全文获取类型
收费全文 | 11007篇 |
免费 | 818篇 |
国内免费 | 217篇 |
专业分类
耳鼻咽喉 | 234篇 |
儿科学 | 520篇 |
妇产科学 | 362篇 |
基础医学 | 489篇 |
口腔科学 | 361篇 |
临床医学 | 1780篇 |
内科学 | 2579篇 |
皮肤病学 | 194篇 |
神经病学 | 619篇 |
特种医学 | 401篇 |
外科学 | 2753篇 |
综合类 | 108篇 |
预防医学 | 436篇 |
眼科学 | 558篇 |
药学 | 241篇 |
中国医学 | 5篇 |
肿瘤学 | 402篇 |
出版年
2023年 | 161篇 |
2022年 | 95篇 |
2021年 | 173篇 |
2020年 | 181篇 |
2019年 | 170篇 |
2018年 | 261篇 |
2017年 | 295篇 |
2016年 | 326篇 |
2015年 | 326篇 |
2014年 | 426篇 |
2013年 | 574篇 |
2012年 | 484篇 |
2011年 | 477篇 |
2010年 | 451篇 |
2009年 | 533篇 |
2008年 | 571篇 |
2007年 | 559篇 |
2006年 | 585篇 |
2005年 | 496篇 |
2004年 | 370篇 |
2003年 | 325篇 |
2002年 | 257篇 |
2001年 | 221篇 |
2000年 | 173篇 |
1999年 | 230篇 |
1998年 | 205篇 |
1997年 | 224篇 |
1996年 | 320篇 |
1995年 | 263篇 |
1994年 | 203篇 |
1993年 | 125篇 |
1992年 | 132篇 |
1991年 | 150篇 |
1990年 | 73篇 |
1989年 | 129篇 |
1988年 | 104篇 |
1987年 | 81篇 |
1986年 | 100篇 |
1985年 | 83篇 |
1984年 | 88篇 |
1983年 | 74篇 |
1982年 | 66篇 |
1981年 | 63篇 |
1980年 | 81篇 |
1978年 | 59篇 |
1977年 | 43篇 |
1976年 | 43篇 |
1975年 | 46篇 |
1964年 | 49篇 |
1963年 | 47篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
22.
Z Yilmaz T Renton Y Yiangou J Zakrzewska I P Chessell C Bountra P Anand 《Journal of clinical neuroscience》2007,14(9):864-871
Burning mouth syndrome (BMS) is often an idiopathic chronic and intractable pain condition, affecting 1.5-5.5% of middle-aged and elderly women. We have studied the heat and capsaicin receptor TRPV1, and its regulator nerve growth factor (NGF), in BMS. Patients with BMS (n=10) and controls (n=10) were assessed for baseline and post-topical capsaicin pain scores, and their tongue biopsies immunostained for TRPV1, NGF, and structural nerve markers neurofilament and peripherin. Nerve fibres penetrating the epithelium were less abundant in BMS (p<0.0001), indicating a small fibre neuropathy. TRPV1-positive fibres were overall significantly increased in BMS (p=0.0011), as were NGF fibres (p<0.0001) and basal epithelial cell NGF staining (p<0.0147). There was a significant correlation between the baseline pain score and TRPV1 (p=0.0143) and NGF fibres (p=0.0252). A significant correlation was observed between baseline and post-capsaicin pain (p=0.0006). Selective TRPV1 and NGF blockers may provide a new therapy for BMS. 相似文献
23.
LY Chow MRCPsych D Chung MRCPsych V Leung MB BS TF Leung MB ChB CM Leung MRCPsych 《International journal of clinical practice》1997,51(5):330-331
Akathisia as a side-effect of metoclopramide has received increasing attention in consultation-liaison psychiatry in recent years. A case of metoclopramide-induced akathisia resulting in a suicide attempt is reported in order to highlight the suffering of such patients and the factors that lead to misdiagnosis. 相似文献
24.
25.
26.
