全文获取类型
收费全文 | 250524篇 |
免费 | 39693篇 |
国内免费 | 2733篇 |
专业分类
耳鼻咽喉 | 6231篇 |
儿科学 | 7935篇 |
妇产科学 | 4043篇 |
基础医学 | 17918篇 |
口腔科学 | 3637篇 |
临床医学 | 36969篇 |
内科学 | 68184篇 |
皮肤病学 | 9170篇 |
神经病学 | 25398篇 |
特种医学 | 10430篇 |
外国民族医学 | 6篇 |
外科学 | 55038篇 |
综合类 | 1485篇 |
现状与发展 | 72篇 |
一般理论 | 74篇 |
预防医学 | 15027篇 |
眼科学 | 5048篇 |
药学 | 7926篇 |
中国医学 | 126篇 |
肿瘤学 | 18233篇 |
出版年
2023年 | 5208篇 |
2022年 | 2109篇 |
2021年 | 5225篇 |
2020年 | 7259篇 |
2019年 | 4144篇 |
2018年 | 9677篇 |
2017年 | 8989篇 |
2016年 | 10387篇 |
2015年 | 10744篇 |
2014年 | 18578篇 |
2013年 | 19756篇 |
2012年 | 12133篇 |
2011年 | 12216篇 |
2010年 | 14182篇 |
2009年 | 17693篇 |
2008年 | 11717篇 |
2007年 | 10493篇 |
2006年 | 12438篇 |
2005年 | 9710篇 |
2004年 | 8605篇 |
2003年 | 6979篇 |
2002年 | 7068篇 |
2001年 | 5592篇 |
2000年 | 4727篇 |
1999年 | 4797篇 |
1998年 | 4830篇 |
1997年 | 4422篇 |
1996年 | 4129篇 |
1995年 | 3983篇 |
1994年 | 2620篇 |
1993年 | 2183篇 |
1992年 | 2509篇 |
1991年 | 2450篇 |
1990年 | 2057篇 |
1989年 | 2129篇 |
1988年 | 1864篇 |
1987年 | 1649篇 |
1986年 | 1707篇 |
1985年 | 1531篇 |
1984年 | 1219篇 |
1983年 | 1090篇 |
1982年 | 1060篇 |
1981年 | 849篇 |
1980年 | 751篇 |
1979年 | 817篇 |
1978年 | 724篇 |
1977年 | 758篇 |
1975年 | 603篇 |
1974年 | 574篇 |
1972年 | 605篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
131.
Zaher H. Sbeity Axel Jaksche Sybille Martin Karin U. Loeffler 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2006,244(7):883-884
Purpose We report a case of periocular subcutaneous macrofilariasis as an initial sign of a systemic Loa loa infection.Methods Thorough history, eye examination and surgical intervention. Parasitological and serological analysis.Results A periocular adult Loa loa worm was extracted from the left upper eyelid in an African student living in Germany after presenting to our department with intermittent attacks of painful lid swelling. Four weeks later he presented with Calabar swellings in his arms without serological evidence of microfilaria and was treated with diethylcarbamazine.Conclusion Due to increasing migration of populations to Europe rare manifestations of ocular loiasis are becoming more common. Intermittent painful eyelid swelling in patients who visited or have lived in Africa should always raise the suspicion of systemic loiasis. 相似文献
132.
Postoperative nomogram for disease-specific survival after an R0 resection for gastric carcinoma. 总被引:8,自引:0,他引:8
Michael W Kattan Martin S Karpeh Madhu Mazumdar Murray F Brennan 《Journal of clinical oncology》2003,21(19):3647-3650
PURPOSE: Few published studies have addressed individual patient risk after R0 resection for gastric cancer. We developed and internally validated a nomogram that combines these factors to predict the probability of 5-year gastric cancer-specific survival on the basis of 1,039 patients treated at a single institution. METHODS: Nomogram predictor variables included age, sex, primary site (distal one-third, middle one-third, gastroesophageal junction, and proximal one-third), Lauren histotype (diffuse, intestinal, mixed), number of positive lymph nodes resected, number of negative lymph nodes resected, and depth of invasion. Death as a result of gastric cancer was the predicted end point. The concordance index was used as an accuracy measure, with bootstrapping to correct for optimistic bias. Calibration plots were constructed. RESULTS: Gastric cancer-specific survival at 5 years was 50%. A nomogram was constructed on the basis of a Cox regression model. The bootstrap-corrected concordance index was 0.80. When compared with the predictive ability of American Joint Committee on Cancer stage, the nomogram discrimination was superior (P <.001). Nomogram calibration appeared to be excellent. CONCLUSION: A nomogram was developed to predict 5-year disease-specific survival after R0 resection for gastric cancer. This tool should be useful for patient counseling, follow-up scheduling, and clinical trial eligibility determination. 相似文献
133.
134.
135.
Bo Jørgensen MD ; Gitte Juel Friis PhD ; Finn Gottrup MD DMSci 《Wound repair and regeneration》2006,14(3):233-239
Wound pain is a serious problem for elderly patients suffering from chronic leg ulcers, and it may lead to reduced wound healing rates and reduced quality of life. Biatain-Ibu Non-adhesive (Coloplast A/S), a new pain-reducing moist wound healing dressing containing ibuprofen was tested for pain reduction, safety, and efficacy on 10+2 patients in a single-blinded crossover study against Biatain Non-adhesive (Coloplast A/S). Pain was measured with a Numeric Box Scale before, during, and after dressing change. Quality of life was measured using the World Health Organization-5 Well-Being Index. Dressing moist wound healing properties such as absorption capacity and leakage were tested together with assessment of wound exudate and blood plasma content of ibuprofen. Use of the Biatain-Ibu foam dressing correlated with a decrease in pain intensity scores from 7 in the run-in period to approximately 2.5 in the Biatain-Ibu treatment phase. Quality of life measures were improved which together with the reduced pain could contribute to faster wound healing. The moist wound healing properties of Biatain-Ibu were similar to that of the Biatain Non-adhesive and ulcer size was reduced by 24% during the treatment period. Neither side effects nor systemic plasma concentrations of ibuprofen were observed. These data indicate that Biatain-Ibu could reduce persistent and temporary wound pain, increase Quality of life, was found safe to use, and had excellent moist wound healing properties. 相似文献
136.
137.
138.
139.
José Luis R Martin Víctor Pérez Montse Sacristán Fernando Rodríguez-Artalejo Cristóbal Martínez Enric Alvarez 《European psychiatry》2006,21(1):11-20
OBJECTIVE: To assess antipsychotic medication in the treatment of schizophrenia, based on trial drop-out rates. METHOD: The studies included were randomised controlled trials that compared any of the four clinically best-established atypical antipsychotics (quetiapine, olanzapine, risperidone or clozapine) against either of two typical antipsychotics regarded as the gold standard (haloperidol or chlorpromazine). RESULTS: Meta-analysis indicated less risk of all-cause patient withdrawal from atypical medication trials where dosage was flexible, in both the short, relative risk (RR) 0.70 (95% CI 0.64-0.76), P<0.00001, and long term, RR 0.72 (0.65-0.80), P<0.00001. Similar results were observed for withdrawal due to adverse events, RR: 0.54 (0.41-0.72), P<0.0001. Nevertheless, the favourable effects of atypical medication disappeared in trials relying on fixed dosage. CONCLUSIONS: We detected a significant positive effect in terms of the outcome of treatment discontinuation for atypical versus typical medication, though only where the use of flexible rather than fixed doses (closer to an experimental control situation) was possible. 相似文献
140.