Das Atemnebengeräusch der bronchopneumonischen Maus

Zusammenfassung Bei allen in eigenen Versuchen beobachteten Bronchiopneumonien der verschiedensten Ätiologie läßt die weiße Versuchsmaus ein leises Atemgeräusch hören. Es kann durch ein tonloses ge nachgeahmt werden. Es ist mit dem vonNelson beschriebenen fälschlicherweise mit Zwitschern übersetzten Laut der Mäuse, die am Mäusekatarrh erkrankt sind, identisch.     

Zur Frage der Kreislauf- und Atmungsregulation bei exogener Hyperthermie

Zusammenfassung An Hunden in Urethan-Morphinnarkose, die durch heiße Bäder überhitzt wurden (Rectaltemp. von 38–40°), kommt es. trotz hochgradigen Absinkens der alveolaren CO₂-Spannung nicht zu einem Blutdruckabfall, sondern meist sogar zu einem Blutdruckanstieg.Es wird durch Prüfungen der Erregbarkeit der medullären Zentren gezeigt, daß diese zentrale Tonussteigerung nicht auf einer verstärkten Erregbarkeit des Kreislaufzentrums gegenüber CO₂ beruhen kann.Auch die Atemvolumensteigerung beim Hecheln beruht nicht auf einer Empfindlichkeitssteigerung des Atemzentrums gegenüber Kohlensäure.     

Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews

Conclusions based on systematic reviews of randomized controlled trials are considered to provide the highest level of evidence about the effectiveness of an intervention. This overview summarizes the available evidence from systematic reviews on the effects of nonpharmacological and nonsurgical interventions for rheumatoid arthritis (RA). Systematic reviews of studies of patients with RA (aged >18 years) published between 2000 and 2007 were identified by comprehensive literature searches. Methodological quality was independently assessed by 2 authors, and the quality of evidence was summarized by explicit methods. Pain, function, and patient global assessment were considered primary outcomes of interest. Twenty-eight systematic reviews were included in this overview. High-quality evidence was found for beneficial effects of joint protection and patient education, moderate-quality evidence was found for beneficial effects of herbal therapy (gamma-linolenic acid) and low-level laser therapy, and low-quality evidence was found for the effectiveness of the other interventions. The quality of evidence for the effectiveness of most nonpharmacological and nonsurgical interventions in RA is moderate to low.     

Use of middle hepatic vein in right lobe living donor liver transplantation

The harvesting of the middle hepatic vein (MHV) with the right lobe graft for living‐donor liver transplantation allows an optimal venous drainage for the recipient; however, it is an extensive operation for the donor. This is a prospective, nonrandomized study evaluating liver functions and early clinical outcome in donors undergoing right hepatectomy with or without MHV harvesting. From August 2005 to July 2007, a total of 100 donor right hepatectomies were performed with (n = 49) or without (n = 51) the inclusion of the MHV. The decision to take MHV was based on an algorithm that considers various donor and recipient factors. There was no donor mortality in donors in either group. Overall complication rate was higher in MHV (+) donor group, however when remnant liver volume was kept above 30%, complication rates were similar between the groups. The results of this study show that right hepatectomy including the MHV neither affects morbidity nor impairs early liver function in donors when remnant volume is kept above 30%. The decision, therefore, of the extent of right lobe donor hepatectomy should be tailored to the particular conditions considering the graft quality and metabolic demand of the recipient.     

Dual left lobe living donor liver transplantation using donors unacceptable for right lobe donation: a case report

Living donor liver transplantation (LDLT) has become a viable alternative for end-stage liver disease. The shortage of brain-dead donors has led to development of advanced surgical approaches. Dual lobe LDLT has been performed successfully in the recent years. The major indication for this complex procedure has been insufficient graft size from a single donor or insufficient remnant in the donor. We performed a dual left lobe LDLT using 2 donors who were unacceptable for right lobe donation.