全文获取类型
收费全文 | 2382篇 |
免费 | 71篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 83篇 |
妇产科学 | 9篇 |
基础医学 | 334篇 |
口腔科学 | 50篇 |
临床医学 | 126篇 |
内科学 | 650篇 |
皮肤病学 | 20篇 |
神经病学 | 200篇 |
特种医学 | 49篇 |
外科学 | 369篇 |
综合类 | 13篇 |
预防医学 | 27篇 |
眼科学 | 8篇 |
药学 | 202篇 |
中国医学 | 4篇 |
肿瘤学 | 308篇 |
出版年
2023年 | 12篇 |
2022年 | 26篇 |
2021年 | 48篇 |
2020年 | 13篇 |
2019年 | 35篇 |
2018年 | 26篇 |
2017年 | 22篇 |
2016年 | 34篇 |
2015年 | 31篇 |
2014年 | 54篇 |
2013年 | 70篇 |
2012年 | 102篇 |
2011年 | 118篇 |
2010年 | 77篇 |
2009年 | 67篇 |
2008年 | 143篇 |
2007年 | 138篇 |
2006年 | 134篇 |
2005年 | 147篇 |
2004年 | 157篇 |
2003年 | 167篇 |
2002年 | 169篇 |
2001年 | 33篇 |
2000年 | 20篇 |
1999年 | 34篇 |
1998年 | 58篇 |
1997年 | 35篇 |
1996年 | 41篇 |
1995年 | 20篇 |
1994年 | 58篇 |
1993年 | 54篇 |
1992年 | 34篇 |
1991年 | 26篇 |
1990年 | 25篇 |
1989年 | 18篇 |
1988年 | 21篇 |
1987年 | 18篇 |
1986年 | 19篇 |
1985年 | 13篇 |
1984年 | 12篇 |
1983年 | 7篇 |
1982年 | 19篇 |
1981年 | 15篇 |
1980年 | 19篇 |
1979年 | 8篇 |
1977年 | 8篇 |
1976年 | 7篇 |
1974年 | 6篇 |
1958年 | 6篇 |
1956年 | 6篇 |
排序方式: 共有2466条查询结果,搜索用时 421 毫秒
71.
Itamar Harel Yoshiro Maezawa Roi Avraham Ariel Rinon Hsiao-Yen Ma Joe W. Cross Noam Leviatan Julius Hegesh Achira Roy Jasmine Jacob-Hirsch Gideon Rechavi Jaime Carvajal Shubha Tole Chrissa Kioussi Susan Quaggin Eldad Tzahor 《Proceedings of the National Academy of Sciences of the United States of America》2012,109(46):18839-18844
72.
Is a composite score of physical performance measures more useful than usual gait speed alone in assessing functional status? 总被引:1,自引:0,他引:1
Seino S Kim MJ Yabushita N Nemoto M Jung S Osuka Y Okubo Y Matsuo T Tanaka K 《Archives of gerontology and geriatrics》2012,55(2):392-398
Overall physical performance can be represented by a composite score that is derived from upper and lower extremity performance measures. We aimed to identify whether composite scores of performance measures, particularly the lower extremity performance (LEP) score, upper extremity performance (UEP) score, and an overall score, are more accurate than usual gait speed (UGS) for assessing a wide range of functional status. We conducted a cross-sectional analysis on data from 701 community-dwelling older women (mean age 74.3 years). Trained testers measured UGS and the seven tests included in the composite scores. Using self-reported questionnaires, we assessed multiphasic functional status: physical function, higher-level functional capacity, mobility limitation, activities of daily living (ADLs), and falls. We compared the areas under the receiver operating characteristic curves (AUCs) of UGS with LEP, UEP, and overall scores for each status. We found no significant differences between the AUCs of UGS and LEP score for each status. The UEP score had significantly smaller AUCs for low physical function (0.73) and mobility limitation (0.78) than UGS alone (0.81 and 0.85, respectively), and the differences were substantial. Although the overall score had significantly greater AUCs for low higher-level functional capacity (0.83) and ADLs disability (0.83) than UGS alone (0.78 and 0.80, respectively), the differences were only 3-5%. The UGS should not be regarded solely as a measure of lower extremity function; this single test may represent overall physical performance. The UGS alone, which can be measured quickly and easily, suffice for assessing a wide range of functional status in older women. 相似文献
73.
74.
75.
