全文获取类型
收费全文 | 709篇 |
免费 | 49篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 43篇 |
妇产科学 | 11篇 |
基础医学 | 105篇 |
口腔科学 | 12篇 |
临床医学 | 67篇 |
内科学 | 128篇 |
皮肤病学 | 17篇 |
神经病学 | 34篇 |
特种医学 | 119篇 |
外科学 | 42篇 |
综合类 | 106篇 |
预防医学 | 28篇 |
眼科学 | 4篇 |
药学 | 23篇 |
中国医学 | 1篇 |
肿瘤学 | 28篇 |
出版年
2023年 | 2篇 |
2022年 | 3篇 |
2021年 | 7篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 4篇 |
2017年 | 9篇 |
2016年 | 9篇 |
2015年 | 20篇 |
2014年 | 26篇 |
2013年 | 18篇 |
2012年 | 34篇 |
2011年 | 17篇 |
2010年 | 33篇 |
2009年 | 34篇 |
2008年 | 36篇 |
2007年 | 27篇 |
2006年 | 18篇 |
2005年 | 13篇 |
2004年 | 13篇 |
2003年 | 13篇 |
2002年 | 11篇 |
2001年 | 19篇 |
2000年 | 12篇 |
1999年 | 21篇 |
1998年 | 48篇 |
1997年 | 42篇 |
1996年 | 34篇 |
1995年 | 20篇 |
1994年 | 29篇 |
1993年 | 22篇 |
1992年 | 7篇 |
1991年 | 11篇 |
1990年 | 10篇 |
1989年 | 12篇 |
1988年 | 13篇 |
1987年 | 25篇 |
1986年 | 11篇 |
1985年 | 12篇 |
1984年 | 8篇 |
1983年 | 8篇 |
1982年 | 14篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1979年 | 3篇 |
1978年 | 8篇 |
1977年 | 4篇 |
1976年 | 8篇 |
1975年 | 5篇 |
1967年 | 1篇 |
排序方式: 共有773条查询结果,搜索用时 15 毫秒
771.
Luzia E Galdeano Rejane K Furuya Manuel A Rodrigues Rosana AS Dantas Lídia A Rossi 《Journal of clinical nursing》2014,23(11-12):1532-1540
Aims and objectives. To perform the semantic validation and to evaluate the reliability and the presence of ceiling and floor effects of the Cardiac Patients Learning Needs Inventory in Portuguese patients with coronary artery disease. Background. Information should be selected based on what patients know and need to learn, which means that the teaching process should be based on each person’s needs. The Cardiac Patients Learning Needs Inventory is aimed at identifying the cardiac patients’ individual learning needs. Design. Methodological research design. Methods. Two hundred patients hospitalised at the coronary intensive care unit or at the cardiothoracic surgery unit of a public hospital in Lisbon answered the adapted version of the Cardiac Patients Learning Needs Inventory. Internal consistency was estimated based on Cronbach’s alpha. Scores above 0·50 were considered acceptable. Stability was measured through test–retest and calculated using student’s t test. Significance was set at 0·05. Results. Patients’ mean age was 65 years (SD = 11·8), and most were men (152; 76%). Cronbach’s alpha for the total scale was high in the first and second measurement (0·91), and for seven domains, it was acceptable in the first and second measurement (range from 0·50–0·89). No statistically significant difference was found between mean scores on the first and second measurement. Lower diversity was observed in the answers, most of which ranged between important and very important (ceiling‐effect). Conclusion. The adapted version for use in Portugal maintained the conceptual, semantic and idiomatic equivalences of the original version and showed adequate reliability. Relevance to clinical practices. Owing to the lack of validated instruments translated into Portuguese, to measure cardiac patients’ learning needs, this study entails important clinical and theoretical implications. 相似文献
772.
773.
Characterization of novel akermanite:poly‐ϵ‐caprolactone scaffolds for human adipose‐derived stem cells bone tissue engineering 下载免费PDF全文
AS Zanetti GT McCandless JY Chan JM Gimble DJ Hayes 《Journal of tissue engineering and regenerative medicine》2015,9(4):389-404
In this study, three different akermanite:poly‐?‐caprolactone (PCL) composite scaffolds (wt%: 75:25, 50:50, 25:75) were characterized in terms of structure, compression strength, degradation rate and in vitro biocompatibility to human adipose‐derived stem cells (hASC). Pure ceramic scaffolds [CellCeramTM, custom‐made, 40:60 wt%; β‐tricalcium phosphate (β‐TCP):hydroxyapatite (HA); and akermanite] and PCL scaffolds served as experimental controls. Compared to ceramic scaffolds, the authors hypothesized that optimal akermanite:PCL composites would have improved compression strength and comparable biocompatibility to hASC. Electron microscopy analysis revealed that PCL‐containing scaffolds had the highest porosity but CellCeramTM had the greatest pore size. In general, compression strength in PCL‐containing scaffolds was greater than in ceramic scaffolds. PCL‐containing scaffolds were also more stable in culture than ceramic scaffolds. Nonetheless, mass losses after 21 days were observed in all scaffold types. Reduced hASC metabolic activity and increased cell detachment were observed after acute exposure to akermanite:PCL extracts (wt%: 75:25, 50:50). Among the PCL‐containing scaffolds, hASC cultured for 21 days on akermanite:PCL (wt%: 75:25) discs displayed the highest viability, increased expression of osteogenic markers (alkaline phosphatase and osteocalcin) and lowest IL‐6 expression. Together, the results indicate that akermanite:PCL composites may have appropriate mechanical and biocompatibility properties for use as bone tissue scaffolds. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献