Quantitative evaluation of longitudinal strain in layer-specific myocardium in patients with preeclampsia

Preeclampsia (PE) remains a main cause of maternal morbidity and mortality during pregnancy. Vascular spasm and ischemic damage play the primary role in the presentation of PE. The aim of this study was to assess the longitudinal strain (LS) in each of the three myocardial layers in patients with PE using the layer-specific strain. Forty-five PE women and forty-one normotensive pregnant women were included. Layer-specific LS were assessed in endocardium, mid-myocardium, and epicardium by 2-dimensional (2D) speckle-tracking echocardiography (STE). Compared to the control subjects, the LS of all the three analyzed myocardial layers showed a significant decline in PE patients and the greatest decrease of LS occurred in the endocardium. Considering a layer-specific analysis of myocardial deformation, there is a continuous reduced tendency from endocardial to midmyocardial and epicardial layers in PE cases. The epicardial-to-epicardial LS gradient was lower in PE women than the normotensive subjects. There are some relationship of layer-specific strain values and the pregnant outcomes in PE women. All three myocardial layers were impaired in PE cases and the most prominent decrease in myocardial function occurred in the endocardial layer. Layer-specific analysis of myocardial function performed by novel 2D STE might increase diagnostic accuracy of myocardial performance in PE patients.     

急性胰腺炎伴肝损伤的临床分析

目的 探讨急性胰腺炎(AP)严重程度与肝功能受损指标的相关性,分析AP时肝损伤的发生概率与AP严重程度之间的关系,并探讨不同严重程度的AP患者之间年龄、性别、体重指数是否存在差异.方法 通过收集2011年10月至2012年6月长沙医学院附属医院检验科的AP患者72例的临床资料,其中轻度26例、中度31例、重度15例;水肿型52例,坏死型20例.并随机选取25例健康成年人作为对照组.比较轻、中、重度3组与对照组之间年龄、性别、体质量指数的差异和肝功能受损指标ALT或AST的关系以及水肿型、坏死型AP与ALT或AST的关系并进行统计学分析.结果 对照组、轻型组、中型组和重型组之间年龄和性别比较差异无统计学意义(P>0.05),但轻型、中型、重型3组体质量指数与对照组相比差异有统计学意义(P<0.05).轻、中、重度3组病例ALT或AST阳性率与健康对照组比较差异均有统计学意义(P<0.05),而在轻、中、重度3组病例ALT或AST阳性率的两两比较中,轻度、中度和重度之间比较差异均有统计学意义(P=0.003,P=0.005),而中度与轻度之间差异无统计学意义(P>0.05).水肿型与坏死型两组ALT或AST阳性率均高于健康对照组,差异有统计学意义(P<0.05),且水肿型与坏死型两组之间ALT或AST阳性率比较,差异有统计学意义(P=0.000 1).结论 肥胖是AP的诱发因素;AP严重程度与胰腺炎伴有肝损害有一定相关性,其损害程度可反映AP严重程度;急性坏死型胰腺炎的肝损害发生率要高于水肿型胰腺炎.     

原发性肝癌晚期疼痛的评估及护理

介绍了原发性肝癌晚期病人疼痛的主要评估方法,并探讨针对各类病人应采取的相应护理对策,从而使护理人员实施有效的止痛措施及完善的护理,以减轻病人痛苦,提高其生活质量。     

New insights into the beneficial roles of dispersants in reducing negative influence of Mg2+ on molybdenite flotation

Due to the shortage of freshwater, seawater has been widely considered for mineral flotation. However, the presence of Mg²⁺ in seawater plays an apparently negative role. In this work, two dispersants (i.e., sodium silicate (SS) and sodium hexametaphosphate (SH)) were applied to reduce the detrimental effects of Mg²⁺ on the flotation of molybdenite (MoS₂). Various measurements including contact angle, zeta potential, FTIR and XPS were carried out to understand the impacts of these two dispersants on MoS₂ flotation. Results indicate that both dispersants prevented the adsorption of colloidal Mg(OH)₂ onto MoS₂ surface under alkaline conditions, thereby improving MoS₂ floatability. In addition, both dispersants are physically adsorbed on MoS₂ surface, but chemically adsorbed on Mg(OH)₂ surface. In addition, the extended Derjaguin–Landau–Verwey–Overbeek (DLVO) calculation suggests that both SS and SH reverse the total interaction energies between MoS₂ and colloidal Mg(OH)₂ from negative (attraction force) to positive (repulsive force), with the impact of SH being more significant.

Due to the shortage of freshwater, seawater has been widely considered for mineral flotation.     

链霉素缓释复合降解膜植入损伤肌腱局部腱周结缔组织的变化

背景:国内外学者曾用生物、非生物及药物等方法,诸如生物膜、透明质酸钠、纤维素密封胶等材料进行大量肌腱修复防粘连研究,但到目前为止尚未取得突破性进展。目的:观察肌腱损伤局部植入链霉素复合降解膜后腱周结缔组织的增生。方法:切断SD大鼠跟腱后,随机数字表法分为3组,分别在肌腱断端缝合处植入链霉素复合缓释降解膜、维生素C复合缓释降解膜、空白缓释降解膜。术后90d行肌腱损伤局部组织学观察、羟脯氨酸含量和生物力学指标检测。结果与结论:链霉素复合缓释降解膜组肌腱缝合处内部的成纤维细胞、胶原纤维均较其腱周围、维生素C复合缓释降解膜组、空白缓释降解膜组多;腱缝合处肌腱周围多为正常结构的疏松结缔组织,很少有增生的结缔组织长入肌腱内部;肌腱与周围组织分界清晰,最大抗拉强度、羟脯氨酸含量明显优于其他两组。表明链霉素复合缓释降解膜通过抑制腱周结缔组织增生,防止腱周结缔组织增生长入腱内,从而减轻或防止粘连形成。