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41.
作者对核糖体现有的制备方法进行了部分改进,从黄疸出血群赖型017株钩体中成功地制备了核糖体提取物。该提取物经SPA-ELISA 证实具有免疫原性,对40只受试豚鼠的保护试验结果表明,核糖体提取物对同型毒株的攻击具有明显的保护作用;结果还证明核糖体提取物能诱导机体的体液免疫反应。 相似文献
42.
43.
Andrea Frudinger Research Registrar Clive I. Bartram Consultant John A. D. Spencer Consultant Michael A. Kamm Consultant 《BJOG : an international journal of obstetrics and gynaecology》1997,104(9):1009-1013
Objective To assess the relation between perineal inspection and sphincter integrity in parous women.
Design Prospective observational study.
Setting District general hospital.
Population Fifty-seven consecutive parous women attending a gynaecology clinic for problems unrelated to the pelvic floor.
Methods A detailed history of bowel function and mode of delivery obtained; the perineum inspected to determine the presence and position of scarring, and anal endosonography performed.
Results In 19 women with an intact perineum on inspection, endosonography showed perineal scarring in five, with both perineal and sphincter scarring in three. Four had urge faecal incontinence. Three patients had a perineal tear only on inspection, but this group was too small for analysis and was discounted. Nine had an episiotomy scar only. Endosonography demonstrated perineal scarring in four, and combined perineal and sphincter scarring in two; one woman in this group had urge faecal incontinence. Twenty-six women had episiotomy and perineal tears on inspection. Endosonography revealed underlying perineal scarring in five women, with combined perineal and sphincter scarring in 14; six women in this group had urge faecal incontinence and one passive incontinence for flatus. Sonographically the scarring was anterior and circumferential rather than radial, and mostly left-sided, whereas on inspection episiotomy and perineal scarring were right sided.
Conclusions A normal perineum on clinical examination does not exclude underlying sphincter damage. The incidence of sphincter damage increases significantly when an episiotomy scar is associated with a perineal tear. 相似文献
Design Prospective observational study.
Setting District general hospital.
Population Fifty-seven consecutive parous women attending a gynaecology clinic for problems unrelated to the pelvic floor.
Methods A detailed history of bowel function and mode of delivery obtained; the perineum inspected to determine the presence and position of scarring, and anal endosonography performed.
Results In 19 women with an intact perineum on inspection, endosonography showed perineal scarring in five, with both perineal and sphincter scarring in three. Four had urge faecal incontinence. Three patients had a perineal tear only on inspection, but this group was too small for analysis and was discounted. Nine had an episiotomy scar only. Endosonography demonstrated perineal scarring in four, and combined perineal and sphincter scarring in two; one woman in this group had urge faecal incontinence. Twenty-six women had episiotomy and perineal tears on inspection. Endosonography revealed underlying perineal scarring in five women, with combined perineal and sphincter scarring in 14; six women in this group had urge faecal incontinence and one passive incontinence for flatus. Sonographically the scarring was anterior and circumferential rather than radial, and mostly left-sided, whereas on inspection episiotomy and perineal scarring were right sided.
Conclusions A normal perineum on clinical examination does not exclude underlying sphincter damage. The incidence of sphincter damage increases significantly when an episiotomy scar is associated with a perineal tear. 相似文献
44.
血清TPS浓度在消化道肿瘤中价值的研究 总被引:4,自引:0,他引:4
共选择30例消化道肿瘤病人,其中食管癌,胃癌,大肠癌各10例,设健康献血者30例,对两组血清特异型组织多肽抗原浓度进行了检测,结果肿瘤组血清TPS浓度明显高于健康人。消化道肿瘤阳性检出经达70%,其中食管癌80%,胃癌60%,大肠癌70%。消化道肿瘤合并淋巴转移阳性检出率达76.9%,其中食管癌100%,胃癌66.7%,大肠癌70.0%。随着病程发展,血清TPS浓度呈现升高趋势。 相似文献
45.
Terry Kwong MB BS FRACP Senior Fellow Elsa Valderrama MD Assistant Professor of Pediatric Pathology Carole Paley MD Assistant Professor of Pediatrics Norman Ilowite MD Associate Professor of Pediatrics 《Seminars in arthritis and rheumatism》1994,23(6)
Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed. 相似文献
46.
