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991.
Background
Nurse turnover has a negative impact on the ability to meet patient needs and provide a high quality of care, which may create more stress on other staff due to increased workloads. This can lead to critical changes in the behavior of nurses towards their jobs resulting in low work satisfaction, low productivity, and leaving the organization. Thus, this study aimed to assess the quality of nursing work life (QNWL), to explore the nurses’ turnover intention and to examine the correlation between QNWL and nurses’ turnover intention.Methods
A cross-sectional survey was conducted on nurses with at least 1 year of nursing experience at two hospitals selected randomly from Riyadh, Saudi Arabia: King Fahad Medical City and King Faisal Specialized Hospitals. Data were collected using a self-administered questionnaire comprising four sections (Brooks’ survey of QNWL, Anticipated Turnover Scale (ATS), open-ended questions and demographic characteristics).Results
A sample of 364 nurses was recruited. Results proposed that the participants were dissatisfied with their work life (54.7%), with almost 94% indicating a turnover intention from their current hospital. Moreover, 154 (93.3%) out of 165 nurses who reported satisfaction with QNWL indicated the intention to turnover. The correlation between QNWL and ATS for binary variables was too week (r?=???0.024) and statistically not significant (p?=?0.206).Conclusion
The QNWL and nurse turnover are challenging issues for healthcare organizations because of its consequences and impact on patient care. Our study provided critical findings low indication satisfaction of nurses with their QNWL and a high turnover intention. The results of this study could be used as a nexus for the development of regulations and practical strategies to enhance QNWL and to decrease the turnover.992.
993.
Marina A Njelekela Alfa Muhihi Rose N. M. Mpembeni Amani Anaeli Omary Chillo Sulende Kubhoja Benjamin Lujani Davis Ngarashi Mwanamkuu Maghembe 《Nigerian medical journal》2015,56(2):103-108
Background:
Childhood obesity has increased over the past two decades. Child obesity is likely to persist through adulthood and increases the risk of non-communicable diseases (NCDs) later in life. This study assessed knowledge and attitudes towards obesity among primary school children in Dar es Salaam, Tanzania.Materials and Methods:
A cross-sectional study was conducted in randomly selected primary schools in Dar es Salaam. A structured questionnaire was used to assess the knowledge and attitudes. Anthropometric and blood pressure measurements were taken using standard procedures.Results:
A total of 446 children were included in the analysis. The mean age of the participants was 11.1 ± 2.0 years. The mean body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 16.6 ± 4.0 kg/m2, 103.9 ± 10.3 mmHg and 65.6 ± 8.2 mmHg, respectively. Prevalence of obesity (defined as BMI >95th percentile for age and sex) was 5.2%. Half of the children (51.1%) had heard about obesity from teachers at school (20%), radio (19.4%) and books/newspaper (17.3%). Less than half (45.4%) had knowledge about the risk factors for childhood obesity and correctly defined obesity (44.6%). However, a good number of the children (72.1%) were aware that they can be affected by obesity. Majority of them had negative attitude towards obesity and various factors leading to or resulting from childhood obesity.Conclusions:
Knowledge about childhood obesity among primary school children is moderate and have negative attitude towards obesity. Integrating educational programs early in primary schools may be an effective strategy to impact knowledge about obesity and other non-communicable diseases early in childhood. 相似文献994.
