Second Twin: Quality of Survival if Born by Breech Extraction Following Internal Podalic Version

The intrapartum management of the vertex-breech and vertex-transverse twin gestation is controversial. The fall in perinatal mortality rate to a low level has resulted in this parameter failing to be an adequate gauge of the safety of breech extraction and the answer lies in the quality of survival of the infants. Fifty-one twin pairs, collected over 12 years at the Mercy Hospital for Women, Melbourne, occurred where twin 2 was born by breech extraction following internal inversion and the control (twin 1) did not have this procedure performed. In 8 pairs either a stillbirth or neonatal death occurred; in one pair childhood death due to an accident (fire) occurred; in 4 pairs the parents refused entrance to the study as they perceived both twins to be similar; in 2 sets the assessment was incomplete; 11 sets were untraceable leaving 25 sets fully assessed as children ranging in age from 2 to 12 years. Growth, and psychological scores were not significantly different between twins 1 and 2 but 2 children had cerebral palsy and both were born by breech extraction following internal version at 29.2 and 30.1 weeks' gestation, respectively. Because of small numbers the results failed to achieve statistical significance and this study was unable to answer the question regarding the safety of breech extraction following internal version but did show that the majority of infants so born do well.     

Oxytocin Titration for Induction of Labour: A Prospective Randomized Study of 15 Versus 30 Minute Dose Increment Schedules

Two hundred and twenty four patients admitted for induction of labour were randomized into 2 groups. The oxytocin dose was escalated every 15 minutes in the first group whilst for the second group the dose was increased every 30 minutes till optimal uterine activity was achieved. There was no significant difference in the mean maximum dose of oxytocin and length of labour in the 2 groups studied. Transient reduction of the dose of oxytocin was needed in 20.5% of patients in the '15 minute' group and 17.0% of cases in the '30 minute' group because of uterine hyperstimulation or fetal heart rate (FHR) changes; this difference was not statistically significant. The incidence of operative deliveries were similar in the 2 groups. The neonatal 1 and 5 minute Apgar scores, cord arterial blood pH, incidence of assisted ventilation and admission to the neonatal intensive care unit were similar in the 2 groups. The 15 minute schedule does not offer any advantage over the 30 minute escalation schedule for induction of labour. Hyperstimulation and FHR changes are a possibility with any regimen and close monitoring of FHR and uterine activity is advisable with the use of oxytocin.     

Management of Infective Endocarditis in Pregnancy

EDITORIAL COMMENT: : We accepted this paper for publication to remind readers that bacterial endocarditis can occur in pregnancy and requires prompt diagnosis and treatment for favourable results. Fever and/or urinary symptoms should suggest the diagnosis especially when the women is known to have a cardiac murmur. We were interested to read how echocardiography can reveal the presence of vegetations on affected valves. Our cardiologist reviewer was not 100% convinced that the diagnosis was proven in Case 1 since 'many patients would have bacteraemic episodes with a known cardiac lesion which does not necessarily go on to produce endocarditis'. Our reviewer considered the diagnosis in Case 2 to be clear-cut, but was surprised how successful antibiotic therapy alone was in view of the evidence of peripheral embolization.     

Pelvic Lymph Node Metastases in Early Invasive Carcinoma of the Cervix - Histopathological ''Risk'' Factors

Histopathological features in 89 cases of Stage 1B and early 2A invasive carcinoma of the cervix who underwent Wertheim radical hysterectomy and pelvic lymphadenectomy were studied. Depth of tumour invasion and lymphatic/vascular space permeation by tumour cells were significantly associated with lymph node metastases. The other features such as tumour type, and stromal leucocytic reaction showed no significant relationship to the presence of lymph node metastases.     

Presacral Neurectomy - A Reappraisal

Between April 1984 and April 1990, 20 patients with a mean age of 27.9 years underwent presacral neurectomy at The Royal Women's Hospital, Melbourne, Australia. Overall, 11 of the 19 patients (58%) assessable for follow-up were totally cured of pain and 8 (42%) were partially cured. The most common indication for presacral neurectomy was secondary dysmenorrhoea, usually in association with endometriosis or pelvic adhesions. In 4 patients with uterine dysmenorrhoea not associated with pelvic pathology the operation produced a complete cure. The general consensus of gynaecological opinion is that presacral neurectomy should still be reserved for a limited number of carefully selected patients in whom other methods of treatment have been exhausted. It is imperative that a prior psychological assessment should be undertaken whenever a functional component is suspected. Whilst pain of uterine origin may be cured by presacral neurectomy, lateral pelvic pain of adnexal origin requires ovarian sympathectomy.     

Advanced Extrauterine Pregnancy Mimicking Intra-Uterine Fetal Death: Case Reports

Two cases of late second trimester extrauterine pregnancy are presented--intraabdominal pregnancy in one and an ampullary pregnancy in another. In the former the diagnosis was made only after attempts at induction of labour for fetal death with prostaglandins failed and in the latter only at laparotomy. The diagnostic and surgical problems encountered are discussed.     

Simple Office Methods to Predict Ovulation: The Clinical Usefulness of a New Urine Luteinizing Hormone Kit Compared to Basal Body Temperature, Cervical Mucus and Ultrasound

A new urine luteinizing hormone (LH) kit, First Response (Tambrands Inc., Palmer, MA) was compared with basal body temperature (BBT), cervical mucus scoring and abdominal ultrasound follicular scanning in their ability to predict ovulation to within 2 days of the serum LH peak. BBT was kept daily. From day 10 daily ultrasound scanning and cervical mucus examination were performed and serum oestradiol, luteinizing hormone, follicular stimulating hormone and progesterone were assayed. First Response was significantly more accurate than BBT and cervical mucus when compared in their ability to predict ovulation to within 2 days of the LH peak (p less than 0.05). First Response pinpointed 93% (27/29) of the ovulatory cycles compared to 72% (18/25) and 61% (19/31) for BBT and cervical mucus respectively. It was better but not significantly so against abdominal ultrasound which predicted 77% (24/31). The implications of this finding and the value of the other simple office tests in clinical practice are discussed.     

Secondary Postpartum Haemorrhage

Eighty-three cases of secondary postpartum haemorrhage managed in this teaching unit over a 3-year period are described. Bleeding occurred most frequently between the 8th and 14th day of the puerperium; 73% of the patients had already been discharged from hospital and required readmission. Suction evacuation was performed in 72 patients and was successful in arresting haemorrhage whether retained placental tissue could be demonstrated on histology or not. There was histological confirmation of retained gestational products in only 30 (42%) of the patients treated surgically. No predictive factors for secondary postpartum haemorrhage could be identified in the obstetric profiles or antenatal course of most of these patients. Patients with retained gestational products could not be distinguished from those without on the basis of history or examination alone apart from 4 patients noted to have incomplete membranes at delivery.     

Cervical Cancer in South Australia: Trends in Incidence, Mortality and Case Survival

Summary: Approximately 90% of cervical cancers are considered preventable through regular screening and the treatment of precursor lesions, but fewer than 20% of South Australian women were found to have been screened in 1984.
Data from the State Cancer Registry have shown an increase in cervical cancer incidence of approximately 80% in women under 50 years of age in the 9-year period to 1986, but a decrease of about 25% in older women. Mortality data have shown similar patterns by age, although the increase in younger women tended to extend to an older age.
Case survival was unchanged between the diagnostic periods 1977–1981 and 1982–1987 and there was little change in the proportion of cases that were adeno-carcinomas.