全文获取类型
收费全文 | 53908篇 |
免费 | 8297篇 |
国内免费 | 1155篇 |
专业分类
耳鼻咽喉 | 973篇 |
儿科学 | 1015篇 |
妇产科学 | 1062篇 |
基础医学 | 5441篇 |
口腔科学 | 3139篇 |
临床医学 | 7558篇 |
内科学 | 10412篇 |
皮肤病学 | 1253篇 |
神经病学 | 4168篇 |
特种医学 | 2574篇 |
外国民族医学 | 5篇 |
外科学 | 7522篇 |
综合类 | 2552篇 |
现状与发展 | 19篇 |
一般理论 | 9篇 |
预防医学 | 4514篇 |
眼科学 | 1172篇 |
药学 | 3636篇 |
15篇 | |
中国医学 | 1069篇 |
肿瘤学 | 5252篇 |
出版年
2024年 | 221篇 |
2023年 | 1493篇 |
2022年 | 1443篇 |
2021年 | 2128篇 |
2020年 | 2055篇 |
2019年 | 1413篇 |
2018年 | 2379篇 |
2017年 | 2121篇 |
2016年 | 2568篇 |
2015年 | 3063篇 |
2014年 | 3768篇 |
2013年 | 4331篇 |
2012年 | 3578篇 |
2011年 | 3635篇 |
2010年 | 3039篇 |
2009年 | 3348篇 |
2008年 | 2716篇 |
2007年 | 2356篇 |
2006年 | 2306篇 |
2005年 | 2021篇 |
2004年 | 1552篇 |
2003年 | 1335篇 |
2002年 | 1117篇 |
2001年 | 1077篇 |
2000年 | 1002篇 |
1999年 | 956篇 |
1998年 | 761篇 |
1997年 | 702篇 |
1996年 | 699篇 |
1995年 | 547篇 |
1994年 | 436篇 |
1993年 | 362篇 |
1992年 | 334篇 |
1991年 | 323篇 |
1990年 | 275篇 |
1989年 | 246篇 |
1988年 | 210篇 |
1987年 | 201篇 |
1986年 | 170篇 |
1985年 | 140篇 |
1984年 | 109篇 |
1983年 | 126篇 |
1982年 | 112篇 |
1981年 | 88篇 |
1980年 | 65篇 |
1979年 | 63篇 |
1978年 | 50篇 |
1977年 | 59篇 |
1976年 | 44篇 |
1974年 | 41篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
991.
992.
Hollis Day MD MS Elizabeth Eckstrom MD MPH Sei Lee MD MCR Heidi Wald MD MPH Steven Counsell MD Eugene Rich MD 《Journal of general internal medicine》2014,29(6):911-914
As the population ages, the quantity and complexity of comorbidities only increases in the primary care setting. Health systems strive to improve quality of care and enhance cost savings, but current administrative and payment systems do not easily support the implementation of existing evidence and best practices for multimorbid adults in most primary care offices. This perspectives piece sets forth a research agenda in the area of implementation science at the intersection of geriatrics and general internal medicine. We challenge academic medical centers, medical societies, journals, and funders to actively value and support investigation in this area as much as traditional research pathways. 相似文献
993.
994.
“Falls prevention among older people and care providers: protocol for an integrative review”
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Carmen de la Cuesta‐Benjumea MSc Phd RGN Maria Adriana Henriques MSc PhD RN Eva Abad‐Corpa MSc PhD RN Brenda Roe MSc PhD RGN María Isabel Orts‐Cortés MSc PhD RN Beatriz Lidón‐Cerezuela MSc PhD RN Almudena Avendaño‐Céspedes MS Clinical research RN José Luís Oliver‐Carbonell MS RN 《Journal of advanced nursing》2017,73(7):1722-1734
995.
996.
Dynamic contrast‐enhanced MRI of nasopharyngeal carcinoma: A preliminary study of the correlations between quantitative parameters and clinical stage
下载免费PDF全文
![点击此处可从《Journal of magnetic resonance imaging : JMRI》网站下载免费的PDF全文](/ch/ext_images/free.gif)
997.
998.
999.
ABSTRACT: BACKGROUND: Allergic skin inflammation such as atopic dermatitis (AD), which is characterized by pruritus and inflammation, is regulated partly through the activity of regulatory T cells (Tregs). Tregs play key roles in the immune response by preventing or suppressing the differentiation, proliferation and function of various immune cells, including CD4+ T cells. Recent studies report that fermentation has a tremendous capacity to transform chemical structures or create new substances, and the omega-3 polyunsaturated fatty acids (n-3 PUFAs) in fish oil can reduce inflammation in allergic patients. The beneficial effects of natural fish oil (NFO) have been described in many diseases, but the mechanism by which fermented fish oil (FFO) modulates the immune system and the allergic response is poorly understood. In this study, we produced FFO and tested its ability to suppress the allergic inflammatory response and to activate CD4+CD25+Foxp3+ Tregs. RESULTS: The ability of FFO and NFO to modulate the immune system was investigated using a mouse model of AD. Administration of FFO or NFO in the drinking water alleviated the allergic inflammation in the skin, and FFO was more effective than NFO. FFO treatment did increase the expression of the immune-suppressive cytokines TGF-beta and IL-10. In addition, ingestion of FFO increased Foxp3 expression and the number of CD4+CD25+Foxp3+ Tregs compared with NFO. CONCLUSIONS: These results suggest that the anti-allergic effect of FFO is associated with enrichment of CD4+CD25+Foxp3+ T cells at the inflamed sites and that FFO may be effective in treating the allergic symptoms of AD. 相似文献
1000.