以积极优质服务提高育龄群众生殖健康水平

计划生育优质服务代表最广大人民群众的根本利益,是江泽民总书记“三个代表”重要思想的具体体现。开展优质服务必须以人的全面发展为中心,以服务和管理相结合为依托,实现工作思想和工作方法构转变;要以技术服务为重点,围绕生育、节育、不育开展生殖保健服务,积极推进避孕方法和知情选择,努力提高出生人口素质,并开展妇女病的普查和防治。     

髋关节结核的DR平片与MRI分析

目的：分析髋关节结核的DR平片及MRI表现。方法收集我院近年来经手术病理证实或经临床治疗观察确诊的15例髋关节结核患者,均行DR平片检查,其中6例行M RI检查。回顾性分析髋关节结核的平片及M RI表现。结果骨性髋关节结核2例,滑膜型髋关节结核3例,全髋关节结核10例。结论 D R平片是筛选病变最简单、最经济的主要手段;MRI能够发现早期微小病变的显示,特别是对关节滑膜、软骨、软骨下骨及关节囊的显示较DR平片及CT 更清晰,对病变的早期诊断及术前病灶部位和范围的显示具有重要的价值。     

支气管动脉灌注化疗及栓塞术在肺癌综合治疗中的作用

目的探讨支气管动脉灌注化疗及栓塞术在肺癌综合治疗中的作用。 方法对78例病理确诊为肺癌的患者,行经支气管动脉灌注化疗及栓塞术,术后根据具体情况再选择手术、化学消融及射频消融、放疗等综合治疗。 结果78例患者中,支气管动脉灌注化疗及栓塞术后,有9例进行了手术切除,9例进行了射频消融,36例进行了放疗;放疗后复发再次行支气管动脉灌注化疗及栓塞术15例,单纯灌注化疗栓塞9例。 结论肺癌的治疗应采取综合治疗手段,需要综合分析,确立个体化的治疗方案,以最有利于患者为出发点,支气管动脉灌注化疗及栓塞术在肺癌综合治疗中起到很重要的作用,为手术切除、放疗、化学消融及射频消融等治疗手段提供了机会和可能。     

孟鲁司特钠对AECOPD患者血清IL-13、TNF-α水平及肺功能的影响

目的探讨孟鲁司特钠对慢性阻塞性肺疾病急性加重期(AECOPD)患者血清白细胞介素-13(IL-13)、肿瘤坏死因子-α(TNF-α)水平及肺功能的影响。方法将100例AECOPD患者按入院的先后顺序分为研究组和对照组,每组50例。2组均采用常规治疗。在此基础上,研究组加用孟鲁司特钠片治疗。分别检测2组治疗前、治疗14d后血清IL-13、TNF-α水平及肺功能指标[肺活量(FVC)、最大呼气峰流速(PEF)、第1秒用力呼气容积(FEV1)和第1秒用力呼气容积占用力肺活量之比(FEV1/FVC)比值]的变化。结果与对照组比较,研究组治疗14d后血清IL-13、TNF-α水平均明显降低,FVC、PEF、FEV1及FEV1/FVC比值则均明显升高(均P<0.05)。结论孟鲁司特钠治疗AECOPD能够明显改善患者的肺功能,降低患者的体内炎症因子水平。 更多还原     

雾化吸入灭活草分枝杆菌治疗中度支气管哮喘的临床研究

Objective To introduce inhaled inactivated-mycobacterium phlei on prevention and treatment of moderate bronchial asthma to observe the clinical effect. Method This study was a prospective and controlled study. The patients diagnosed with asthma in our out-patient from March 2009 to December 2010 were collected, who met the following conditions were included in the study: age≥ 14 years; met the criteria of moderate chronic persistent bronchial asthma in Global Initiative for Asthma (GINA) in 2008; suspended receiving systemic corticosteroids, Montelukast, ketotifen and other anti-inflammatory and anti-allergic drugs in one month; no significant respiratory tract infections; and other serious illnesses or abnormalities known.A total of 100 patients with asthma were selected, including 37 males and 63 females, age (32.11 ± 12.95 )years. The patients were randomly(random number) divided into two groups: A group(treatment group; 16males and 34 females, age 33.56 ± 14.23 years) and B group (control group; 21 males and 29 females,age 30.66 ± 11.50 years); 50 in each group. No significant difference was noted between the two groups on age and gender composition. The patients in A group were treated with inhaled inactivated-mycobacterium phlei F. U. 36 Injection 1.72 μg/mL × 2 that adding 3 mL normal saline, once a day for 5 days. The patients in B group were treated with salmeterol xinafoate and fluticasone propionate powder for inhalation (50/100 μg), twice daily for sustainable use. The patients in the two groups were observed for one month. During this course, the patients in the two groups could inhale the salbutamol sulphate aerosol as need to relieve symptoms. And the number of using was recorded. Pulmonary function test and asthma provocative test were carried out on the Day O, 6 and 31. ACT scores were measured before and after the treatment. Results On Day 6 and 31 after treatment, the negative conversion rates of asthma provocative test of the patients in A group were 82% and 78% respectively, B group were 84% and 90% respectively. Provocative test of the patients in the two groups were negative conversion significantly before and after treatment. There was no significant difference between the two groups by chi-square test (P ＞ 0. 05 ). Completely random designed data was analyzed by analysis of variance. The analysis showed that the accumulated doses of methacholine of the patients in the two group increased significantly ( P ＜ 0. 05 ), but no difference between the two groups.There was a improvement trend on forced expiratory volume in one second( FEV1 )of the patients in A group after treatment, but no difference. FEV1 of the patients in B group increased significantly higher ( P ＜0.05), which was significantly higher than A group on the 31th day (P ＜0. 05); Peak expiratory flow (PEF) of the patients in the two group increased significantly on Day 6 and 31 after treatment (P ＜0.05 ).On Day 31, B group was significantly higher than A group ( P ＜ 0. 05 ); Scores of asthma control test (ACT)of the patients in the two group were significantly increased, and the number of using of salbutamol sulfate aerosol was significantly reduced (P ＜0.01 ). B group was obvious than group A (P ＜0.05 ). During treatment, there were only two adverse reaction cases of transient low fever; most obvious was on the third day.Conclusions Inhaled inactivated-mycobacterium phlei would inhibit the airway hyperresponsiveness of the patients with moderate bronchial asthma in short time, improve the symptoms, reduce the acute exacerbation, and reduce the use of rescue medication, which has the roles of prevention and treatment of moderate asthma in a certain period of time.     

