全文获取类型
收费全文 | 64036篇 |
免费 | 4754篇 |
国内免费 | 1775篇 |
专业分类
耳鼻咽喉 | 839篇 |
儿科学 | 1196篇 |
妇产科学 | 2217篇 |
基础医学 | 8064篇 |
口腔科学 | 1163篇 |
临床医学 | 6850篇 |
内科学 | 11983篇 |
皮肤病学 | 1190篇 |
神经病学 | 3976篇 |
特种医学 | 2616篇 |
外国民族医学 | 6篇 |
外科学 | 8537篇 |
综合类 | 4209篇 |
现状与发展 | 7篇 |
一般理论 | 11篇 |
预防医学 | 3519篇 |
眼科学 | 1419篇 |
药学 | 5357篇 |
21篇 | |
中国医学 | 1680篇 |
肿瘤学 | 5705篇 |
出版年
2023年 | 528篇 |
2022年 | 1328篇 |
2021年 | 2166篇 |
2020年 | 1316篇 |
2019年 | 1628篇 |
2018年 | 2006篇 |
2017年 | 1521篇 |
2016年 | 1576篇 |
2015年 | 2345篇 |
2014年 | 2929篇 |
2013年 | 3406篇 |
2012年 | 4836篇 |
2011年 | 4707篇 |
2010年 | 2998篇 |
2009年 | 2623篇 |
2008年 | 3555篇 |
2007年 | 3547篇 |
2006年 | 3391篇 |
2005年 | 3130篇 |
2004年 | 2827篇 |
2003年 | 2712篇 |
2002年 | 2350篇 |
2001年 | 1843篇 |
2000年 | 1610篇 |
1999年 | 1336篇 |
1998年 | 553篇 |
1997年 | 457篇 |
1996年 | 417篇 |
1995年 | 380篇 |
1994年 | 349篇 |
1993年 | 243篇 |
1992年 | 712篇 |
1991年 | 582篇 |
1990年 | 531篇 |
1989年 | 484篇 |
1988年 | 421篇 |
1987年 | 424篇 |
1986年 | 355篇 |
1985年 | 295篇 |
1984年 | 229篇 |
1983年 | 191篇 |
1982年 | 114篇 |
1981年 | 122篇 |
1980年 | 99篇 |
1979年 | 205篇 |
1978年 | 161篇 |
1977年 | 103篇 |
1976年 | 110篇 |
1975年 | 102篇 |
1974年 | 99篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
991.
992.
993.
Diabetes is a life-long illness condition that many diabetic patients end up with related complications resulted largely from lacking of proper supports. The success of diabetes care relies mainly on patient’s daily self-care activities and care providers’ continuous support. However, the self-care activities are socially bounded with patient’s everyday schedules that can easily be forgotten or neglected and the care support from providers has yet been fully implemented. This study develops a Web 2.0 diabetes care support system for patients to integrate required self-care activities with different context in order to enhance patient’s care knowledge and behavior adherence. The system also supports care managers in a health service center to conduct patient management through collecting patient’s daily physiological information, sharing care information, and maintaining patient-provider relationships. After the development, we evaluate the acceptance of the system through a group of nursing staffs. 相似文献
994.
Zhi‐qing Li Kai Liu Ji‐cheng Duan Zhe Li Chang‐qing Su Jia‐he Yang 《Hepatology research》2013,43(1):72-83
Aim: There is no clear consensus on the optimal timing of surgical resection for synchronous colorectal liver metastases (SCLM). This study is a meta‐analysis of the available evidence. Methods: Systematic review and meta‐analysis of trials comparing outcomes following simultaneous resection with staged resection for SCLM published from 1990 to 2010 in PubMed, Embase, Ovid and Medline. Pooled odds ratios (OR) or weighted mean differences (WMD) with 95% confidence intervals (95% CI) were calculated using either the fixed effects or random effects model. Results: Nineteen non‐randomized controlled trials (NRCT) studies were included in this analysis. These studies included a total of 2724 patients: 1116 underwent simultaneous resection and 1608 underwent staged resection. Meta‐analysis showed that shorter hospital stay (P < 0.001) and lower total complication rate (P < 0.001) were observed in patients undergoing simultaneous resection group. The overall survival rate in the simultaneous resection group did not statistically differ with that in the staged resection group at 1 year (P = 0.13), 3 years (P = 0.26), 5 years (P = 0.38), as well as the 1, 3 and 5 years disease‐free survival rates (respectively, P = 0.55; P = 0.16; P = 0.12). No significant difference was noted between the two groups in terms of mortality (P = 0.16), intraoperative blood loss (P = 0.06) and recurrence (P = 0.47). Conclusion: Simultaneous resection is safe and efficient in the treatment of patients with SCLM while avoiding a second laparotomy. In selected patients, simultaneous resection might be considered as the preferred approach. However, the findings have to be carefully interpreted due to the lower level of evidence and the existence of heterogeneity. 相似文献
995.
