备孕妇女补充复合营养素安全性分析

目的调查备孕妇女通过饮食摄取的各种营养素的情况,分析补充复合营养素在优生优育中的安全性。方法使用饮食营养调查的半定量食物频率调查法分析了扬州市区2014年7月至2016年5月共259例备孕妇女的饮食营养状况。结果通过调查备孕妇女的进食情况,发现摄取的营养素存在以下问题:低于推荐量的人数达50%以上的,仅碘、叶酸、钙三种,其余营养素低于推荐量的人数均不多。结论对备孕妇女进行膳食营养状况评价、指导,有针对性的补充复合营养素,减少营养素之间的相互影响,更能达到预防出生缺陷,提高人口素质的目的。     

对山西医科大学生诚信意识现状的调查与分析

[目的]了解目前大学生诚信意识的现状，为提高大学生思想素质提供参考。[方法]对山西医科大学841名在校大学生进行问卷调查，将有效问卷输入计算机建立数据库，用统计软件进行统计分析。[结果]分别有94．17％、2．73％、3．09％的大学生对“诚信是一个人最重要的品质”的说法表示同意、不同意和难以判断；有94．17％的大学生赞成并努力践行“以诚实守信为荣，见利忘义为耻”的荣辱观；有4.7％的大学生赞戍但做不到，有1．07％的大学生持无所谓态度；在谈到考试作弊的问题时，有54．34％的大学生表示反感，19．98％的大学生表示可以理解，18．55％的大学生认为作弊好过补考，7．13％的大学生坦白自己也曾作过弊；大学生对自身诚信意识进行评价，认为诚信意识一般的占50．89％，认为强和弱的分别占36．15％和12．96％。[结论]绝大多数学生具有较明确的诚信观念，对诚信的意义和作用有较充分的认识，但是大学生自身对当代大学生诚信意识的评价较低。     

抗突变型瓜氨酸波形蛋白抗体在类风湿关节炎中的诊断价值

Objective To assess the diagnostic value of anti-mutated citrullinated vimentin antibodies (anti-MCV) for rheumatoid arthritis (RA), and compare it with anti-cyclic citrullinated peptide antibodies (anti-CCP), rheumatoid factors (RF). Methods Commercially available enzyme-linked immunosorbent assay (ELISA) kit was used to detect anti-MCV antibodies in a group of 177 RA patients, 46 patients with other rheumatic diseases, and 48 healthy blood donors. At the same time, anti-CCP, RF were detected. T test and χ2 test were selected. Results The average concentration of anti-MCV was (523±376) U/ml in RA, (96± 55) U/ml in patients with other rheumatic diseases, (34±18) U/ml in healthy controls. Different threshold levels (20, 40, 60, 80, 100, 120, 140 U/ml) for positive results were calculated bythe areas under the ROC curve (the areas were 0.521, 0.706, 0.769, 0.791, 0.816, 0.826, 0.822), then the best diagnosis efficacy for RA was determined as more than 120 U/ml. At this level, the sensitivity and the specificity for anti-MCV were 80.1% and 80.9% for RA diagnosis. The positive and negative predictive value were 92% and 67.8%. Comparing with anti-CCP, anti-MCV showed comparable specificity but higher sensitivity. And it's also better than RF apparently. If all 3 antibodies were detected at the same time, or anti-MCV combine with one of them, the sensitivity would increase to 95.7%. In addition, Anti-MCV showed positive in 32 of 67(55.2%) patients with RA whose anti-CCP was negative, meanwhile 31 of 59 (52.5%) patients with RA whose RF was negative. Conclusion RF and anti-CCP are complementary in diagnosing RA. The combination detection of RF and anti-CCP could significantly improve the specificity for the diagnosis of RA.     

继发于真性红细胞增多症急性痛风一例报告

痛风（gout）是嘌呤代谢障碍引起的一组异质性慢性代谢性疾病,其临床特点为高尿酸血症、反复发作的急性关节炎、间质性肾炎和痛风石形成。严重者可出现关节畸形及功能障碍,常伴有酸性尿路结石,且常伴发肥胖、高脂血症、高血压、糖尿病和心脑血管病[1]。     

抗突变型瓜氨酸波形蛋白抗体在类风湿关节炎中的诊断价值

Objective To assess the diagnostic value of anti-mutated citrullinated vimentin antibodies (anti-MCV) for rheumatoid arthritis (RA), and compare it with anti-cyclic citrullinated peptide antibodies (anti-CCP), rheumatoid factors (RF). Methods Commercially available enzyme-linked immunosorbent assay (ELISA) kit was used to detect anti-MCV antibodies in a group of 177 RA patients, 46 patients with other rheumatic diseases, and 48 healthy blood donors. At the same time, anti-CCP, RF were detected. T test and χ2 test were selected. Results The average concentration of anti-MCV was (523±376) U/ml in RA, (96± 55) U/ml in patients with other rheumatic diseases, (34±18) U/ml in healthy controls. Different threshold levels (20, 40, 60, 80, 100, 120, 140 U/ml) for positive results were calculated bythe areas under the ROC curve (the areas were 0.521, 0.706, 0.769, 0.791, 0.816, 0.826, 0.822), then the best diagnosis efficacy for RA was determined as more than 120 U/ml. At this level, the sensitivity and the specificity for anti-MCV were 80.1% and 80.9% for RA diagnosis. The positive and negative predictive value were 92% and 67.8%. Comparing with anti-CCP, anti-MCV showed comparable specificity but higher sensitivity. And it's also better than RF apparently. If all 3 antibodies were detected at the same time, or anti-MCV combine with one of them, the sensitivity would increase to 95.7%. In addition, Anti-MCV showed positive in 32 of 67(55.2%) patients with RA whose anti-CCP was negative, meanwhile 31 of 59 (52.5%) patients with RA whose RF was negative. Conclusion RF and anti-CCP are complementary in diagnosing RA. The combination detection of RF and anti-CCP could significantly improve the specificity for the diagnosis of RA.     

癌生长的分形模型

对迄今文献上可发表的癌生长的分形模型进行了简短详述,指出这些模型的优缺点。建立了癌生长的DLA型改良分形模型,并由此法求出了分维。     

骨桥蛋白在类风湿关节炎患者血清中的表达及意义

<正>近年来对骨桥蛋白[1]的研究除了在肿瘤方面以外,还发现其在炎症反应和自身免疫性疾病发病过程中起着重要作用[2,3]。本研究通过检测骨桥蛋白在RA患者外周血中     

宫颈环扎术治疗宫颈功能不全28例临床分析

目的了解宫颈功能不全的病因,探讨宫颈环扎术治疗宫颈功能不全的手术时机和疗效。方法对2007年3月—2008年9月我院收住的28例病例进行回顾性分析。结果宫颈环扎术能延长孕龄,28例患者中有21例获得足月妊娠。结论宫颈环扎术对预防宫颈功能不全所致晚期习惯性流产效果良好,值得推广。     

系统性红斑狼疮合并二次弥漫性肺泡出血一例并文献复习

<正>系统性红斑狼疮(SLE)合并弥漫性肺泡出血(DAH)临床少见,病情凶险,病死率高,并且因其临床表现不特异,常易被漏诊或误诊,而短时间内连续发生两次DAH临床更是罕见。我们收治了1例SLE患者住院期间连续发生2次DAH,并获得成功救治。本文通过分析其临床特点及诊治经过,并复习相关文献,以期提高对此类危重病例的诊治水平。