经阴道彩色多普勒超声检测子宫动脉血流参数与受孕的相关性研究

目的采用经阴道彩色多普勒超声检测子宫动脉与子宫螺旋动脉的血流动力学参数与子宫内膜厚度、子宫内膜容度及它们之间的相关性,观察其结果对育龄妇女受孕情况的影响。方法选取就诊的育龄妇女67例,分成观察组(原发性不孕)31例,对照组(正常受孕并分娩后)36例,经阴道彩色多普勒超声检查两组子宫内膜厚度、子宫内膜容度、子宫动脉及子宫螺旋动脉搏动指数(PI)、阻力指数(RI)、收缩期峰值流速与舒张期峰值流速之比(S/D),观察两组以上检测结果的差异,以及不孕组子宫内膜厚度、子宫内膜容度与子宫动脉及子宫螺旋动脉PI、RI、S/D之间的相关性。结果两组子宫内膜厚度与子宫内膜容度差异显著(P<0.01)。两组子宫动脉、子宫螺旋动脉PI、RI、S/D检测值均有显著差异(P<0.05)。对照组子宫内膜厚度、子宫内膜容度与子宫动脉及子宫螺旋动脉PI、RI、S/D呈显著相关性(P<0.05)。结论育龄期妇女子宫动脉与子宫螺旋动脉血流动力学对子宫内膜厚度、子宫内膜容度影响比较大,采用经阴道彩色多普勒超声检测子宫动脉与子宫螺旋动脉的血流动力学参数与子宫内膜厚度、子宫内膜容度及它们之间的相关性对预测妇女受孕情况有一定的临床参考价值。     

冠修复与Cortisomol糊剂根管充填同步治疗隐裂性牙髓病近期疼痛与远期疗效观察

目的研究冠修复与Cortisomol糊剂根管充填同步治疗隐裂性牙髓病近期疼痛与远期疗效。方法将隐裂性牙髓病患者纳入研究,随机分为给予纤维桩冠修复联合Cortisomol糊剂根管充填治疗的观察组以及给予金属桩联合Cortisomol糊剂根管充填治疗的对照组,观察术后疼痛情况、牙齿相关指标及生活质量。结果观察组患者的NRS评分以及牙龈指数(0.36±0.06)、出血指数(0.43±0.06)、松动度(0.54±0.08)均低于对照组;咀嚼效率(0.89±0.11)、咬合力(135.4±21.4)lbs以及生活质量评分明显高于对照组。结论纤维桩冠修复联合Cortisomol糊剂根管充填治疗有助于缓解患者术后疼痛、改善牙齿功能、提高生活质量,具有积极的临床价值。     

The clinical application of identification of Aspergillus spp.using ITS and β-tubulin gene sequences

Objective To study the clinical application of the ITS and β-tubulin gene regions in identification of Aspergillus spp. Methods One hundred and twenty-four Aspergillus strains that isolated from fungal rhino-sinusitis specimens were collected in Beijing Tongren Hospital, Capital Medical University from July 2007 to January 2010. They were identified by morphological and molecular methods. The first one included traditional culture, slide culture, and microscopic examination after lactophenol cotton blue stain and KOH digestion. The second one was amplifying and sequencing the part of ITS and β-tubulin gene and aligned all the sequences in the GenBank, European Molecular Biology Laboratory nucleotide sequence database, and DNA Data Bank of Japan. Results Of the 56 Aspergillus flavus identified by morphological features, fifty-five isolates were identified as Aspergillus flavus and 1 isolates was Aspergillus parasiticus by the ITS and β-tubulin gene region sequence analysis. In the 37 Aspergillus fumigatus identified by morphological method, and all the 37 isolates were identified as species complex of Aspergillus fumigatus by the ITS region sequence analysis, but through the sequence analysis of β-tubulin gene region, thirty-five isolates were identified as Aspergillus. fumigatus and 2 were Aspergillus lentulus. Twenty-one isolates were identified as Aspergillus versicolor by morphological method, but 16 of them were identified as Aspergillus. versicolor and 5 can not be identified to species level by the ITS region sequence. And by comparative-sequence analysis of β-tubulin gene region, the 5 isolates were identified as Aspergillus sydowii,the other 16 isolates were Aspergillus. versilcolor. Ten isolates were identified as Aspergillus nidulans by morphological features, the ITS and β-tubulin gene region sequence analysis. Conclusions β-tubulin gene sequencing is more suitable for identifying Aspergillus, and could identify Aspergillus spp. to species level Sequences of ITS region could only identify Aspergillus spp. to species complex.     

