单纯碎裂电位指导心房颤动消融的初步临床观察

Objective To evaluate the feasibility of mdiofrequency catheter ablation of atrial fibrilla-tion (AF) guided by complex fractionated atrial electrograms (CFAEs). Methods Twenty-two patients with drug refractory and symptomatic AF(16 paroxysmal, 6 persisten) were enrolled. Using Carto, the left atrial or biatrial replica was created during spontaneous or induced AF, and areas associated with CFAEs were identi-fied. Radiofrequency ablation at the site with CFAEs was performed and the end points were to eliminate CFAEs or convert to sinus rhythm. Results Thirteen patients(59%)were converted to sinus rhythm, (7 cases conver-ted directly to sinus rhythm, and 6 via the intermediate atrial tachycardia(AT) or atrial flutter (AFL). The re-maining nine patients required cardioversion with D. C. shock or drug. Repeat ablation was performed in 6 pa-tients (5 AT/AFL, 1 paroxysmal AF). During(10.9 ±4.8) months follow-up, 16 patients (73%) were free of arrhythmia and symptoms. CFAEs were most commonly found along the left interatrial septum, pulmonary veins, left atrial roof. CFAEs ablation prolonged AFCL[(157 ± 18) ms vs (211 ± 32) ms, P < 0.05]. Only one patient had pericardial tamponade that required pericardiocentesis. Conclusion Radiofrequeney catheter abla-tion of atrial fibrillation (AF) guided by CFAEs is safe and effective.     

单纯碎裂电位指导心房颤动消融的初步临床观察

Objective To evaluate the feasibility of mdiofrequency catheter ablation of atrial fibrilla-tion (AF) guided by complex fractionated atrial electrograms (CFAEs). Methods Twenty-two patients with drug refractory and symptomatic AF(16 paroxysmal, 6 persisten) were enrolled. Using Carto, the left atrial or biatrial replica was created during spontaneous or induced AF, and areas associated with CFAEs were identi-fied. Radiofrequency ablation at the site with CFAEs was performed and the end points were to eliminate CFAEs or convert to sinus rhythm. Results Thirteen patients(59%)were converted to sinus rhythm, (7 cases conver-ted directly to sinus rhythm, and 6 via the intermediate atrial tachycardia(AT) or atrial flutter (AFL). The re-maining nine patients required cardioversion with D. C. shock or drug. Repeat ablation was performed in 6 pa-tients (5 AT/AFL, 1 paroxysmal AF). During(10.9 ±4.8) months follow-up, 16 patients (73%) were free of arrhythmia and symptoms. CFAEs were most commonly found along the left interatrial septum, pulmonary veins, left atrial roof. CFAEs ablation prolonged AFCL[(157 ± 18) ms vs (211 ± 32) ms, P < 0.05]. Only one patient had pericardial tamponade that required pericardiocentesis. Conclusion Radiofrequeney catheter abla-tion of atrial fibrillation (AF) guided by CFAEs is safe and effective.     

早产预测——超声指标的研究

目的:前瞻性研究超声预测早产指标的临床价值。方法:选择孕龄20～37周孕妇386例,孕期内常规行会阴超声检查,以宫颈长度及宫颈指数为检查指标,根据孕妇的分娩结局分为3组:①正常组328例;②自然早产组31例;③先兆早产组27例,研究两项指标与早产发生的关系。结果:1.正常组平均宫颈长度3.67±0.72cm,平均宫颈指数0.37±0.27;早产组平均宫颈长度2.64±0.80cm,平均宫颈指数0.82±0.55,与正常组比较有极显著差异,P<0.01;先兆早产组平均宫颈长度3.36±0.89cm,P<0.05,平均宫颈指数0.44±0.38,P>0.05,提示先兆早产以宫颈长度改变为主。2.宫颈长度与早产的发生呈负相关关系,r=-0.96,宫颈指数与早产呈正相关关系,r=0.93。结论:宫颈长度及宫颈指数可作为预测早产的可行性指标,预测早产的警界值为宫颈长度≤3.0cm,宫颈指数≥0.5,预测早产的危险值为宫颈长度≤2.5cm,宫颈指数≥0.8。     

中西医结合治疗肛门尖锐湿疣36例

目的观察中西医结合治疗肛门尖锐湿疣的临床疗效。方法采用自拟祛疣汤内服结合现代医学治疗肛门尖锐湿疣36例。结果全部临床治愈。结论中西医结合治疗肛门尖锐湿疣有显著疗效。     

