全文获取类型
收费全文 | 39211篇 |
免费 | 2273篇 |
国内免费 | 107篇 |
专业分类
耳鼻咽喉 | 479篇 |
儿科学 | 1475篇 |
妇产科学 | 692篇 |
基础医学 | 5264篇 |
口腔科学 | 822篇 |
临床医学 | 2822篇 |
内科学 | 9871篇 |
皮肤病学 | 1176篇 |
神经病学 | 3879篇 |
特种医学 | 1027篇 |
外科学 | 5210篇 |
综合类 | 170篇 |
一般理论 | 11篇 |
预防医学 | 3310篇 |
眼科学 | 600篇 |
药学 | 2338篇 |
中国医学 | 140篇 |
肿瘤学 | 2305篇 |
出版年
2023年 | 263篇 |
2022年 | 381篇 |
2021年 | 1159篇 |
2020年 | 559篇 |
2019年 | 1047篇 |
2018年 | 1527篇 |
2017年 | 943篇 |
2016年 | 943篇 |
2015年 | 989篇 |
2014年 | 1149篇 |
2013年 | 1674篇 |
2012年 | 2792篇 |
2011年 | 3018篇 |
2010年 | 1634篇 |
2009年 | 1269篇 |
2008年 | 2404篇 |
2007年 | 2526篇 |
2006年 | 2361篇 |
2005年 | 2337篇 |
2004年 | 2210篇 |
2003年 | 1917篇 |
2002年 | 1885篇 |
2001年 | 1100篇 |
2000年 | 1311篇 |
1999年 | 963篇 |
1998年 | 246篇 |
1997年 | 176篇 |
1996年 | 157篇 |
1995年 | 121篇 |
1994年 | 95篇 |
1993年 | 80篇 |
1992年 | 353篇 |
1991年 | 267篇 |
1990年 | 277篇 |
1989年 | 184篇 |
1988年 | 143篇 |
1987年 | 129篇 |
1986年 | 139篇 |
1985年 | 114篇 |
1984年 | 81篇 |
1983年 | 63篇 |
1982年 | 35篇 |
1979年 | 38篇 |
1975年 | 30篇 |
1974年 | 54篇 |
1973年 | 56篇 |
1972年 | 41篇 |
1971年 | 40篇 |
1970年 | 40篇 |
1969年 | 38篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
101.
Two new cases of prostatic blue nevus are studied with routine histological, immunohistochemical and ultrastructural methods. Both cases showed a chronic lower urinary tract obstruction due to a benign prostatic hyperplasia with spindle-shaped stromal cells loaded with melanin pigment. These cells were positive for S-100 and negative for HMB-45 antibodies, being, to the best of our knowledge, the first time that this antibody has been tested in prostatic pigmented lesions. The electron-microscopy study was performed in the first case, confirming the nature of these pigmented cells as melanocytes derived from the neural crest showing melanosomes in all the stages of differentiation and without complete basal cell membrane. The histogenesis of pigmented lesions of the prostate and the differences between blue nevus and melanosis are discussed, and the literature is reviewed. 相似文献
102.
J L Martínez Sande A Amaro Cendón E Blanco Labrador M Pérez Rodríguez A Sánchez Prieto C Iglesias Carre?o M Gil de la Pe?a 《Revista espa?ola de cardiología》1992,45(8):545-548
A 32-year old woman, with endocarditis caused by Streptococcus mitis, and systolic murmur is presented. The Doppler examination was found a systolic gradient of 150 mmHg. Aortography showed a multiple membranous supravalvular aortic stenosis, with aneurysmal dilatation of the left main coronary artery and circumflex artery, associated with bicuspid aortic valve and mild aortic insufficiency. The patient died suddenly by cardiac arrest in stand by to cardiac surgery. Anatomic comprobation was not possible. The coronary artery anomalies associated with the supravalvular aortic stenosis syndrome are reviewed. 相似文献
103.
Camila Oliveira Rodini Flávia Sirotheau Corrêa Pontes Hélder Ant?nio Rebelo Pontes Paulo Sérgio da Silva Santos Marina Gallottini Magalh?es Décio Santos Pinto 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(4):e50-e55
Leiomyosarcoma of the oral cavity is a very rare tumor associated with aggressive clinical behavior and low survival. In this paper, we report 2 cases of leiomyosarcoma, affecting the gingival mucosa of a 54-year-old female and the maxillary bone of a 63-year-old male. Histologically, the tumors were composed of variably oriented fascicles of spindle-shaped cells with cigar-shaped nuclei and eosinophilic cytoplasm. The lesions were treated by surgical resection. Immunoreactivity to anti-vimentin, anti-smooth muscle actin, anti-desmin, anti-laminin, and anti-muscle-specific actin antibodies were found; conversely, the tumor cells were negative for anti-S100 and AE1/AE3 proteins. This report emphasizes the role of immunohistochemical study for correct diagnosis of leiomyosarcoma. 相似文献
104.