心肌梗死患者药物溶栓治疗对窦性心率振荡的影响

目的观察心肌梗死（MI）患者在应用尿激酶溶栓后对窦性心率振荡（HRT）的影响。方法选择MI后接受溶栓治疗的40例（治疗组）及未采取溶栓治疗的23例（对照组）患者均接受24 h动态心电图检查,分别计算HRT的振荡初始（TO）和震荡斜率（TS）数据,比较两组之间的差异。结果治疗组TO较对照组明显降低（P〈0.05）,TS明显升高（P〈0.05）。结论溶栓治疗后患者的HRT现象趋于正常。     

机关公务员内脏肥胖饮食干预研究

目的探讨机关公务员日常膳食营养素供给量的合理性及对内脏肥胖的影响。方法将2015年1~4月在我院进行门诊体质分析检测的机关公务员300例随机分为观察组(150例)和对照组(150例)。观察组给予饮食控制和有氧运动,对照组常规饮食,6个月后观察BMI及内脏脂肪含量的变化。结果观察组与对照组相比,后者的BMI及内脏脂肪含量均较高(P0.05)。过多摄取脂肪、糖类和饮食及生活的不规律都是导致内脏肥胖的危险因素。结论加强相关健康教育可提高机关公务员的生活质量,降低与肥胖相关疾病的发生率。     

阻塞性睡眠呼吸暂停综合征与血清抵抗素的相关性研究

目的了解正常人、阻塞性睡眠呼吸暂停综合征（OSAS）患者血清抵抗素水平，探讨其与空腹血糖、体重指数的相关性．方法所有受试对象精确测量身高、体重，计算体重指数（BMI）．同步检测空腹血糖（FPC）、总胆固醇（TC）、甘油三脂（TG），采用酶联免疫吸附试验（ELISA）检测空腹血清抵抗素浓度．OSAS患者组经多导睡眠检测仪测定其睡眠呼吸暂停通气指数（AHI）及最低血氧饱和度（SaO2）．两组间比较用t检验，用Spearman和Pearson法进行相关分析．结果（1）OSAS患者组血清抵抗素、BMI、TC比正常对照组高，且差异有统计学意义（P〈0．05）；（2）血清抵抗素与BMI、FPG、TC正相关；（3）OSAS患者组BMI与AHI正相关、与SaO2负相关．结论OSAS患者血清抵抗素浓度升高；空腹血清抵抗素浓度与体重指数、空腹血糖、血清总胆固醇正相关，表明抵抗素在OSAS患者的脂、糖代谢中起一定作用．     

土壤氡与室内氡浓度关系的研究

目的了解土壤氡对底层房间的贡献.方法采用ERS1000和RAD7环境测氡仪测量土壤氡及析出率,根据析出率与室内氡关系公式计算了室内氡浓度的变化范围,对所得结果进行了实验验证.结果调查区域土壤氡浓度为(18 000±3 100)Bq·m-3;氡析出率为(8.15±5.55)Bq·m-2·s-1;混凝土地面的氡析出率为(0.72±0.19)Bq·m-2·s-1,普通混凝土结构房屋中氡浓度理论计算范围为11.5～42.4Bq·m-3.实际测量结果(18.9～40.6)Bq·m-3,预测值与实测结果一致.结论在土壤氡浓度低于20000Bq·m-3地区,采用传统建筑方式,不会引起室内氡浓度增高.     

血液透析＋血液灌流治疗百草枯中毒32例疗效观察

百草枯是一种应用广泛的除草剂,中毒病例多有发生.由于目前尚无有效的解毒剂,各地报道百草枯中毒后病死率为25%～76%.我院自1986年开展血液净化技术以来,先后收治了百草枯中毒患者32例,进行血液透析＋血液灌流或单纯的血液灌流,其效果没有其他类的药物中毒效果显著,现报告如下：     

鱼腥草注射液佐治老年肺部感染39例临床观察

目的：观察鱼腥草注射液佐治老年肺部感染的疗效及安全性。方法：60例老年（年龄〉60岁）肺部感染的患者随机分成治疗组和对照组，在常规治疗的基础上，治疗组则加用鱼腥草注射液治疗。对照组采用常规治疗。结果：治疗组第三天体温较对照组下降明显（P〈0．05）。第五天白细胞计数较对照组下降明显（P〈0．01），退热时间和治疗时间临床疗效明显优于对照组（P〈0．01）。结论：治疗老年肺部感染应用鱼腥草注射液可加快炎症吸收，缩短病程。