全文获取类型
收费全文 | 625篇 |
免费 | 21篇 |
国内免费 | 78篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 33篇 |
妇产科学 | 8篇 |
基础医学 | 60篇 |
口腔科学 | 9篇 |
临床医学 | 144篇 |
内科学 | 99篇 |
皮肤病学 | 17篇 |
神经病学 | 79篇 |
特种医学 | 97篇 |
外科学 | 36篇 |
综合类 | 25篇 |
预防医学 | 20篇 |
眼科学 | 7篇 |
药学 | 60篇 |
1篇 | |
中国医学 | 1篇 |
肿瘤学 | 23篇 |
出版年
2021年 | 9篇 |
2019年 | 6篇 |
2017年 | 4篇 |
2016年 | 8篇 |
2015年 | 16篇 |
2014年 | 13篇 |
2013年 | 19篇 |
2012年 | 8篇 |
2011年 | 18篇 |
2010年 | 11篇 |
2009年 | 14篇 |
2008年 | 8篇 |
2007年 | 68篇 |
2006年 | 19篇 |
2005年 | 22篇 |
2004年 | 9篇 |
2003年 | 7篇 |
2002年 | 6篇 |
2001年 | 13篇 |
2000年 | 17篇 |
1999年 | 11篇 |
1998年 | 25篇 |
1997年 | 31篇 |
1996年 | 27篇 |
1995年 | 22篇 |
1994年 | 20篇 |
1993年 | 16篇 |
1992年 | 14篇 |
1991年 | 13篇 |
1990年 | 15篇 |
1989年 | 18篇 |
1988年 | 22篇 |
1987年 | 18篇 |
1986年 | 16篇 |
1985年 | 18篇 |
1984年 | 6篇 |
1983年 | 7篇 |
1982年 | 18篇 |
1981年 | 14篇 |
1980年 | 12篇 |
1979年 | 8篇 |
1978年 | 12篇 |
1977年 | 13篇 |
1976年 | 8篇 |
1975年 | 10篇 |
1974年 | 4篇 |
1972年 | 3篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 4篇 |
排序方式: 共有724条查询结果,搜索用时 453 毫秒
41.
HL Hulliduy 《Acta paediatrica (Oslo, Norway : 1992)》1993,82(S385):1028-1028
42.
The international collaborative study of maternal phenylketonuria: status report 1994 总被引:1,自引:0,他引:1
R Koch HL Levy R Matalon B Rouse WB Hanley F Trefz C Azen EG Friedan F de la Cruz F Güttler PB Acosta 《Acta paediatrica (Oslo, Norway : 1992)》1994,83(S407):111-119
Neonatal screening for phenylketonuria (PKU) has created a problem as females with PKU are reaching child-bearing age. Surveys have revealed that maternal phenylalanine blood concentrations greater than 1200 μmol/l are associated with fetal microcephaly, congenital heart defects and intrauterine growth retardation. It is estimated that as many as 3000 hyperphenylalaninemic females may be at risk of producing these fetal abnormalities. To examine this problem, the international maternal PKU collaborative study was developed to evaluate the efficacy of a phenylalanine-restricted diet in reducing fetal morbidity. Preliminary findings have indicated that phenylalanine restriction should begin before conception for females with PKU planning a pregnancy. Dietary control should maintain maternal blood phenylalanine levels between 120 and 360 μmol/l and should provide adequate energy, protein, vitamin and mineral intake. Pregnant hyperphenylalaninemic females who achieved metabolic control after conception or by the 10th week of pregnancy had a better offspring outcome than anticipated. The results of 402 pregnancies are reviewed. 相似文献
43.
Hemodilution can obviate the need for allogeneic transfusion in some patients. However, it is only one component of a comprehensive blood conservation program and should be combined with other techniques whenever possible. While most often employed in teenagers and healthy young adults, ANH has been used in small children, the elderly, and patients of all ages who are undergoing cardiac surgery. Extreme caution should be exercised if ANH is used in patients with coronary artery disease or aortic stenosis who are undergoing noncardiac surgery, because their normal compensatory mechanisms are impaired. What usually is a safe and relatively simple procedure can become a disaster if employed in inappropriately selected patients. Careful hemodynamic monitoring and maintenance of normovolemia are critical. 相似文献
44.
45.
LASZLO HEGEDÜS ANDERS DEJGAARD NIELS J. CHRISTENSEN CLAUS KÜHL 《Journal of internal medicine》1985,218(5):511-517
ABSTRACT. We examined whether the abnormal regulation of the cardiovascular system and plasma noradrenaline observed after oral glucose in insulin-dependent diabetic patients could be normalized by intravenous infusion of insulin. Eight patients with type 1 (insulin-dependent) diabetes were examined after an oral glucose load with and without simultaneous infusion of insulin. Insulin infusion increased plasma insulin from 0.07 to 0.31 nmol/1. In the control experiment (glucose only), mean heart rate and mean arterial systolic blood pressure remained unchanged and plasma noradrenaline (NA) decreased (p < 0.05). After oral glucose plus intravenous insulin, mean heart rate increased by 11 % and mean systolic blood pressure by 5 % (p < 0.05, p < 0.01), whereas plasma NA did not change significantly. The present study indicates that physiologic increments in plasma insulin concentration are of importance in the regulation of the cardiovascular system and plasma NA following an oral glucose load. 相似文献
46.
47.
48.
49.
50.
The microiontophoretic application of taurine and GABA was studied in the cerebellar cortex of the rat. Both taurine and GABA produced a dose-dependent depression of spike frequency of cerebellar neurons. GABA (2-42 nA, mean 27 nA) induced an inhibition of spike discharge on all 138 cells tested, including 29 Purkinje cells. Taurine (60-200 nA, mean 108 nA) induced an inhibition of spike discharge on 93 of the 106 cerebellar neurons tested, including inhibition on 22 of 25 Purkinje cells. Iontophoretic application of bicuculline and picrotoxin antagonized the inhibitory effects of both GABA and taurine on Purkinje cells as well as on cerebellar neurons in general. Strychnine did not antagonize the inhibition of either GABA or taurine. Simultaneous application of taurine and GABA produced a synergistic inhibitory effect on the firing rate of Purkinje cells. Taurine, in contrast to GABA, appeared to be more depressant when applied in the Purkinje cell dendritic zone than when applied near the soma. The data are discussed in terms of taurine functioning as a neurotransmitter in the cerebellum of the rat and having receptor sites distinct from those for GABA. 相似文献