan for detection and treatment of RMR-TB cases. 相似文献
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Mehdi Nouraie Fatemeh Hosseinkhah Hassan Brim Behrouz Zamanifekri Duane T. Smoot Hassan Ashktorab 《Digestive diseases and sciences》2010,55(5):1442-1449
Background and Aims
Among the ethnic groups, the age-standardized incidence rate of colorectal cancer (CRC) is highest among African-Americans. The majority of CRC arise from preexisting adenoma. It is shown that 30% of the US adult population has adenomas. The potential risk of malignant transformation in adenomas differs by specific pathologic and clinical characteristics that we aimed to study in AAs. 相似文献35.
Jyoti Assudani M.B.B.S. Balwinder Singh M.B.B.S. Amena Samar M.B.B.S. Jasleen Pannu M.B.B.S. Amitoj Singh M.B.B.S. Fatemeh Nabavizadeh M.D. Preeti Singh M.D. Kiran K. Sunkavalli M.B.B.S. Navin C. Nanda M.D. 《Echocardiography (Mount Kisco, N.Y.)》2010,27(9):1147-1150
We describe a 77‐year‐old female with hypertrophic cardiomyopathy in whom live/real time three‐dimensional transesophageal echocardiography (3DTEE) provided incremental value over two‐dimensional transthoracic and transesophageal echocardiography (2DTTE, 2DTEE) and three‐dimensional transthoracic echocardiography (3DTTE) in making a more comprehensive assessment and a more confident diagnosis of caseous mitral annular calcification. 3DTEE revealed a portion of the mass to consist of small, multiple, highly echogenic discrete band‐like and punctate areas within a relatively much less echogenic stroma and surrounded by a well defined highly echogenic border. This appearance correlated with the pathological findings of calcific granules/strands located in a liquefied or semiliquefied interior providing a typical toothpaste like appearance. The highly echogenic outer border represented the residual outer portion or rim of the calcific mass which did not undergo liquefaction. These findings on 3DTEE which correlated with the toothpaste like appearance seen at surgery were not visualized on 2DTTE, 2DTEE, and 3DTTE. (Echocardiography 2010;27:1147‐1150) 相似文献
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The association between obesity and migraine in a population of Iranian adults: a case-control study
Ali Miri Morteza Nasiri Sahar Zonoori Fatemeh Yarahmad Arasb Dabbagh-Moghadam Gholamreza Askari Omid Sadeghi Masoumeh Asadi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(5):733-736
Aim
To assess the association between obesity and risk of migraine with aura and features of migraine attacks among a population of Iranian adults.Methods
In this case-control study, 102 confirmed cases of migraine with aura were matched based on age and gender with 102 healthy subjects. Data on demographic characteristics and anthropometric measurements were collected from all cases and controls by the same methods. Overweight and obesity were considered as body mass index ≥25–30?kg/m2 and?≥?30?kg/m2, respectively. Features of migraine attacks including frequency, duration and headache daily result were determined for patients based on international headache society criteria.Results
Mean age of subjects was 34.5?±?7.4 years and 77.9% of them were female. Compared with subjects with normal body mass index, those with obesity had greater odds for having migraine with aura (OR: 3.06, 95% CI: 1.11–8.43). Such finding was also seen even after adjusting for confounding variables; in a way that subjects with obesity were 2.92 times more likely for having migraine with aura compared with those with normal weight (OR: 2.92, 95% CI: 1.03-8.33). Among migraine with aura patients, we found that those with obesity had higher headache daily result compared with subjects with normal weight. However, obesity was not associated with frequency and duration of migraine attacks.Conclusions
We found that obesity was positively associated with risk of migraine with aura. In addition, subjects with obesity had higher headache daily result compared with those with normal weight. 相似文献38.
Fatemeh Beiraghdar Yunes Panahi Behzad Einollahi Eghlim Nemati Amirhossein Sahebkar Arash Hassanzadeh Hamid T. Khosroshahi Sima A. Azar Javid Safa Sadroddin R. Hashemi Jalal Etemadi Eisa T. Marzony Hamid Noshad 《Saudi Pharmaceutical Journal》2015,23(5):544-548
Background: The efficacy of human recombinant erythropoietins (rHuEPOs) in the treatment of anemia with different etiologies is proven. Development of biosimilar rHuEPO products with lower cost and wider availability is important for the care of anemic patients. Objective: The aim of the present study was to determine the bioequivalence and safety of a biosimilar rHuEPO (Pastopoitin®) and compare it with the innovator product Eprex®, as a standard rHuEPO. Methods: One hundred and seven anemic patients on stable hemodialysis were recruited to this randomized double-blind comparative trial and assigned to either subcutaneous Pastopoitin (n = 50) or Eprex (n = 57). Each study group received rHuEPO at a dose of 80–120 IU/kg/week in 2–3 divided doses for a period of 3 months. Hematologic parameters including Hemoglobin, hematocrit, RBC, EBC, platelet, MCV, MCH and MCHC were checked every 2 weeks. Blood iron, ferritin, TIBC, creatinine, BUN and electrolytes (Na, K, Ca and P) were evaluated monthly over the 3 months. Results: A significant increase in hemoglobin, hematocrit and RBC was observed by the end of study in both Pastopoitin and Eprex groups (p < 0.001). However, these factors were not significantly different between the groups, neither at baseline nor at the end of study (p > 0.05). Likewise, the groups were comparable regarding MCV, MCH, MCHC, iron, ferritin, TIBC, creatinine, BUN and electrolytes at baseline as well as at the end of trial. Adverse events were not serious and occurred with the same frequency in the study groups. Conclusion: Pastopoitin showed comparable efficacy and safety profile with Eprex in anemic patients on hemodialysis. Hence, Pastopoitin may be considered as a rHuEPO with a lower cost and wider availability compared with the innovator product Eprex. 相似文献
39.
Hassan Malekinejad Soheyl Varasteh Fatemeh Rahmani Hadi Cheraghi Arash Alizadeh Mehdi Behfar 《Toxin reviews》2015,34(2):101-108
This study was conducted to clarify the role of efflux transporter MRP2 in acetaminophen-induced hepatotoxicity in cats. Sixteen mixed bred male cats and four liver samples from mixed breed male dogs were used. The cats were assigned into four groups (n?=?4), received saline and 2, 10 and 50?mg/kg doses of acetaminophen orally for 14 days. Unlike the intact dogs, the MRP2 was not detectable in control cats. MRP2 at mRNA level was expressed in the liver of cats, which received the medium and high doses. Data suggest that the MRP2 expression may involve in the acetaminophen-induced hepatotoxicity in cats. 相似文献
40.
Fatemeh?Ramezani Mostafa?Habibi Hashem?Rafii-Tabar Massoud?AmanlouEmail author 《Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences》2015,23(1):9