Alfredo Avellaneda Fernández álvaro Pérez Martín Maravillas Izquierdo Martínez Mar Arruti Bustillo Francisco Javier Barbado Hernández Javier de la Cruz Labrado Rafael Díaz-Delgado Pe?as Eduardo Gutiérrez Rivas Cecilia Palacín Delgado José Ramón Ramón Giménez Javier Rivera Redondo 《Atencion primaria / Sociedad Espa?ola de Medicina de Familia y Comunitaria》2009,41(10):e1-e5
105.
Atilio Migues MD Gaston Slullitel MD Anibal Vescovo MD Felipe Droblas MD Marina Carrasco MD Hugo Perrin Turenne MD 《The Journal of foot and ankle surgery》2005,44(5):1043-357
The majority of foot and ankle operations are performed on an outpatient basis and often under some form of regional anesthesia. In this prospective, randomized study of 51 patients undergoing elective unilateral forefoot procedures, we compared 2 different anesthetic techniques: the peripheral foot blockade and the popliteal sciatic nerve block. Variables assessed included the quality of surgical anesthesia, postoperative analgesia, and the incidence of postoperative complications. The anesthesia was classified as effective if it was the sole anesthetic technique for the forefoot surgery. We found successful results in both groups: 92% in the foot block group and 96% in the popliteal block group. Analysis of time required to perform the anesthetic procedure showed a significant difference between the 2 groups, with foot block being considerably faster (14.3 minutes vs 19.2 minutes for popliteal block) (P = .0078). Foot block patients demonstrated 10.96 hours of analgesia, whereas popliteal block patients exhibited 14.32 hours (P = .132). With a mean follow-up of 5.7 months, we did not find anesthesia-related complications in any of the patients. Both techniques showed a high level of safety and efficacy, with no significant difference detected between them. Our patients showed a high rate of satisfaction with both procedures (96% for foot block patients and 96.1% for popliteal block patients) and reported a good discharge disposition. These data show that both procedures are safe and effective anesthetic techniques and well suited to forefoot ambulatory surgery. 相似文献
106.
Pedro Antonio Martínez-Carpio Miguel Ángel Navarro Moreno 《Clinical & translational oncology》2003,5(4):184-191
Resumen La técnica del cultivo celular es la que ha permitido conocer el comportamientoin vitro de las células cancerosas. En esta revisión pretendemos introducir las peculiaridades básicas del cultivo celular, referido
especialmente a líneas cancerosas mamarias, relacionar el origen de las líneas celulares más utilizadas en la investigación
de este cáncer, mencionar las técnicas de laboratorio que pueden aplicarse sobre estos cultivos y ejemplificar la utilidad
de las mismas, tomando como modelo diversos trabajos que estudian los efectos del factor de crecimiento epidérmico sobre líneas
celulares hormonoindependientes de cáncer de mama.
相似文献
107.
E Garza González E Giasi González M A Martínez Vázquez G I Pérez Pérez G M González H J Maldonado Garza F J Bosques Padilla 《Revista española de enfermedades digestivas》2007,99(2):71-75
OBJECTIVE: to assess the efficacy of rabeprazole (RPZ), amoxicillin (Am), and clarithromycin (Cla) (7 vs. 14 days) in the eradication of H. pylori, and to determine the effect of strain-specific antibiotic resistance and host CYP2C19 status. MATERIAL AND METHODS: first, we determined the CYP2C19 status of 100 healthy subjects to establish a sample size for the clinical trial. Then, 59 H. pylori-infected patients were randomized to receive RPZ (20 mg daily) plus Cla (500 mg b.d.) and Am (1,000 mg b.d.) for 7 vs. 14 days. The MIC for Am and Cla were determined using the agar dilution method. The CYP2C19 genotype was determined by the PCR-RFLP method. RESULTS: In the per-protocol analysis (PP) eradication rates were 89.7 and 72% for the 7- and 14-day groups (p = 0.159). In the intention to-treat analysis (ITT) eradication rates were 86.7 and 62.1% in the 7- and 14-day groups, respectively (p = 0.06).None of the strains was resistant to Am, and 4 strains were resistant to Cla: 3 (11.1%) in the 14-day group and 1 (4%) in the 7-day group. Neither strain-specific antibiotic resistance nor host CYP2C19 status influenced eradication rates. CONCLUSIONS: both 7- and 14-day therapies were effective for H. pylori eradication. Strain resistance and CYP2C19 status do not seem to influence eradication rates in the studied population. 相似文献
108.
Miguel Marcos Alex Soriano José A Martínez Josep Mensa 《Clinical infectious diseases》2007,45(10):1401; author reply 1401-1401; author reply 1402
109.
110.