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991.
Suzana Carvalho Teixeira Pinto de Souza Kaline Cassiano de Araújo Joseane Ribeiro Barbosa Viviane Cancio Anderson Araújo Rocha 《Acta odontologica Scandinavica》2018,76(3):188-194
Objective: To evaluate the effect of different fluoride- and calcium- and/or phosphate-containing products on their ability to prevent enamel demineralization under pH cycling conditions.Material and methods: Enamel bovine specimens were assigned to the following groups: G1-MPP (MI Paste Plus, 0.2% NaF, Recaldent?, GC Corporation Tokyo, Japan); G2-FD (Crest? Cavity Protection, 0.243% NaF, Procter &; Gamble, USA); G3-CLP (Clinpro? 5000, 1.1% NaF, 3M ESPE, USA); and G4-CO (Control without fluoride, Silica-based dentifrice; Daudt Ltda, Brazil). The specimens were soaked in demineralizing solution for 6?h and remineralizing solution for 18?h alternatively for 10 days. The toothpaste was prepared with deionized water in a 1:3 ratio (w/v) for three minutes daily. The solutions were renewed every 48?h. After cycling, enamel changes were analysed by percentage change of SMH (%SMH) and energy-dispersive X-ray spectroscopy (EDS). The %SMH value observed for G3-CLP (2.9?±?39.2) was higher than that found in G4-CO (?13.0?±?20.7), G1-MPP (?8.9?±?20.9) and G2-FD (?3.9?±?27.1). The %SMH was similar for all treatment groups (one-way ANOVA and Tukey’s HSD; p?.05). The pH, Ca2+ and Ptotal in the remineralization solutions were not different among all groups (Kruskal–Wallis; p?.05). At 24?h, the Ca2+ concentration in the demineralization solution was significantly lower in G1-MPP. Ca2+ concentration increased in all groups after 48?h, except for G3-CLP. The EDX quantitative analysis showed that the atomic % of elements is lower level at G4-CO.Conclusions: The Clinpro? 5000 demonstrated having the most protective effect against demineralization; however, the % SMH was similar for all groups. 相似文献
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Maria Teresinha Gomes Casavechia Maria Valdrinez Campana Lonardoni Eneide Aparecida Sabaini Venazzi Paula Aline Zanetti Campanerut-Sá Hugo Rafael da Costa Benalia Matheus Felipe Mattiello Pedro Victor Lazaretti Menechini Carlos Aparecido dos Santos Jorge Juarez Vieira Teixeira 《Parasitology research》2016,115(6):2321-2329
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Rodrigues Alfredo M. V. Özak Argun Akif Silva Luis M. H. Boxshall Geoffrey Allan 《Parasitology research》2018,117(12):3843-3850
Parasitology Research - A new species of caligid copepod, Caligus mulli n. sp., is described based on specimens collected from surmullet Mullus surmuletus Linnaeus from Atlantic waters off the... 相似文献
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Gabriella de M. Abreu Roberta M. Tarantino Ana Carolina P. da Fonseca Ritiele B. de Souza Camila A.P.D. Soares Pedro H. Cabello Melanie Rodacki Lenita Zajdenverg Verônica M. Zembrzuski Mário Campos Junior 《European journal of medical genetics》2021,64(5):104194
Maturity-Onset Diabetes of the Young type 4 is a rare form of diabetes mellitus, caused by mutations in the PDX1 gene. However, only a few mutations in this gene have been associated as a cause of monogenic diabetes up to date. It makes difficult to create a clinical manifestation profile of this disease and, consequently, to improve the therapeutic management for these patients. Here we report a normal weight woman, diagnosed with diabetes mellitus at 27 years old, during her first pregnancy. At the time of the recruitment, she was 40 years old and had a body mass index of 23.9 kg/m2, glycated hemoglobin level of 9.6%, and fasting plasma glucose (FPG) of 254 mg/dL. She presented no diabetic complications and she was being treated with insulin. She reported a family history of diabetes mellitus characteristic of an autosomal dominant mode of inheritance. Molecular analysis of the PDX1 gene revealed the missense variant c.532G > A (p.(Glu178Lys)) segregating from the patient to her son, reported as diabetic. It was absent in her healthy daughter. The c.532G > A seems to be a rare variant, absent in human variants databases, and among 86 normoglycemic controls. Eight in silico algorithms classified this variant as probably pathogenic. Additionally, analysis of the evolutionary conservation showed the glutamic acid in the position 178 of PDX-1 protein as conserved among several species. Our findings reinforce the importance of screening rare MODY genes among families with suspicion of monogenic diabetes to help better understand the clinical manifestations of this disease. 相似文献