Robert F. Spetzler Richard A. Roski Herbert Schuster Yoshiro Takaoka 《Neurological research》2013,35(1):345-359
AbstractExtracranial to intracranial bypass surgery was used in 27 cases of intracranial giant aneurysm to prevent ischemic complications. In 19 of 21 patients the aneurysm was considered unfit for a direct clipping or ligation, and an EC-IC bypass was done in conjunction with staged clipping of the internal carotid artery or occlusion of the middle cerebral artery. All bypass grafts have remained patent postoperatively. None of the patients have developed ischemic complications in the 6-41 month period of follow-up. 相似文献
76.
Yuji Shingu Shunichiro Komatsu Shinji Norimizu Yoshiro Taguchi Eiji Sakamoto 《Surgical endoscopy》2016,30(2):526-531
Background
The concept of laparoscopic subtotal cholecystectomy (LSC), without approaching Calot’s triangle to avoid both laparotomy and serious complications, is not widely accepted. In this study, we evaluated the outcomes of LSC for severe cholecystitis when dissection of the cystic duct and cystic artery is hazardous.Methods
From January 2004 to December 2013, 110 consecutive patients who underwent LSC without ligation of the cystic duct and vessels were enrolled in this retrospective study. Their clinical records, including operative records and outcomes, had been entered into a prospectively maintained database and were analyzed.Results
The mean operating time and blood loss were 121 min and 33.8 ml, respectively. All LSCs were completed without conversion to an open procedure. No injuries to the bile duct or vessels were experienced. Postoperative complications occurred in ten (9.1 %) patients, including subhepatic hematoma in 3, bile leakage in 3, and subhepatic abscess in 1. Patients recovered from complications without requiring re-operation. During follow-up periods (mean 30.7 months), symptomatic biliary stone diseases relapsed in three patients (2.7 %) and were successfully treated by endoscopic management.Conclusions
LSC without an attempt to dissect Calot’s triangle is a safe and feasible procedure that can avoid conversion to laparotomy.77.
78.
Developmental shift in GABA actions from depolarization to hyperpolarization occurs as a result of decreasing the intracellular Cl(-) concentration regulated by K(+)-Cl(-) co-transporter 2 (KCC2). To clarify the time-course of the developmental shift on the Purkinje cells, we examined KCC2-localization in the embryonic mouse cerebellum. The KCC2 was first detected within the Purkinje cells in the Purkinje cell layer of the hemisphere at embryonic day 15 (E15) and the vermis at E17, but the ventricular and intermediate zones were negative. These results suggest that GABA might become inhibitory on the Purkinje cells after their settling in the Purkinje cell layer. 相似文献
79.
Three cases of colon cancer accompanied by unusual abscess formation are reported. Case I : A 77-year-old man was diagnosed with a paracolic abscess formation behind the cecum and a swollen appendix by computed tomography (CT) scan. Case II : An 85-year-old woman was diagnosed with an abscess formation of the right iliopsoas muscle, a swollen appendix, and a thickened right colon wall by CT scan. After antibiotic therapy failed, both patients underwent ileocecal resection urgently under suspicion of appendicitis, but cecal cancer around the entrance to the appendix caused secondary appendicitis in both cases. Case III : A 50-year-old woman was diagnosed with sigmoid colon cancer with an abscess formation in the pelvic cavity concomitant with ovarian tumor. A Hartmann procedure was performed, and a pathological examination revealed that a subserosal abscess behind the sigmoid colon cancer perforated the rectum with abscess formation. All cases were definitively diagnosed intraoperatively. The cancer recurred in cases I and III. We emphasize that precise surgical evaluation has an important role in the diagnosis of these complicated diseases. In addition, surgery affords the patient the best chance of recovery, and in these advanced cases radical treatment is recommended as early as possible. 相似文献
80.
Kikuchi Y Hirota M Iwai T Aoki S Chikumaru H Kawabe R Matsui Y 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(3):e41-e46
Salivary duct carcinoma (SDC) is a distinctive and aggressive neoplasm. The most frequent site of origin is the parotid gland, followed by the submandibular gland. SDC originating in the minor salivary glands, particularly in the ectopic glands within the mandible, is extremely rare. We describe a 62-year-old man with SDC in the mandible, who presented with a painless lump in the right submandibular region (later identified as lymph node metastasis) and ipsilateral mental nerve palsy. Histologic examination after ablative surgery revealed SDC originating in the mandible and cervical nodal metastases spreading to levels I-III. The patient remains alive 59 months after presentation as a result of postoperative full-dose irradiation and regular intensive chemotherapy using TXT, 5-FU, and CDDP. However, the patient has local recurrence and distant metastases to the lung and brain. In this report, we also discuss the specific diagnostic criteria and developmental theories of intraosseous salivary gland tumors. 相似文献