腹背部热敷加按摩法治疗小儿消化系统疾病52例

目的 :观察腹背部热敷加按摩法治疗小儿消化系统疾病的疗效 ;方法 :予食盐 15 0 g炒热至 60℃左右 ,用纱布包裹 ,分别在腹部及背部反复按摩 ,每次 10～ 15分钟 ,每天 3～ 5次 ,同时配合少量口服药物以对症治疗 ;结果 :除急性阑尾炎所致腹痛效果较差 (总有效率为 5 0 % )和便秘稍差 (总有效率为 86.7% )外 ,其他情况所致消化不良、腹痛、腹泻等症 ,总有效率为 10 0 % ;结论 :用腹背部热敷加按摩法治疗小儿消化系统疾病具有效果好、使用简便、无副作用的优点 ,易于患儿及家长接受 ,克服了喂药难的弊端 ,值得推广使用     

Relationship between Carbachol Hyperstimulation-induced Pancreatic Intracelluar Trypsinogen and NF-κB Activation in Rats in vitro

The relationship between intracelluar trypsinogen activation and NF-κB activation in rat pancreatic acinar cells induced by M3 cholinergic receptor agonist （carbachol） hyperstimulation was studied. Rat pancreatic acinar cells were isolated, cultured and treated with carbachol, the active protease inhibitor （pefabloc） and NF-κB inhibitor （PDTC） in vitro. Intracelluar trypsin activity was measured by using a fluorogenic substrate. The activity of NF-κB was monitored by using electrophoretic mobility shift assay. The results showed that after pretreatment with 2 mmol/L pefabloc, the activities of trypsin and NF-κB in pancreatic acinar cells treated with high concertrations of carbachol （10^-3 mol/L） in vitro was significantly decreased as compared with control group （P〈0.01 ）. The addition of 10^-2 mol/L PDTC resulted in a significant decrease of NF-κB activities in pancreatic acinar cells after treated with high concertrations of carbachol （10^-3 mol/L） in vitro, but the intracelluar trypsinogen activity was not obviously inhibited （P〉0.05）. It was concluded that intracelluar trypsinogen activation is likely involved in the regulation of high concertrations of carbachol-induced NF-κB activation in pancreatic acinar cells in vitro. NF-κB activation is likely not necessary for high concertrations of carbachol-induced trypsinogen activation in pancreatic acinar cells in vitro.     

损伤控制手术在严重多发伤合并胰十二指肠损伤中的应用

目的探讨损伤控制手术在严重多发伤合并胰十二指肠损伤中的应用。方法回顾近5年来我院收治的4例严重多发伤合并胰十二指肠损伤的病例资料,总结在4例严重多发伤合并胰十二指肠损伤患者中主动采用损伤控制手术的具体应用方法及效果。结果4例多发伤情较重且合并胰十二指肠损伤的损伤严重度(ISS)评分均>16,并处于生理极限状态,应用损伤控制手术首先进行止血和制止肠内容物的外溢、行消化道未重建的胰十二指肠切除术、胰管及胆管外引流、临时关腹等简化手术,随后送到外科ICU待血液动力学稳定,在监护48h后再次行彻底性手术,均痊愈。结论运用损伤控制手术并分阶段重建消化道,对严重多发伤合并胰十二指肠损伤并处于生命极限的患者是有益的,并可显著地降低胰十二指肠损伤患者的死亡率。     

无机元素在裸叶紫珠不同器官中的分布

目的 探讨无机元素在裸花紫珠的叶、花和果实中分布情况.方法 采用电感耦合等离子体原子发射光谱法(ICP-OES)测定裸花紫珠的叶、花和果实中的Ca、Mg等20种无机元素含量,对无机元素在裸花紫珠中的分布进行分析.结果 大多数无机元素在裸花紫珠中不同器官的分布存在明显差异,Co和Ni两种元素在果实中的含量高于叶和花.Al、Ca、Mg和Pb在叶的含量高于其他两个器官.花中B、Ba、Cu、Fe、Mn、Sr和Zn的含量高于叶和果实;Cu在叶和花中的含量超过了国家标准规定的限量.结论 裸花紫珠的无机元素分布特征能为其品系鉴别、栽培及应用提供一定的依据.