S. H. CRAY MB BS FRCA J.L. DIXON MB BS FRCA C.M.B. HEARD MB BS FRCA D.S. SELSBY MB BS FRCA 《Paediatric anaesthesia》1996,6(4):265-270
Forty-nine children having day-stay surgical procedures were randomly assigned to receive oral midazolam 0.75 mg·kg?1 or placebo in a double blind fashion. The child's level of anxiety was assessed before premedication using parental, child and observer scales. The child and observer anxiety scores were repeated in the anaesthetic room. Most children presented for anaesthesia in a calm state, irrespective of whether they had received midazolam. Parents tended to overestimate their child's level of anxiety. Observer anxiety scores reliably predicted behaviour during induction of anaesthesia in the absence of a sedative. Observer scores decreased in the midazolam group (P<0.02), but not in the placebo group, children below six years having the greatest decrease with midazolam. The median time to discharge from hospital was delayed by 30 min in the midazolam group (P<0.01). Children do not require routine sedative premedication for day case procedures, but oral midazolam is useful in producing calm behaviour in those children with high observer anxiety scores. 相似文献
27.
John D. Hughes MD Changyi Chen MD Samer G. Mattar MB ChB Ayten Someren MD Beverly Noe BS Carolyn R. Suwyn BS Alan B. Lumsden MD 《Annals of vascular surgery》1996,10(2):123-130
Hypothermia and preservative perfusates have been used to decrease ischemic renal injury. This study was performed to identify the preservative function of perfusates independent of the effects of hypothermia. Rats underwent 45 minutes of renal ischemia. Rectal and renal parenchyma temperatures were monitored and maintained within 1° C of normal. Perfusates were University of Wisconsin solution (UW), Euro-Collins solution, normal saline solution, and Ringer's lactate solution. A nonperfused ischemic control and a nonischemic control group were also evaluated. Parameters evaluated included serum creatinine and blood urea nitrogen levels, renal ischemic injury grade, renal weight, and gross appearance of the injured kidney. Rats treated with UW solution were found to have a significantly lower creatinine, blood urea nitrogen, and injury grade than the other three perfused groups. The external gross appearance of the UW-treated kidneys was normal, whereas that of the other groups demonstrated moderate to severe injury. Although the mean right/left renal weight difference of the UW-treated group was lower than that of the other three groups, this was not statistically significant. Under normothermic conditions in rats, UW solution affords significant renal protection from ischemia. Euro-Collins, normal saline, and Ringer's lactate solutions display no significant protective effect.Presented at the Twentieth Annual Meeting of the Peripheral Vascular Surgery Society, New Orleans, La., June 10, 1995. 相似文献
28.
M J Ahern MD FRACP M Wetherall BEd A Leslie MB BS R H James BSc P J Roberts-Thomson PhD FRACP G C Rennie BA BSc MA 《International journal of clinical practice》1992,46(4):229-233
The elderly (age >65 years) are more vulnerable to side-effects induced by non-steroidal anti-inflammatory drugs (NSAIDs). We therefore performed a double-blind comparative study of ketoprofen SR and sulindac in patients with active rheumatoid arthritis, 65 years of age or older. Sulindac was chosen because of its possible renal sparing effects, and ketoprofen SR because of its short half life and sustained release delivery system. Eighty patients were entered. More patients withdrew from the study due to side-effects in the sulindac group; both treatment groups had a high incidence of side-effects during this study and during previous exposure to other NSAIDs, demonstrating that the elderly are susceptible to side-effects from NSAIDs. 相似文献
29.
N. D. Edwards MB BS FRCAnaes M. Hartley MB P. Clyburn MB BS FRCAnaes M. Harmer MB BS FRCAnaes 《Anaesthesia》1992,47(5):435-437
A double-blind randomised study was performed to assess the value of the addition of pethidine 50 mg to the initial dose of bupivacaine given for epidural analgesia in labour. Forty-nine patients received either 1 ml of saline (n = 24), or 50 mg of pethidine (n = 25), added to 9 ml of 0.25% bupivacaine as an initial injection for intrapartum epidural analgesia. There was a significant increase in the mean duration of analgesia in the pethidine group. However, pethidine did not increase the speed of onset of analgesia, or improve the quality of analgesia. 相似文献
30.