HEMOCONCENTRATION AND PLASMA VOLUME EXPANSION THERAPY IN SEVERE PREGNANCY INDUCED HYPERTEN- SION

Sixty-two patients with pregnancy induced hy- pertension (PIH) were analysed retrospectively and 32 randomly selected normal healthy pregnant women from 16th gestational week till full term were studied for prospective PIH. The results showed that severe preeclampsia was characterized by he moconcentration and high blood viscosity several weeks before the clinical manifestation of hyperten sion as indicated by serial theological determinations. Four cases of preeclampsia with stormy courses had persistant hemoconcentration. Two cases with pro gressivc increase of theological parameters develop- ed eclampsia. This denotes that hemoconcentration is pathological and requires plasma volume expan sion following adequate treatmcnt with antispas- motics. Severe PIH patients are prone to be cojw plicated by pulmonary edema. To minimize the risk, it is necessary to give effective and adequate dose of MgS04 first, followed by expansion therapy if indicated. Colloids are preferable to crystalloids. Following this rule, we have not encountered any iatrogenic pulmonary edema in severe preeclampsia.     

神经母细胞瘤下领骨转移1例

患儿男，11个月。因左面部膨隆1个月，于2004年9月16日入院。患儿1个月前发现左下颌膨隆，近5d生长迅速，自用消炎药物（具体不详）治疗无效。患儿病程中无发热及渐进性消瘦，既往史及家庭史无特殊。查体：心肺无异常，腹部无包块，可触及肝脾肿大，质硬。专科见面部不对称，左下颌骨膨隆明显，局部皮肤无红肿、破溃，质硬，边界不清，双侧颌下、颈部以及腋窝、腹股沟可触及多个肿大的淋巴结，活动，质中等。余无明显异常。CT示：下颌骨周边软组织肿胀，颌骨增生，有放射状肿瘤新生骨生成，并可见骨质吸收改变，另可见上颌骨、颞骨、颧骨虫蚀样溶骨性骨质破坏。X线胸片：未见异常。诊断：颌骨恶性肿瘤。为明确诊断于2004年9月21日行颌下淋巴结活检术，病理诊断为神经母细胞瘤转移。     

THE VALUE OF AMNIOCENTESIS IN THE MANAGEMENT OF HIGH RISK PREGNANCY

Amniotic fluid analysis involving 119 tapings was performed in 95 high risk pregnancy patients from March 1980 to October 1981. This is, at present, the most accurate method for assessing fetal maturity. The accuracy of the L/S ratio, foam test and creatine value was 96.98'70, 94.89'70 and 86.6%, respectively. The stt:tdy shows that amniotic fluid analysis plays an essential role in the planned delivery of high risk pregnancies. Intra-amniotic administration of dexamethasone can promote fetal maturity and is also very important in the management of the Condition.     

简易的产时评分法—预测产程中高危的发生

许多作者报导妊娠期高危评分法可预测围产期死亡,又有些学者进行产程中的高危评分,并认为两者结合使用,可使其预测性更为准确。目前妊娠期的高危评分的预测性能达到满意的结果,但对产程中的评分因素尚有争论,争论的关键在于有些评分因素虽可证实胎儿处于危险状态,但已无足够的时间进行转院,抢救或进行高危因素转化治疗。本文的目的是从三方面来检验简易的产时评分是否能预测产程顺利与否,即围产死亡率,围产病率及母亲病率(以剖腹或中位产钳分娩的发生率来表示);另一方面分析联合采用产前评分法和产时评分法对高危孕妇,高危产妇的转化治疗是否有指导作用。本文分析了1,994例产妇,按产时评分≥3为高     

羊角拗甙剂治疗55例心力衰竭之临床疗效初步观察报告

前言 毒毛旋花子素k治疗心力衰竭有很高的疗效,最近国内学者已有许多报告①②③④,它系由一种夹桃竹科(Apocynaceae)植物康毗毒毛旋花的种子中所提炼出的甙类。但这种植物产于非洲,因此我国现在所用的该药,均需依靠进口,不仅需耗用外汇,且常有供应不足之患;故诚如苏联华     

银杏达莫注射液的主动及被动过敏性反应评价

目的：通过动物实验评价银杏达莫注射液引起过敏反应的风险。方法：通过腹腔注射银杏达莫注射液致敏豚鼠和大鼠,14 d后,静脉注射致敏豚鼠并收集血清皮内注射正常大鼠,做豚鼠的全身主动过敏和大鼠的皮肤被动过敏,评价银杏达莫注射液引起过敏反应的风险。结果：经银杏达莫注射液致敏和激发的豚鼠未出现全身主动过敏反应（n=6）;应用经银杏达莫注射液致敏大鼠的血清,被动致敏正常大鼠,经银杏达莫注射液激发后,亦未见皮肤被动过敏反应（n=6）。结论：动物实验显示银杏达莫注射液引起过敏反应的风险较小。     

谁是谁的刻骨铭心

Chapter 1夕阳西落,晚霞恋恋不舍地飘走最后一抹彩色,也带走了一天的燥热。无聊至极的我趴在房间冰透的大理石地板上百无聊赖地翻看初中时的同学录。直到大学毕业了,本就集体意识不强的兰屿高中07级5班都没有举办过一次同学会,再加上两年前班主任的意外去世,重聚的想法就变得更淡薄了。后来我又丢了手机,QQ被盗,完完全全与过去斩断了联系,我甚至开始忘记昔日同窗的脸孔,忘记那些散发着爆米花甜香的青春韶光。     

胰腺癌患者血循环miR-429的表达及其临床意义

目的:检测胰腺癌患者血浆miR-429表达水平,分析其表达与胰腺癌临床病理学特征的关系。方法:定量PCR检测BXPC-3、PANC-1细胞株以及3例胰腺癌组织中miR-429的表达水平。收集未经治疗的37例胰腺癌患者的血浆标本,采用实时定量PCR法检测miR-429表达水平,收集胰腺癌患者的临床病理学参数(年龄、临床分期、分化程度、组织类型及淋巴结转移情况),比较不同miR-429水平的临床病理参数分布差异。结果:相较于正常胰腺细胞、胰腺组织,miR-429在胰腺癌细胞株和癌组织中均处于低表达水平(P<0.05)。miR-429表达与肿瘤大小、TNM临床分期、神经浸润以及生存期密切相关,均有统计学差异(P<0.05)。结论:循环血miR-429的表达可能成为胰腺癌早期诊断、预后判断的指标。