部分睑板全层切除联合提上睑肌缩短术矫正中重度上睑下垂

目的:探讨部分睑板全层切除联合提上睑肌缩短术矫正中重度上睑下垂的方法和疗效。方法:对15例(2007年～2011年)(19只眼)中重度上睑下垂患者行部分睑板全层切除联合提上睑肌缩短术。结果:术后随访6个月～3年,本组15例(19只眼)中重度上睑下垂均矫正满意(外观满意,弧度自然)。早期均有不同程度的眼睑闭合不全的情况,一般术后1～3个月内完全恢复,无并发症发生。结论:部分睑板全层切除联合提上睑肌缩短术,此手术操作简单,并发症少,而且疗效确切。     

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??Objective    To explore the application of digital technology to the treatment of dento-maxillofacial deformities. Methods    Twelve patients with dento-maxillofacial deformities were enrolled and DICOM data were reconstructed with 3D-CT of maxillary and mandible. The DICOM data were input into the software of Proplan CMF. We built digital skull model and 3D-printed skull model to perform surgical planning?? postoperative prediction and simulate operation. Clinical examinations of facial symmetry were performed 3 months later. Results    All the surgical plannings?? postoperative predictions and simulate operations of the twelve patients with dento-maxillofacial deformities were performed. And the orthognathic surgery was successfully. The patients were satisfied with the facial symmetry 3 months after operations?? with a satisfaction rate of 91.67%?? Conclusion    When using digital technology to perform surgical planning and simulate operation??the accuracy of surgeries is improved with satisfactory effect. So the digital technology has practical value in the treatment of dento-maxillofacial deformities.     

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??Objective    On the basis of this experiment in simulated clinical vascular compression of the trigeminal root??use the agar compression of trigeminal nerve root by 3D positioning to establish a new animal model of trigeminal neuralgia and relevant research. Methods    Adult male Sprague-Dawley rats were randomly divided into 2 groups??Experimental group??the rat head brain locator targeted to the trigeminal nerve root and 5% agar solution??10μL??was injected into the trigeminal nerve root by using miro syringe??Control group rats positioning micro syringe to the trigeminal nerve root injection of saline solution. Preoperative 1 d and postoperative 1??2??3??5??7??10??14??21??28??35??42 d respectively with behavioral observation of animals??Von Frey fiber mechanical stimulation reaction threshold determination in rats??use the ANOVA and T test for data statistics analysis. At the same time take the trigeminal nerve with HE and silver staining and trigeminal ganglion in the astrocytes GFAP immunefluorescence detection. Results    Experimental rat lateral mechanical stimulation reaction threshold operation gradually reduce and stabilize last about 30 days after surgery??P??0.05??. HE and argentophilic staining showed swelling of the nerve fibers??demyelinating changes??the surgical operation side trigeminal ganglion of rats in astrocytes increased GFAP expression. Conclusion    Agar compression in the rat trigeminal nerve root can establish a reliable and effective animal model for the future further research of etiology and treatment of TN provide a reliable and effective animal model.     

磁共振成像在甲状腺良恶性病变鉴别诊断中的价值研究

目的 为了进一步探究在良性、恶性甲状腺病变诊断过程中,磁共振成像技术具有实际的临床应用价值.方法 选取我院自2012年7月至2013年7月间收治的53名甲状腺病变患者的磁共振诊断资料,共进行61处病灶诊断,对比T1WI信号、T2WI信号、DWI信号对良性、恶性病变的指示作用,以及MRI影像结果对病变处的指示作用.结果 T1WI影像信号对良性病变结果指示等同或稍高,对恶性病变结果指示不均等或稍高;T2WI影像信号对良性病变结果指示均稍高.DWI影像结果指示性：b=150,则ADC=（2.392 ±0.413）;b=300,则ADC=（1.997 ±0.318）;b=500,则ADC=（1.241 ±0.311）.对甲状腺良性、恶性肿瘤的指示结果T1WI与T2WI影像信号无统计学差异性（P均＞0.05）,DWI影响结果具有统计学差异性（P＜0.05）.但T1WI与T2WI影响图形变化趋势具有一定渐变规律,具有极高指示作用.结论 对于良性、恶性甲状腺病变,磁共振影像学的检测结果具有极强的指示效果,每一种信号结果都可以作为定诊依据,在临床应用过程中意义重大,应该大力推广.     

