全文获取类型
收费全文 | 1018篇 |
免费 | 60篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 19篇 |
妇产科学 | 18篇 |
基础医学 | 84篇 |
口腔科学 | 18篇 |
临床医学 | 87篇 |
内科学 | 153篇 |
皮肤病学 | 31篇 |
神经病学 | 94篇 |
特种医学 | 77篇 |
外科学 | 234篇 |
综合类 | 10篇 |
一般理论 | 1篇 |
预防医学 | 39篇 |
眼科学 | 10篇 |
药学 | 83篇 |
中国医学 | 2篇 |
肿瘤学 | 101篇 |
出版年
2023年 | 10篇 |
2022年 | 15篇 |
2021年 | 43篇 |
2020年 | 27篇 |
2019年 | 32篇 |
2018年 | 38篇 |
2017年 | 44篇 |
2016年 | 48篇 |
2015年 | 56篇 |
2014年 | 66篇 |
2013年 | 62篇 |
2012年 | 98篇 |
2011年 | 105篇 |
2010年 | 45篇 |
2009年 | 52篇 |
2008年 | 59篇 |
2007年 | 66篇 |
2006年 | 54篇 |
2005年 | 61篇 |
2004年 | 33篇 |
2003年 | 24篇 |
2002年 | 31篇 |
2001年 | 5篇 |
2000年 | 2篇 |
1999年 | 1篇 |
1998年 | 1篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1992年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有1086条查询结果,搜索用时 18 毫秒
91.
Moghimi Nasrin Davatchi Fereydoun Rahimi Ezat Saidi Afshin Rashadmanesh Naser Moghimi Solmaz Ghafori Hoshyar Zandi Peiman Ahmadi Negin Ghafori Hamed Moghimi Mohsen hajiheshmati Marjan 《Clinical rheumatology》2015,34(3):535-543
Clinical Rheumatology - This study aims to conduct an urban Community Oriented Program for Control Of Rheumatic Diseases (COPCORD) study in Sanandaj (Kurdistan, Iran). Sanandaj with a population of... 相似文献
92.
Adam N. Wallace Clifford G. Robinson Jeffrey Meyer Nam D. Tran Afshin Gangi Matthew R. Callstrom Samuel T. Chao Brian A. Van Tine Jonathan M. Morris Brian M. Bruel Jeremiah Long Robert D. Timmerman Jacob M. Buchowski Jack W. Jennings 《The oncologist》2015,20(10):1205-1215
The Metastatic Spine Disease Multidisciplinary Working Group consists of medical and radiation oncologists, surgeons, and interventional radiologists from multiple comprehensive cancer centers who have developed evidence- and expert opinion-based algorithms for managing metastatic spine disease. The purpose of these algorithms is to facilitate interdisciplinary referrals by providing physicians with straightforward recommendations regarding the use of available treatment options, including emerging modalities such as stereotactic body radiation therapy and percutaneous tumor ablation. This consensus document details the evidence supporting the Working Group algorithms and includes illustrative cases to demonstrate how the algorithms may be applied.
Implications for Practice:
The Metastatic Spine Disease Multidisciplinary Working Group algorithms can facilitate interdisciplinary referrals by providing physicians with straightforward recommendations regarding available treatment options, including emerging modalities such as stereotactic body radiation therapy and percutaneous tumor ablation. 相似文献93.
Blood pressure naturally rises with increasing age. The rate of change in blood pressure with age is regulated in part by genetic factors, but can also be altered through sustained dietary modification. Dietary approaches to modify blood pressure remain an important part of cardiovascular health promotion, which is especially important given the aging of the general population coupled with the increasing prevalence of obesity and metabolic disturbances. Specific modification of dietary components such as macronutrients and micronutrients could be helpful to lower blood pressure and alter the slope of blood pressure change whereas nutritional supplements are less likely to have a substantial beneficial effect. Population-wide generalizations regarding diet are impractical as individualized strategies are more likely to be successful in facilitating long-term benefits in improving blood-pressure control. Consequently, more effort needs to be focused on evaluating data from large-scale observational and interventional studies and interpreting their information in a clinically relevant manner, which is likely to be helpful for individual patients. Providing education on the relationship between diet and blood pressure from an early age is most likely to produce tangible benefits. 相似文献
94.
95.
