全文获取类型
收费全文 | 6326篇 |
免费 | 341篇 |
国内免费 | 39篇 |
专业分类
耳鼻咽喉 | 112篇 |
儿科学 | 253篇 |
妇产科学 | 318篇 |
基础医学 | 605篇 |
口腔科学 | 277篇 |
临床医学 | 519篇 |
内科学 | 1266篇 |
皮肤病学 | 85篇 |
神经病学 | 321篇 |
特种医学 | 242篇 |
外国民族医学 | 7篇 |
外科学 | 1144篇 |
综合类 | 163篇 |
一般理论 | 2篇 |
预防医学 | 426篇 |
眼科学 | 127篇 |
药学 | 501篇 |
中国医学 | 41篇 |
肿瘤学 | 297篇 |
出版年
2023年 | 52篇 |
2022年 | 135篇 |
2021年 | 214篇 |
2020年 | 145篇 |
2019年 | 179篇 |
2018年 | 227篇 |
2017年 | 147篇 |
2016年 | 170篇 |
2015年 | 184篇 |
2014年 | 247篇 |
2013年 | 334篇 |
2012年 | 454篇 |
2011年 | 423篇 |
2010年 | 274篇 |
2009年 | 253篇 |
2008年 | 320篇 |
2007年 | 359篇 |
2006年 | 364篇 |
2005年 | 352篇 |
2004年 | 261篇 |
2003年 | 256篇 |
2002年 | 202篇 |
2001年 | 91篇 |
2000年 | 80篇 |
1999年 | 75篇 |
1998年 | 64篇 |
1997年 | 49篇 |
1996年 | 53篇 |
1995年 | 38篇 |
1994年 | 33篇 |
1993年 | 26篇 |
1992年 | 38篇 |
1991年 | 45篇 |
1990年 | 49篇 |
1989年 | 45篇 |
1988年 | 50篇 |
1987年 | 51篇 |
1986年 | 37篇 |
1985年 | 26篇 |
1984年 | 24篇 |
1983年 | 22篇 |
1980年 | 16篇 |
1979年 | 17篇 |
1977年 | 23篇 |
1976年 | 16篇 |
1974年 | 15篇 |
1973年 | 18篇 |
1972年 | 17篇 |
1970年 | 17篇 |
1969年 | 18篇 |
排序方式: 共有6706条查询结果,搜索用时 15 毫秒
81.
82.
Nihat?KarakoyunluEmail author Goksel?Goktug Nevzat?Can??ener Kursad?Zengin Ismail?Nalbant Ufuk?Ozturk Ugur?Ozok Abdurrahim?Imamoglu 《Urological research》2015,43(3):283-287
The aim of the study was to compare percutaneous nephrolithotomy (PCNL) and staged retrograde flexible ureteroscopy (FURS) methods used in the treatment of kidney stones of 2 cm or more in diameter. The study comprised a total of 60 patients with a diagnosis of kidney pelvic stones more than 2 cm in diameter, for whom surgery was planned between January 2013 and January 2014. The patients were randomly allocated to two groups as staged retrograde FURS (Group A) and PCNL (Group B). Comparison of the groups was made with respect to operating time, number of procedures, total treatment time, length of hospital stay, stone-free rates and complications according to the Clavien–Dindo classification. In Group A, the total operating time of multiple sessions was 114.46 min. In Group B, a single session of PCNL was applied to all patients and the mean operating time was 86.8 min (p = 0.014). Mean total treatment time was 2.01 weeks in Group A and 1 week in Group B (p < 0.01). The mean total hospitalization time was 3.66 days in Group A and 3.13 days in Group B (p = 0.037). At the end of the sessions, clinically insignificant residual fragments were observed in ten patients of Group A and one patient of Group B (p = 0.03). No statistically significant difference was determined between the groups in terms of stone-free rates or complications. Although current technology with FURS is effective on large kidney stones, it has no superiority to PCNL due to the need for multiple sessions and long treatment time. 相似文献
83.
84.
85.
86.
Cytomegalovirus colitis in a patient with Behcet’s disease receiving tumor necrosis factor alpha inhibitory treatment 总被引:1,自引:0,他引:1
Sari I Birlik M Gonen C Akar S Gurel D Onen F Akkoc N 《World journal of gastroenterology : WJG》2008,14(18):2912-2914
Anti-tumor necrosis factor alpha (TNF-α) inhibitors are effective in the treatment of various inflammatory rheumatic conditions. Increased risks of serious infections are the major issues concerning the long-term safety of these agents. We present a case of a young male Behcet’s patient whose disease was complicated by cytomegalovirus (CMV) colitis. Colitis started 10 d after the third Infliximab dose and responded to the cessation of TNF blocking treatment and administration of ganciclovir. Tumor necrosis factor alpha and interferon gamma act at several levels in combating viral infections.CMV infections should be kept in mind and included in the differential diagnosis of severe gastrointestinal symptoms in patients receiving anti-TNF agents. 相似文献
87.
88.
Kanchan Ajbani Shou-Yean Grace Lin Camilla Rodrigues Duylinh Nguyen Francine Arroyo Janice Kaping Lynn Jackson Richard S. Garfein Donald Catanzaro Kathleen Eisenach Thomas C. Victor Valeru Crudu Maria Tarcela Gler Nazir Ismail Edward Desmond Antonino Catanzaro Timothy C. Rodwell 《Antimicrobial agents and chemotherapy》2015,59(1):414-420
Reliable molecular diagnostics, which detect specific mutations associated with drug resistance, are promising technologies for the rapid identification and monitoring of drug resistance in Mycobacterium tuberculosis isolates. Pyrosequencing (PSQ) has the ability to detect mutations associated with first- and second-line anti-tuberculosis (TB) drugs, with the additional advantage of being rapidly adaptable for the identification of new mutations. The aim of this project was to evaluate the performance of PSQ in predicting phenotypic drug resistance in multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) clinical isolates from India, South Africa, Moldova, and the Philippines. A total of 187 archived isolates were run through a PSQ assay in order to identify M. tuberculosis (via the IS6110 marker), and to detect mutations associated with M/XDR-TB within small stretches of nucleotides in selected loci. The molecular targets included katG, the inhA promoter and the ahpC-oxyR intergenic region for isoniazid (INH) resistance; the rpoB core region for rifampin (RIF) resistance; gyrA for fluoroquinolone (FQ) resistance; and rrs for amikacin (AMK), capreomycin (CAP), and kanamycin (KAN) resistance. PSQ data were compared to phenotypic mycobacterial growth indicator tube (MGIT) 960 drug susceptibility testing results for performance analysis. The PSQ assay illustrated good sensitivity for the detection of resistance to INH (94%), RIF (96%), FQ (93%), AMK (84%), CAP (88%), and KAN (68%). The specificities of the assay were 96% for INH, 100% for RIF, FQ, AMK, and KAN, and 97% for CAP. PSQ is a highly efficient diagnostic tool that reveals specific nucleotide changes associated with resistance to the first- and second-line anti-TB drug medications. This methodology has the potential to be linked to mutation-specific clinical interpretation algorithms for rapid treatment decisions. 相似文献
89.