儿童活体肝移植术后住院期间细菌感染的临床研究

目的 研究儿童活体肝移植术后细菌感染的常见病原菌种类、分布特征及耐药性.方法 回顾性分析41例儿童活体肝移植的临床资料,对受者术后住院期间的细菌感染发生率、感染发生时间、感染部位、病原菌种类和分布以及药敏试验结果进行总结.结果 41例肝移植受者中,有33例受者发生细菌感染69次,细菌感染发生率为80.5％(33/41).主要的感染部位依次是下呼吸道32例次(占46.6％)、腹腔16例次(占23.3％)及胆道11例次(占15.9％).共检出致病菌101株,其中革兰阴性菌(G-菌)占73.3％(74/101),超广谱β-内酰胺酶(ESBL)检出率为81.1％ (60/74);革兰阳性菌(G+菌)占26.7％(27/101),耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)检出率为59.3％(16/27),氨基糖苷类高耐药肠球菌(HLAR)检出率为11.1％(3/27).术后2周内检出致病菌72株(71.3％).常见致病菌为铜绿假单胞菌、表皮葡萄球菌和大肠埃希菌等.致病菌对β-内酰胺类加酶抑制剂和头孢类的耐药率超过60％,主要的产ESBL的G-菌对碳青霉烯类敏感,耐药率＜10％;碳青霉烯类药物亚胺培南/西司他丁、美罗培能对质粒介导的ESBL、染色体及质粒介导的头孢菌素酶(AmpC酶)均具有高度稳定性;铜绿假单胞菌对碳青霉烯类和儿科常用抗生素均高度耐药,仅对喹诺酮类敏感;凝固酶阴性葡萄球菌和肠球菌对万古霉素、利奈唑胺、奎奴普丁/达福普丁高度敏感.结论 肝移植术后细菌感染发生率高,耐药菌株检出率高,且具有多重耐药特点.有效地预防感染,术后早期确诊和合理选用抗生素是控制细菌感染的关键.     

压膜式保持器与 Hawley 保持器的临床应用效果比较

压膜式保持器和Hawley保持器是常用的两种活动式正畸保持器,两者在制作、临床应用、维护和使用方面各有优缺点。Hawley保持器制作相对复杂,体积大,但耐用、易调节;压膜式保持器制作简单,戴用舒适、美观,但易损坏。然而,最重要的是两者对不同错猞类型的保持效果也有差异,正畸医生应同时考虑矫治前后的牙列特征和患者的依从性,选择适合患者的保持器类型。     

分子放射生物学中几个探讨中的课题

分子生物学对放射生物学的很多方面有着决定性的影响。     

辐射防护剂与致敏剂的研究及两者相互关系

辐射化学防护研究,在这次国际会议中论文不多,在少数论文中也看不出任何新的进展,除了几篇复方研究和防护机理论文外;很少新的东西。另一方面,辐射致敏剂的论文却很多,而且有的学者论及致敏剂的关系,这一新动向值得注意。现将两方面工作及两者的关系简述如下。     

细胞工程与放射病防治

放射损伤的一个突出问题是造血组织的破坏,动物丧失了造血功能,从而产生各种严重症状,甚至导致死亡。     

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??Abstract??Objective To raise awareness of pulmonary artery sling??PAS??and to improve its early diagnosis and reduce misdiagnosis. Methods By analyzing the information of two cases?? evaluate the importance of echocardiography??MRI and enhanced + 3D CT in early diagnosis. Results These two patients had major clinical manifestations of recurring bucking and vomiting??and laryngeal stridor.One case was confirmed by Enhanced + 3D CT??and the another case was confirmed by echocardiography and Enhanced + 3D CT. Conclusions The infants who had clinical manifestations such as repeatedly bucking and vomiting??laryngeal stridor??pneumonia or respiratory tract infection??and who were treated unsatisfactorily should consider PAS.Echocardiography??enhanced + 3D CT and MRI play an important role in the diagnosis of PAS.