Afshin Heidar Abady Richard Rosedale Tom J. Overend Bert M. Chesworth Michael A. Rotondi 《Journal of Manual and Manipulative Therapy》2014,22(4):199-205
Objective:
To investigate the inter-examiner reliability of Mechanical Diagnosis and Therapy (MDT)-trained diplomats in classifying patients with shoulder disorders. The MDT system has demonstrated acceptable reliability when used in patients with spinal disorders; however, little is known about its utility when used for appendicular conditions.Methods:
Fifty-four clinical scenarios were created by a group of 11 MDT diploma holders based on their clinical experience with patients with shoulder pain. The vignettes were made anonymous, and their clinical diagnoses sections were left blank. The vignettes were sent to a second group of six international McKenzie Institute diploma holders who were asked to classify each vignette according to the MDT categories for upper extremity. Inter-examiner agreement was evaluated with kappa statistics.Results:
There was ‘very good’ agreement among the six MDT diplomats for classifying the McKenzie syndromes in patients with shoulder pain (kappa = 0.90, SE = 0.018). The raw overall level of multi-rater agreement among the six clinicians in classifying the vignettes was 96%. After accounting for the actual MDT category for each vignette, kappa and the raw overall level of agreement decreased negligibly (0.89 and 95%, respectively).Discussion:
Using clinical vignettes, the McKenzie system of MDT has very good reliability in classifying patients with shoulder pain. As an alternative, future reliability studies could use real patients instead of written vignettes. 相似文献96.
Jonathan D. Kochav Jiwon Kim Robert Judd Han W. Kim Igor Klem John Heitner Dipan Shah Chetan Shenoy Afshin Farzaneh-Far Venkateshwar Polsani Ramsey Kalil Pablo Villar-Calle Lakshmi Nambiar Razia Sultana Michele Parker Preston Cargile Omar K. Khalique Martin B. Leon Jonathan W. Weinsaft 《JACC: Cardiovascular Imaging》2021,14(4):826-839
ObjectivesThe goal of this study was to test whether ischemia-mediated contractile dysfunction underlying the mitral valve affects functional mitral regurgitation (FMR) and the prognostic impact of FMR.BackgroundFMR results from left ventricular (LV) remodeling, which can stem from myocardial tissue alterations. Stress cardiac magnetic resonance can assess ischemia and infarction in the left ventricle and papillary muscles; relative impact on FMR is uncertain.MethodsVasodilator stress cardiac magnetic resonance was performed in patients with known or suspected coronary artery disease at 7 sites. Images were centrally analyzed for MR etiology/severity, mitral apparatus remodeling, and papillary ischemia.ResultsA total of 8,631 patients (mean age 60.0 ± 14.1 years; 55% male) were studied. FMR was present in 27%, among whom 16% (n = 372) had advanced (moderate or severe) FMR. Patients with ischemia localized to subpapillary regions were more likely to have advanced FMR (p = 0.003); those with ischemia localized to other areas were not (p = 0.17). Ischemic/dysfunctional subpapillary myocardium (odds ratio: 1.24/10% subpapillary myocardium; confidence interval: 1.17 to 1.31; p < 0.001) was associated with advanced FMR controlling for infarction. Among a subgroup with (n = 372) and without (n = 744) advanced FMR matched (1:2) on infarct size/distribution, patients with advanced FMR had increased adverse mitral apparatus remodeling, paralleled by greater ischemic/dysfunctional subpapillary myocardium (p < 0.001). Although posteromedial papillary ischemia was more common with advanced FMR (p = 0.006), subpapillary ischemia with dysfunction remained associated (p < 0.001), adjusting for posteromedial papillary ischemia (p = 0.074). During follow-up (median 5.1 years), 1,473 deaths occurred in the overall cohort; advanced FMR conferred increased mortality risk (hazard ratio: 1.52; 95% confidence interval: 1.25 to 1.86; p < 0.001) controlling for left ventricular ejection fraction, infarction, and ischemia.ConclusionsIschemic and dysfunctional subpapillary myocardium provides a substrate for FMR, which predicts mortality independent of key mechanistic substrates. 相似文献
97.
Hubbard MO Fu P Margevicius S Dowlati A Linden PA 《The Journal of thoracic and cardiovascular surgery》2012,143(6):1307-1313
98.
99.
100.
Rahmanian-Schwarz A Rothenberger J Amr A Jaminet P Schaller HE 《Annals of plastic surgery》2012,69(5):535-539