为探索天然超氧化物岐化酶(SOD)岐化超氧离子的机理,及用于临床的可能性,我们合成了乳酸、柠檬酸和酒石酸的锰(Ⅱ)配合物作为Mn-SOD的模拟物,用光照法测定了它们的活性,得到了有意义的结果:锰配合物作为Mn-SOD的模拟物,有肯定的活性,其中以乳酸锰配合物活性最高。 相似文献
47.
近年证明SRY男性性基因是性别决定关键。SRY突变能引起男性性异常。46,XY性腺发育不全(或XY女性)系SRY基因突变所致,并有高发性腺肿瘤特点。SRY突变有多种类型;本研究检测一家庭集聚性XY女性高发肿瘤成员有个SRY基因缺失。结合细胞遗传学和病理学检查结果,对XY女性性腺癌变机理提出了推测。 相似文献
48.
A study of the relationship between the delivery to cord clamping interval and the time of cord separation 总被引:1,自引:0,他引:1
A randomised controlled trial of 554 women was carried out to compare the effects of late and early umbilical cord clamping on the time of cord separation. In addition data were collected on maternal and neonatal outcomes. There were no significant differences between the two groups in the duration of cord adherence and neonatal and maternal outcomes. There appeared to be a higher rate of jaundice in the late clamped group which did not reach statistical significance. There was an unexpectedly higher rate of breast feeding at home in the late clamped group which did reach statistical significance. Overall the trial provides no clear evidence for the benefit of early cord clamping (the current policy as part of the active management of the third stage in the UK) on the outcomes considered. 相似文献
49.
FREDERIC W-B. DELEYIANNIS MD MPhil MPH DAVID B. THOMAS MD DrPH From the Departments of Otolaryngology–Head Neck Surgery Epidemiology University of Washington Seattle; the Division of Public Health Science Fred Hutchinson Cancer Research Center. 《Otolaryngology--head and neck surgery》1997,116(6):630-636
A cohort of 5180 patients with head and neck cancer, who were part of the tumor registry of the Surveillance, Epidemiology, and End Results area of western Washington State, was followed up for as many as 15 years to determine the risk of lung cancer. A sample of 522 patients from this cohort was interviewed to determine smoking history. Lung cancer developed in 356 (6.9%) of the 5180 patients. The overall annual incidence of lung cancer remained relatively constant between approximately 1.0% and 2.0% during the 15 years of follow-up. Men had an increased risk of lung cancer compared with women (relative risk [RR] = 1.56; 95% confidence interval [CI] = 1.18 to 2.03). Compared with patients with oral cavity cancer (RR = 1.00), the relative risk of lung cancer developing by the site of the index tumor was 0.63 (95% CI = 0.40 to 0.98) for lip, 1.12 (95% CI = 0.81 to 1.56) for intrinsic larynx, 1.73 (95% CI = 1.21 to 2.47) for oropharynx, 1.84 (95% CI = 1.16 to 2.92) for hypopharynx, and 2.28 (95% CI = 1.60 to 3.24) for extrinsic larynx. Among the 522 patients who were interviewed, men smoked more than women ( p < 0.0001), and patients with laryngeal or pharyngeal cancer smoked more than patients with cancer of the lip or the oral cavity ( p < 0.05). Among patients with head and neck cancer, the risk of lung cancer is highest for men and for patients with cancer of the pharynx or extrinsic larynx. These findings may be explained by differences in smoking consumption. (Otolaryngol Head Neck Surg 1997;116:630-6.) 相似文献
50.
膝关节 Q 角变化规律的实验研究 总被引:4,自引:0,他引:4
本研究利用精密三维位移测读仪,研究分析了Q角的变化趋势,以及对髌股关节运动的影响。研究结果表明,Q角是一空间夹角,随屈膝角的增大而增大。力线在平面上的投影所呈的平面夹角Qp也就是通常所指的Q角,在屈膝15°左右达最大,而在90°左右达最小。整个屈膝过程中,QP在5°-15°之间变化,变化幅度达10°左右。 相似文献