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421.
Aspergillosis of the nose and paranasal sinuses has classically been divided into four types: allergic, non-invasive, invasive and fulminant. Recent reports have suggested that a semi-invasive form with bone destruction and erosion, but without fungal tissue invasion, may occur. We present a case of allergic non-invasive aspergillosis of the paranasal sinuses with associated bone destruction extending into the orbit and anterior cranial fossa, in a non-immunocompromised patient. Surgical debridement combined with a prolonged course of oral itraconazole has resulted in long-term resolution with no evidence of recurrence of disease five years later. 相似文献
422.
Tierney PA Price T Gillet D Oyarzabal MO Salama N 《The Journal of laryngology and otology》2001,115(2):87-90
A prospective audit of the procedure and outcome in the management of acute otitis externa was undertaken in our unit. The first cycle demonstrated a heterogeneous approach and clinical isolation of junior staff. A questionnaire survey of local general practitioners highlighted clinical confusion over the use of topical medication and a need for improved access to facilities for aural toilet. General practitioner liaison and education was an essential component in formulating a change in practice. In particular, open access for aural toilet was introduced and utilization encouraged. Following changes in practice, the second cycle of the audit showed that treatment protocols were effective and adhered to by junior staff. 相似文献
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Maria Efthymiou Ian J. Mackie Philip J. Lane Danieli Andrade Rohan Willis Doruk Erkan Savino Sciascia Steven Krillis Elisa Bison Margarete Borges Galhardo Vendramini Zurina Romay‐Penabad Miao Qi Maria Tektonidou Amaia Ugarte Cecilia Chighizola H. Michael Belmont Maria Angeles Aguirre Lanlan Ji D. Ware Branch Guilherme de Jesus Paul R. Fortin Laura Andreoli Michelle Petri Ricard Cervera Esther Rodriguez Jason S. Knight Tatsuya Atsumi Joann Vega Ecem Sevim Maria Laura Bertolaccini Vittorio Pengo Hannah Cohen 《Journal of thrombosis and haemostasis》2019,17(12):2069-2080
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Capelastegui A España PP Quintana JM Gallarreta M Gorordo I Esteban C Urrutia I Bilbao A 《The American journal of medicine》2008,121(10):845-852
Objective
This study was designed to assess 8-year trends in the duration of hospitalization for community-acquired pneumonia and to evaluate the impact of declining length of stay on postdischarge short-term readmission and mortality.Methods
We conducted a prospective observational cohort study of 1886 patients with community-acquired pneumonia who were discharged from a single hospital between March 1, 2000, and June 30, 2007. The main outcomes measured were all-cause mortality and hospital readmission during the 30-day period after discharge. Regression models were used to identify risk factors associated with hospital length of stay and the adjusted associations between length of stay and mortality and readmission.Results
Factors associated with a longer hospital stay included the number of comorbid conditions, high risk classification on the Pneumonia Severity Index, bilateral or multilobe radiographic involvement, and treatment failure. Patients treated with an appropriate antibiotic were less likely to have an increased length of stay. The mean length of stay was significantly shorter during the 2006 to 2007 period (3.6 days) than during the 2000 to 2001 period (5.6 days, P <.001). Despite the reduction in length of stay, there were no significant differences in the likelihood of death or readmission at 30 days between the 2 time periods. Adjusted multivariate analysis showed that patients with hospital stays less than 3 days did not have significant increases in postdischarge outcomes.Conclusion
The marked decreased in the length of stay for patients hospitalized with community-acquired pneumonia since 2000 has not been accompanied by an increase in short-term mortality or hospital readmission. 相似文献429.
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Sayed Obaidullah Aseem Nidhi Jalan-Sakrikar Cheng Chi Amaia Navarro-Corcuera Thiago M. De Assuncao Feda H. Hamdan Shiraj Chowdhury Jesus M. Banales Steven A. Johnsen Vijay H. Shah Robert C. Huebert 《Gastroenterology》2021,160(3):889-905.e10
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