联合使用宫缩素和米索前列醇预防产后出血的疗效分析

目的:探讨联合使用缩宫素和米索前列醇预防产后出血的临床疗效。方法:对2013年12月~2014年5月期间我院收治的200例产妇的临床资料进行回顾性分析。我们将这200例产妇随机分为对照组和观察组,每组各有100例产妇。为对照组产妇使用缩宫素预防产后出血,为观察组产妇联合使用缩宫素和米索前列醇预防产后出血。治疗结束后,比较两组产妇的第三产程时间、产后24h的出血量、产后的出血率及不良反应的发生率。结果:治疗结束后,观察组产妇的第三产程时间、产后24h的出血量及产后的出血率明显好于对照组产妇,二者相比差异具有显著性(P<0.05)。观察组产妇不良反应的发生率为6.0%,对照组产妇不良反应的发生率为8.0%。两组产妇不良反应的发生率相比差异不具有显著性(P>0.05)。结论:联合使用缩宫素和米索前列醇预防产后出血的临床效果好,安全性高。此治疗方法值得在临床上推广应用。     

联合用药治疗宫颈阴道炎353例分析

目的探讨联合用药治疗恶性循环 病原所致的宫颈阴道炎的疗效。方法 将３５３例混合性病原所致的病人按主要致病原（念珠菌、滴虫、淋菌、雌激素低下）的不同分为四组。每组再分为三组,第１组用环丙沙星栓加克霉唑栓、灭滴灵栓、骨注壮观霉素或用已烯雌酚栓治疗;第２组联合用药但不用环丙沙星栓;第３组只用环丙沙星栓。观察各组疗效并加以分析。结果 对于混合性宫颈阴道炎的治疗,联合治疗组的疗效优于单纯用药组。结论 联合用     

祛浊散瘀汤治疗慢性前列腺炎41例

目的 :探讨通淋化浊、活血祛瘀类中药配伍治疗慢性前列腺炎的临床疗效。方法 :对 78例慢性前列腺炎患者分成两组 ,治疗组 41例 ,服用祛浊散瘀汤 (牛膝、丹参、桃仁、酒大黄、红花、红藤、白花蛇舌草等 ) ;对照组 37例 ,服用前列康片。结果 :用药 2个月后 ,治疗组总有效率 90 .2 % ,对照组总有效率 70 .3% ,差异有显著意义 ( P<0 .0 1 )。提示 :祛浊散瘀汤具有祛瘀散浊、活血化瘀、清热解毒的作用。     

园背角无齿蚌抗肿瘤有效成份的研究——Ⅱ HB-Ⅰ蛋白聚酶的分离、纯化

对园背角无齿蚌抗肿瘤有效组份HB的分离、纯化进行了研究,获得3个纯品,分别定名为HB-Ⅰa、HB-Ⅰb、HB-Ⅰc,分子量分别为6.7万D、6.95万D和6.62万D。     

X型沸石改性及失活的研究——催化甲醇与甲苯侧链烷基化反应

本文研究了在甲醇与甲苯侧链的烷基化反应中,K_2B_4O_7(Ⅰ)与H_3BO_3-MgO(Ⅱ)对X型沸石催化剂的改性规律。用Ⅰ对KX沸石进行改性,当每100gKX沸石含3.12×10~(-2)mol K_2B_4O_7时,甲醇的选择性较好;用Ⅱ进行改性,每100gKX沸石含0.8mol MgO及0.19mol H_3BO_3时,产品中苯乙烯的含量及苯乙烯与乙苯的产率都较高。当采用H_3BO_3-MgO-Cs X型催化剂时,甲醇转化率和选择性分别达到88%及27%,苯乙烯及乙苯的产率达到0.63(g/gCat·h)。同时对X型沸石催化剂失活进行了研究,认为除了结焦导致失活外,反应过程中产生的水蒸汽使沸石的结构和性能受到破坏,亦导致失活。     

脑立神的研制及其临床应用

作者研制了中成药制剂——脑立神口服液(简称NLS),主要用于治疗颅脑损伤后综合征、脑血管病后遗症、颈椎病伴椎基动脉供血不足症等。其治则为活血化瘀、镇静安神、健脾强心、补心益血。内蒙古沙土鼠药效试验证实脑立神可提高沙土鼠的耐缺血,缺氧能力,经临床应用202例,对照服药前后患者症状、体征结合部份患者r-CBF、TCD、CT等检测总有效率96％,表明脑立神口服液在治疗颅脑损伤后综合征、脑血管病后遗症等脑病有疗效。