Comparisons of needs, need responses, and need response satisfaction of mothers of infants in neonatal intensive care units

Providing nursing care to meet the needs of mothers may be unsuccessful because most nurses perceive and prioritize maternal needs differently from how mothers do. In this study, 140 mothers of infants in each neonatal intensive care unit of three hospitals in southern Thailand were interviewed using questionnaires on maternal needs, need responses, and need response satisfaction. Significant differences in mean total scores and mean subscale scores of needs, need responses, and need response satisfaction were found among the three groups of mothers. Significant differences in mean differences of total needs, need responses, and need response satisfaction were found when comparing mothers in each group. The mean rankings of maternal needs, need responses, and need response satisfaction were identified. This study supported the idea of individualized maternal needs and priorities. In providing effective nursing care to meet the needs and satisfaction of mothers, nurses should be concerned with the needs of individuals, their responses to those needs, and need response satisfaction because the satisfaction of these needs is essential for infant well-being.     

HPV genotyping in adenocarcinoma of the uterine cervix in Thailand

Objective

To determine the distribution of human papillomavirus (HPV) genotypes in cervical adenocarcinoma in Thailand and to evaluate the clinicopathologic characteristics associated with common HPV genotypes.

Methods

Formalin-fixed, paraffin-embedded tissues from 150 patients with adenocarcinoma were collected from 4 areas of Thailand. Infection with HPV was detected by nested polymerase chain reaction (PCR) with primers MY09/11 and GP5 +/6 +. Genotyping was performed using a linear array assay, followed by type-specific PCR targeting the E6/E7 regions of HPV-16, HPV-18, and HPV-52 if the linear array test was negative.

Results

Human papillomavirus DNA was detected in 145 (97%) adenocarcinomas (132 single infections; 11 multiple infections; 2 tumors with undetermined HPV type). Genotype 18 was most common (66%), followed by HPV-16 (30%) and HPV-45 (3%). Infection with only HPV-16 and/or HPV-18 accounted for 88% of the HPV-positive tumors. Patients with HPV-18 infection had a younger age (P = 0.009) and higher tumor grade (P < 0.001) than patients with HPV-16 infection.

Conclusion

The HPV detection rate in cervical adenocarcinomas in Thailand is high. The predominant genotype is HPV-18, being twice as common as HPV-16. Genotype variations are associated with patient age and tumor grade. Vaccination against HPV-16/HPV-18 might prevent almost 90% of adenocarcinomas.