Shu-Hui Cheng Chi-Chen Shih Yen-Kuang Yang Kow-Tong Chen Yun-Hsuan Chang Yi-Ching Yang 《The Kaohsiung journal of medical sciences》2013,29(2):100-105
Premenstrual syndrome (PMS) can impact an individual's interpersonal relationships, social interactions, productivity, lifestyle, school performance and emotional well-being. This study was designed to explore the factors associated with PMS in new female university students in Taiwan. The test battery included a self-administered structured questionnaire, the five-item brief symptoms rating scale, the Pittsburgh Sleep Quality Index and the Chinese Premenstrual Symptom Questionnaire. Additionally, details of the participants' lifestyles and family and personal histories of physical illness were recorded. Serum lipids were also measured. Of all the participants (N = 1699), 39.85% were defined as having PMS. Using logistical regression analysis, we found a positive relationship between PMS and consuming more foods containing egg yolk, greater alcohol intake, poorer sleep quality, higher likelihood of psychiatric morbidity, family history of dyslipidemia, and a higher serum cholesterol level. The results show that PMS is prevalent among new female university students and that lifestyle and nutritional/metabolic factors may play a role in this disorder. 相似文献
996.
Kwok-Chiu Chang Wing-Wai Yew Cheuk-Ming Tam Chi-Chiu Leung 《Antimicrobial agents and chemotherapy》2013,57(9):4097-4104
It is often necessary to include WHO group 5 drugs in the treatment of extensively drug-resistant tuberculosis (XDR-TB) and fluoroquinolone-resistant multidrug-resistant tuberculosis (MDR-TB). As clinical evidence about the use of group 5 drugs is scarce, we conducted a systematic review using published individual patient data. We searched PubMed and OvidSP through 7 April 2013 for publications in English to assemble a cohort with fluoroquinolone-resistant MDR-TB treated with group 5 drugs. Favorable outcome was defined as sputum culture conversion, cure, or treatment completion in the absence of death, default, treatment failure, or relapse. A cohort of 194 patients was assembled from 20 articles involving 12 geographical regions. In descending order of frequency, linezolid was used in treatment of 162 (84%) patients, macrolides in 84 (43%), clofazimine in 65 (34%), amoxicillin with clavulanate in 56 (29%), thioridazine in 18 (9%), carbapenem in 16 (8%), and high-dose isoniazid in 16 (8%). Cohort analysis with robust Poisson regression models and random-effects meta-analysis similarly suggested that linezolid use significantly increased the probability (95% confidence interval) of favorable outcome by 57% (10% to 124%) and 55% (10% to 121%), respectively. Defining significant associations by risk ratios ≥ 1.2 or ≤ 0.9, neither cohort analysis nor meta-analysis demonstrated any significant add-on benefit from the use of other group 5 drugs with respect to outcome for patients treated with linezolid, although selection bias might have led to underestimation of their effects. Our findings substantiated the use of linezolid in the treatment of XDR-TB or fluoroquinolone-resistant MDR-TB and call for further studies to evaluate the roles of other group 5 drugs. 相似文献
997.
998.
999.
Dae Chul Suh Sung-Tae Park Tack Sun Oh Sang-Ok Park Ok Kyun Lim Soonchan Park Chang Woo Ryu Deok Hee Lee Young Bae Ko Sang-Wook Lee Kyunghwan Yoon Jong Sung Kim 《Korean journal of radiology》2011,12(4):515-518
The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis. We have modeled the high wall shear stress (WSS) in a severe M1 stenosis. The high WSS in the systolic phase of the cardiac cycle was well-correlated with a thick fibrous cap atheroma with enhancement, as was determined using high-resolution plaque imaging techniques in a severe stenosis of the middle cerebral artery. 相似文献
1000.