改良下斜肌切断术治疗伴下斜肌功能亢进的V型斜视

目的：探讨改良下斜肌切断术治疗伴下斜肌功能亢进的 V 型斜视的疗效。方法对68例（106眼）伴下斜肌功能亢进的 V 型斜视行改良下斜肌切除联合水平直肌后退及（或）缩短术,术后观察评价下斜肌功能、眼位及双眼单视功能。结果术后100眼（94.3%）下斜肌功能亢进消失、6眼（5.6%）下斜肌亢进、无下斜肌功能不足者。术前水平斜视角平均64.5△,术后9.2△,术前垂直斜视角平均15.8△,术后随访为2.2△,平均降低13.6△。术前7例（12.5%）有双眼单视功能,术后47例（73.5%）有不同程度的双眼单视功能。结论改良下斜肌切断术是伴下斜肌功能亢进的 V 型斜视的有效术式。     

雷公藤多甙对类风湿关节炎患者血浆TNFα水平影响的研究

为探讨雷公藤多甙（TⅡ）对类风湿关节炎（RA）患者血浆肿瘤坏死因子α（TNFα）水平的影响,用放射免疫分析（RIA）法研究了30例RA患者TⅡ(20mg每天3次）治疗前后血浆TNFα水平的变化。结果显示TⅡ治疗12周后血浆TNFα水平明显降低（P＜0．01）,与对照组比较差异明显（P＜0．01）,临床指标的改善也优于对照组（P＜0．01）。表明TⅡ能有效地降低RA患者TNFα水平,并使病情改善。     

女性乳腺癌危险因素BRCA1基因突变的观察

目的检测有危险因素者BRCA1第11外显子的突变率。方法38例有危险因素者,年龄29-71岁,有乳腺癌及卵巢癌家族史18例,其中3例本人患乳腺癌;有其他恶性肿瘤家族史者17例;有良性病变者8例,其中1例本人患宫颈癌。25例无危险因素者为对照组。受检者抽取外周血进行DNA提取,经PCR扩增后测序,与NCBI基因库比对。结果1例乳腺良性病变伴宫颈癌者检出4个碱基的缺失突变。危险因素组与对照组另检出6个相同位点的突变,其中5个位点在危险因素组和对照组突变率分别为65.8%和36.0%,两组间存在显著差异（P〈0.05）。结论发生于性器官的恶性肿瘤可能有共同的突变位点,危险因素组突变率显著高于对照组,提示家族性乳腺癌可能与更常见的、低外显率基因变异的综合作用有关。     

肺癌与哮喘、肺结核关系探讨（附4176例分析）

目的：探讨原发性支气管肺癌（肺癌）与支气管哮喘（哮喘）、肺结核之间的关系。方法：对4176例住院肺癌病例的一般情况、诊断情况进行统计,并比较其中肺结核、哮喘的并发情况。结果：出院诊断“肺癌”的患者有4176例,其中同时诊断结核或曾有结核病史的有460例,占11．02％,同时诊断哮喘或曾有哮喘病史的有32例,占0．77％,两者比较差异有统计学意义（P〈0.001）。以确诊（有病理或细胞学依据）的2868例住院肺癌患者作为研究对象,其同时诊断结核或曾有结核病史的有200例,占6．97％;同时诊断哮喘或曾有哮喘病史的有20例,占0．70％,两者比较差异有统计学意义（P〈0.001）。结论：肺癌人群并发哮喘的机会与普通人群相仿,甚至更低,而肺癌与肺结核关系密切,肺癌人群并发肺结核的概率明显高于普通人群。     

不同品种菊花茶中重金属含量检测及溶出率分析

正饮茶已经成为全球范围内居民的生活行为和健康习惯,而花茶集茶味与特殊花香于一体,具有独特的保健功效成为老少皆宜的保健饮品。菊花是常见的花茶之一,有散风清热、平肝明目和解毒消炎等作用,为人体健康保驾护航[1-5]。菊花在种植和加工过程中均有可能引入重金属。在享受花茶的保健养生功效的同时,也要对菊花质量品质进行监控,特别是对菊花中重金属含量的监测以及对饮用菊花茶汤时所存在的健康风险进行评估[6-8]。菊花茶作为一种