上海市宝山区电焊工人极低频磁场暴露与心理状态现况调查

[目的]评估上海市宝山区电焊工人极低频磁场暴露水平和焦虑、抑郁状况。[方法]选取宝山区4家企业81名电焊工人,采用个体测量仪EMDEX—LITE收集8h极低频磁场暴露数据,调查个人基本信息及当天活动情况,同时发放焦虑自评量表（SAS）和抑郁自评量表（SDS）进行调查。[结果]研究对象为男性67人、女性14人,年龄19～53岁;工人8h累积暴露量中位数为15．49μT／h,四分位数间距（IQR）为23．01μT／h;35．8％的被调查工人瞬时暴露中位数高于界点（0．4μT）;工人极低频磁场平均累积暴露水平明显高于对照人群（高校学生）;所有工人（100％）暴露峰值均出现于电焊作业时;与国内常模相比,工人SDS总标准分无明显差异,SAS总标准分明显增高,但未达到轻度焦虑（抑郁）症的标准;相关分析显示SDS总分与工龄呈正相关（r=0．256,P〈0．05）。[结论]电焊作业与极低频磁场的暴露强度密切相关,尚不能认为极低频磁场暴露可增加工人焦虑或抑郁症的发生。     

重度毒鼠强中毒致神经系统损害的治疗(附11例分析)

毒鼠强是一种对人畜均有剧毒的毒物 ,其对人的半数致死量为 0 .1～ 0 .2ｍｇ/ｋｇ。因自服 ,误服 ,投毒而发生中毒。轻度中毒经常规处理 ,一般不遗留神经系统受损后遗症 ,重度中毒则有很高的病死率 ,即使抢救存活者许多都遗留有较长时间神经系统受损的表现。近期经我院神经科系     

脂肪干细胞侧脑室定向移植改善脑出血大鼠的神经功能

Objective To study improvement of neural function by stereotaxic transplantation of adipose-derived stem cells (ADSC) into lateral cerebral ventricle after intracerebral hemorrhage in rats and its mechanism. Methods ADSC were cultured and proliferated in vitro, which had been marked with Brdu for 48 h before transplantation. The rat caudate nucleus hemorrhage (ICH) models were divided into 2 groups. ADSC were stereotaxically transplanted into the right lateral ventricles in ADSC group, and equal volume of saline was transplanted into control group. The score of neurological behavior were evaluated at modeling and 1, 3, 7, 14, 28 days after transplantation respectively.Double-staining immunofluorescence technique was used to detect Brdu-positive cells and the differentiation of neurons and astrocytes. In accordance with the instructions of TUNEL kit, cell apoptosis, and the expression of VEGF and angiogenesis were assayed. Results In vitro ADSC expressed undergo osteogenic and adipogenic differentiation. Compared with the control group, ADSC group had better motor function at 3, 7, and 14 days (P＜0. 05). Double-staining immunofluorescence showed mostly grafted Brdu-reactive ADSC had migrated to the hematoma zone, and some survivedand expressed Neun of Gfap. TUNEL analysis revealed that, 3 days after transplantation, the number of apoptotic cells in ADSC group was significantly less than in the control group (P＜0. 05). Three days after transplantation, VEGF expression levels in ADSC group were significantly higher than in the control group (P＜0. 05). Conclusion ADSC stereotaxially transplanted into the lateral ventricle can survive and differentiate into neuron-like cells. ADSC transplantation may reduce apoptosis and secret VEGF to promote the angiogenesis, and improve neural functional in intracerebral hemorrhage rats.     

平山病的临床神经电生理学特点

目的:探讨平山病的临床神经电生理学特点及其可能的发病机制。方法:对45例平山病患者进行神经传导速度、F波以及针极肌电图检测。结果:神经传导速度测定总异常率为24.4%(44/180),主要表现为运动神经DML延长以及CMAP波幅减低,感觉神经传导速度均正常。F波平均最小潜伏期为(26.64±3.10)ms,平均出现率为(58.77±35.53)%,总异常率为75.6%(34/45)。针极肌电图检测中57.7%表现为神经源性损害,主要异常为出现自发电位,MUPs时限延长、波幅增宽、多相波增多,募集相异常。前臂肌肉的异常率为患侧伸指总肌(100%)≥健侧伸指总肌(100%)>患侧拇短展肌(97.8%)>患侧小指展肌(97.7%)>健侧拇短展肌(82.6%)>患侧肱二头肌(75.0%)。双侧三角肌、健侧肱二头肌、下肢胫骨前肌、胸锁乳突肌肌电图正常。结论:根据平山病临床神经电生理学表现推测平山病可能为颈段脊髓病变。     

脊髓灰质炎后综合症2例临床分析

<正>脊髓灰质炎后综合症(post-poliomyelitis syndrome,PPS)是指儿时患过急性脊髓灰质炎的患者,症状部分或全部恢复并稳定若干年后再次出现神经肌肉症状。现对2例PPS患者进行临床分析。     

微格学习方法在中医护理操作中的实践——以江西中医药大学护理学院为例

微格学习方法是一种创新性的学习方法,针对中医护理操作课程的综合性、实践性、应用性等特点,可将此种学习方法运用于中医护理操作学习中。基于此,作者团队以江西中医药大学护理学院为例,在进行微格学习方法实验研究时,结合各种学习理论及实验过程中的体验,对运用该学习方法的特点进行分析并对其应用过程中产生的问题进行了反思。     

脂肪干细胞移植修复周围神经损伤的研究进展

<正>周围神经损伤后,受该神经支配区的运动、感觉和营养均将发生障碍。临床上表现为肌肉瘫痪,皮肤萎缩,感觉减退或消失。目前周围神经损伤的修复仍是临床一大难题。近年来许多学者开始探索用胚胎干细胞、骨髓间充质干细胞等移植修复周围神经损伤[1],但都存在伦理学或取材难等问题。近年来很多科学家开始对脂肪组织来源的干细胞(adipose-derived stem cells,ADSCs)进行研究。ADSCs的分离方法由Zuk等[2]于2001年首次提     

麻果中毒性脑病1例临床分析

<正>患者,男,28岁。因"记忆力减退10月,精神异常7月,加重1月"入院。患者于10月前渐出现记忆力减退,以近事记忆减退明显,7月前出现精神行为异常,脾气怪戾,在当地医院诊断为"精神分裂