Robert M. Rifkin Sundar Jagannath Brian G.M. Durie Mohit Narang Howard R. Terebelo Cristina J. Gasparetto Kathleen Toomey James W. Hardin Lynne Wagner Kejal Parikh Safiya Abouzaid Shankar Srinivasan Amani Kitali Faiza Zafar Rafat Abonour 《Clinical therapeutics》2018,40(7):1193-1202.e1
Purpose
Maintenance therapy after autologous stem cell transplantation (ASCT) improves clinical outcomes in multiple myeloma (MM), but the effect of continued treatment with lenalidomide-only maintenance, or any maintenance, on health care resource utilization (HCRU) is largely unknown.Methods
Here we present an analysis of HCRU and clinical outcomes in a cohort of patients from the Connect MM registry, the largest, ongoing, observational, prospective US registry of patients with symptomatic newly diagnosed MM. In this study, patients with newly diagnosed MM who completed induction and single ASCT without subsequent consolidation received lenalidomide-only maintenance (n?=?180), any maintenance (n?=?256), or no maintenance (n?=?165). HCRU (hospitalization, surgery/procedures, and concurrent medications [growth factors, bisphosphonates, or neuropathic pain medication]) was assessed starting from 100 days post-ASCT for up to 2 years.Findings
Although the rates of hospitalization per 100 person-years were similar across groups at the end of years 1 and 2, the median duration of hospitalization was numerically longer with no maintenance. The rates of use of growth factors, bisphosphonates, and neuropathic pain medication were generally similar in all 3 groups. The receipt of any maintenance was associated with significantly reduced use of neuropathic pain medications during year 1. Of note, lenalidomide-only maintenance was associated with significantly longer progression-free survival (54.5 vs 30.4 months; hazard ratio [HR]?=?0.58; 95% CI, 0.43–0.79; P?=?0.0005) and overall survival (OS) (median OS not reached in either group; HR?=?0.45; 95% CI, 0.28–0.73; P?=?0.001) compared with no maintenance. Likewise, the group treated with any maintenance had significantly longer median progression-free survival (44.7 vs 30.4 months; HR?=?0.62; 95% CI, 0.47–0.82; P?=?0.0008) and OS (median OS not reached in either group; HR?=?0.50; 95% CI, 0.33–0.76; P?=?0.001) than did the group that did not receive maintenance.Implications
These findings suggest that in this largely community-based study population, post-ASCT maintenance therapy, including lenalidomide-only maintenance, improves clinical outcomes without negatively affecting HCRU. ClinicalTrials.gov identifier: NCT01081028. 相似文献995.
996.
Soma Sengupta Shyamal Dilhan Weeraratne Hongyu Sun Jillian Phallen Sundari K. Rallapalli Natalia Teider Bela Kosaras Vladimir Amani Jessica Pierre-Francois Yujie Tang Brian Nguyen Furong Yu Simone Schubert Brianna Balansay Dimitris Mathios Mirna Lechpammer Tenley C. Archer Phuoc Tran Richard J. Reimer James M. Cook Michael Lim Frances E. Jensen Scott L. Pomeroy Yoon-Jae Cho 《Acta neuropathologica》2014,127(4):593-603
997.
998.
Manal M. Alkhulaifi Amani S. Awaad Hind A. AL-Mudhayyif Monerah R. Alothman Saleh I. Alqasoumi Sarah M. Zain 《Saudi Pharmaceutical Journal》2019,27(3):401-405
Seven fungal species were isolated from soil samples collected from the University of Sultan Qaboos, Muscat, Sultanate of Oman. The fungal isolates were identified as Aspergillus athecius, A. terreus var. africans, A. flavus, A. terreus, A. foetidus, Fusarium chlamydosporum and F. nygamai. Phytochemical and chromatographic investigation showed variety of secondary metabolites in all of the fugal extracts (extra and intra cellular). The antimicrobial activity of internal and external extracts of the isolated fungal species were screened against Candida albicans, C. glabrata, C. parapsilosis, C. tropicalis, Pseudomonas aeruginosa, Lactobacillus acidophilus, Streptococcus gordonii, S. mutans. The antimicrobial activity of external secondary metabolites was generally better than the internal metabolites. The highest antimicrobial activity (32?mm, 30?mm and 29?mm) was obtained from external secondary metabolites of Aspergillus flavus against Candida tropicals, Candida parapsilosis and Candida albicans, respectively. 相似文献
999.
1000.
Shayan Abbasi Ali Afrasiabi Ali Akbar Karimi Zarchi Mohammad Ali Faramarzi Gholamreza Tavoosidana Amir Amani 《Journal of pharmaceutical innovation》2014,9(2):115-120