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951.
952.
Current incidence and residual risk of hepatitis B infection among blood donors in the United States
Shimian Zou Susan L. Stramer Edward P. Notari Mary C Kuhns David Krysztof Fatemeh Musavi Chyang T. Fang Roger Y. Dodd 《Transfusion》2009,49(8):1609-1620
BACKGROUND: This study used two approaches to estimate the current incidence of hepatitis B virus (HBV) in a US donor population.
METHODS: HBV incidence was estimated through the hepatitis B surface antigen (HBsAg) yield approach and the seroconversion method. Residual risk was estimated by the incidence–window period model. HBsAg yield refers to an HBsAg confirmed-positive, antibody against hepatitis B core antigen (anti-HBc)–nonreactive donation, adjusted for false-positive neutralization results. The number of HBsAg-seroconverting repeat donors divided by total number of person-years of evaluation or the HBsAg yield rate divided by HBsAg yield window gave rise to incidence estimates.
RESULTS: The seroconversion and the yield approach, respectively, gave an incidence estimate of 3.41 or 3.43 per 105 person-years. Using a revised infectious window period of 38 or 30 days for current HBsAg assays, the current residual risk for HBV was respectively estimated for 2006 to 2008 at 1 in 282,000 or 1 in 357,000 donations from the seroconversion approach and 1 in 280,000 or 1 in 355,000 donations from the yield approach. With the same database and methods, this is a decrease from 1 in 86,000 to 1 in 110,000 observed in 1997 to 1999.
CONCLUSIONS: Current HBV incidence and residual risk are lower than earlier estimates, especially in the youngest donors, but remain higher in the absence of HBV nucleic acid test than those for human immunodeficiency virus or hepatitis C virus (HCV). In addition to the exclusion of HBsAg false-positive donors, the reduction could reflect shortened window periods and decreased incidence rates due to vaccination or other reasons. 相似文献
METHODS: HBV incidence was estimated through the hepatitis B surface antigen (HBsAg) yield approach and the seroconversion method. Residual risk was estimated by the incidence–window period model. HBsAg yield refers to an HBsAg confirmed-positive, antibody against hepatitis B core antigen (anti-HBc)–nonreactive donation, adjusted for false-positive neutralization results. The number of HBsAg-seroconverting repeat donors divided by total number of person-years of evaluation or the HBsAg yield rate divided by HBsAg yield window gave rise to incidence estimates.
RESULTS: The seroconversion and the yield approach, respectively, gave an incidence estimate of 3.41 or 3.43 per 10
CONCLUSIONS: Current HBV incidence and residual risk are lower than earlier estimates, especially in the youngest donors, but remain higher in the absence of HBV nucleic acid test than those for human immunodeficiency virus or hepatitis C virus (HCV). In addition to the exclusion of HBsAg false-positive donors, the reduction could reflect shortened window periods and decreased incidence rates due to vaccination or other reasons. 相似文献
953.
Fereshteh Aein ms cn phd Fatemeh Alhani ms cn phd Eesa Mohammadi ms cn phd Anoshirvan Kazemnejad ms c phd 《Nursing & health sciences》2009,11(3):221-227
The purpose of this study was to explore parents' and nurses' experiences of parental participation in child care in hospitals in Iran. Using thematic analysis, the data were collected through interviewing 14 parents and 11 nurses from two pediatric hospitals. The results showed that four major themes emerged, including the necessity of a parent's presence, the unplanned and informal delegation of care to the parents (which itself had five subthemes: the parents as nurses, the delegation of care without sufficient and planned parental training, informal parent-to-parent support, the continuum of parents' willingness to participate, and the neglect of parents' needs), the inconsistency of care, and the parents as informal evaluators of care. Based on the study's findings, effective communication by nurses with parents is required. Nurses need to make an ongoing assessment of parents' wishes for involvement and negotiate care accordingly, with enough support and supervision to warrant quality of care. 相似文献
954.
Mohammadali Nikoo Ehsan Moazen‐Zadeh Nooshin Nikoo Sanam Javidanbardan Alireza Kazemi Fiona Choi Marc Vogel Ali Gholami Saeed Tavakoli Reza Givaki Majid Jazani Fatemeh Mohammadian Nader Markazi Moghaddam Nasser Goudarzi Christian Schutz Kerry Jang Shahin Akhondzadeh Michael Krausz 《International journal of methods in psychiatric research》2019,28(1)
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Nitz Ulrike Gluz Oleg Christgen Matthias Kates Ronald E. Clemens Michael Malter Wolfram Nuding Benno Aktas Bahriye Kuemmel Sherko Reimer Toralf Stefek Andrea Lorenz-Salehi Fatemeh Krabisch Petra Just Marianne Augustin Doris Liedtke Cornelia Chao Calvin Shak Steven Wuerstlein Rachel Kreipe Hans H. Harbeck Nadia 《Breast cancer research and treatment》2019,175(1):265-266
Breast Cancer Research and Treatment - The article Reducing chemotherapy use in clinically high-risk, genomically low-risk pN0 and pN1 early breast cancer patients: five-year data from the... 相似文献
958.
Reza Rostami Reza Kazemi Michael A. Nitsche Fatemeh Gholipour 《Clinical neurophysiology》2017,128(10):1961-1970
Objective
Previous studies investigated predictors of repetitive transcranial magnetic stimulation (rTMS) response in depressive disorders but there is still limited knowledge about clinical predictors. Moreover, predictors of rTMS response in bipolar depression (BDD) are less studied than unipolar depression (UDD).Methods
We performed a binary logistic regression analysis in 248 patients with depressive disorders (unipolar N = 102, bipolar N = 146) who received 20 sessions of DLPFC rTMS (High-frequency rTMS, low-frequency rTMS, bilateral rTMS) to investigate significant clinical and demographic predictors of rTMS response. We also investigated effects of depression type, response (yes, no) and time on reducing somatic and cognitive-affective symptoms of patients.Results
Depression type (unipolar vs. bipolar) did not have a significant effect on rTMS response. 45% of all patients, 51.5% of UDD patients and 41% of BDD patients, responded to rTMS treatment. Age was the only significant demographic predictor of treatment response in all patients. Cognitive-affective symptoms, compared to somatic symptoms were significant predictors for treatment response to rTMS. Common and unique clinical predictor for UDD and BDD were identified.Conclusions
Younger patients and those with cognitive-affective rather than somatic symptoms benefit more from DLPFC rTMS treatment. rTMS is effective in UDD and BDD patients. Patients should be selected based on clinical and demographic profile.Significance
Findings are based on the largest thus far reported sample of patients with depressive disorders that received DLPFC rTMS. 相似文献959.
Association between 318C/T polymorphism of the CTLA‐4 gene and systemic lupus erythematosus in Iranian patients 下载免费PDF全文
960.
Sanaz Shanbehzadeh Mohammad Ali Mohseni Bandpei Fatemeh Ehsani 《Knee surgery, sports traumatology, arthroscopy》2017,25(5):1432-1442