全文获取类型
收费全文 | 2584篇 |
免费 | 160篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 77篇 |
妇产科学 | 57篇 |
基础医学 | 433篇 |
口腔科学 | 56篇 |
临床医学 | 158篇 |
内科学 | 548篇 |
皮肤病学 | 37篇 |
神经病学 | 163篇 |
特种医学 | 134篇 |
外科学 | 370篇 |
综合类 | 134篇 |
一般理论 | 1篇 |
预防医学 | 144篇 |
眼科学 | 43篇 |
药学 | 209篇 |
中国医学 | 14篇 |
肿瘤学 | 189篇 |
出版年
2024年 | 3篇 |
2023年 | 20篇 |
2022年 | 54篇 |
2021年 | 68篇 |
2020年 | 34篇 |
2019年 | 66篇 |
2018年 | 61篇 |
2017年 | 43篇 |
2016年 | 72篇 |
2015年 | 103篇 |
2014年 | 162篇 |
2013年 | 153篇 |
2012年 | 191篇 |
2011年 | 219篇 |
2010年 | 136篇 |
2009年 | 115篇 |
2008年 | 136篇 |
2007年 | 146篇 |
2006年 | 146篇 |
2005年 | 103篇 |
2004年 | 90篇 |
2003年 | 93篇 |
2002年 | 72篇 |
2001年 | 55篇 |
2000年 | 41篇 |
1999年 | 47篇 |
1998年 | 36篇 |
1997年 | 25篇 |
1996年 | 25篇 |
1995年 | 19篇 |
1994年 | 24篇 |
1993年 | 13篇 |
1992年 | 21篇 |
1991年 | 19篇 |
1990年 | 15篇 |
1989年 | 23篇 |
1988年 | 22篇 |
1987年 | 18篇 |
1986年 | 9篇 |
1985年 | 13篇 |
1984年 | 14篇 |
1983年 | 5篇 |
1982年 | 16篇 |
1981年 | 7篇 |
1980年 | 6篇 |
1976年 | 3篇 |
1968年 | 3篇 |
1967年 | 2篇 |
1966年 | 3篇 |
1965年 | 2篇 |
排序方式: 共有2784条查询结果,搜索用时 0 毫秒
61.
Configuration Interaction in the Calculation of Oscillatory and Rotatory Intensities of Nonplanar pi-Electronic Systems 下载免费PDF全文
Cheong KK Oshita A Caldwell DJ Eyring H 《Proceedings of the National Academy of Sciences of the United States of America》1970,67(4):1727-1733
The interaction of configurations, including all possible singly excited configurations, is incorporated into the calculation of oscillatory and rotatory intensities of simple nonplanar π-electronic systems such as skewed butadiene and acrolein. The results are discussed in terms of the reliability of the (self-consistent field)-(linear combination of atomic orbitals)-(molecular orbital) wave functions employed. 相似文献
62.
63.
Joo An Hwang Kee Bum Kim Min Jae Yang Sun Gyo Lim Jae Chul Hwang Jae Youn Cheong Sung Won Cho Soon Sun Kim 《Clinical and molecular hepatology》2015,21(2):131-140
Background/Aims
To determine the efficacies of entecavir (ETV) in nucleos(t)ide analogue (NA)-naïve chronic hepatitis B (CHB) patients and in those with prior lamivudine (LAM) use who did not develop resistance.Methods
We retrospectively enrolled 337 patients with CHB who were treated with ETV (0.5 mg daily) for at least 30 months. The study included 270 (80.1%) NA-naïve patients and 67 (19.9%) LAM-use patients. Ten of the LAM-use patients were refractory to LAM therapy without developing resistance.Results
Genotypic resistance to ETV developed more frequently in the LAM-use group (13.1%) than in the NA-naïve group (2.6%) at 60 months (P=0.009). In subgroup analysis, after excluding the 10 patients who were refractory to LAM therapy, the cumulative probability of ETV resistance did not differ significantly between the two groups (P=0.149). Prior LAM refractoriness and a higher hepatitis B virus DNA level at month 12 were independent predictive factors for the development of ETV resistance.Conclusions
ETV resistance developed more frequently in LAM-use patients with CHB. However, prior LAM use without refractoriness did not affect the development of ETV resistance. The serum hepatitis B virus DNA level at month 12 was a major predictor for the development of ETV resistance. 相似文献64.
Ohnishi in 1975 first described temporomandibular joint (TMJ) arthroscopy. Along with its extensive use, a range of complications has emerged. We describe a patient who experienced parapharyngeal swelling after undergoing arthroscopy. Prolonged intubation up to 1 hour postoperatively was required. The swelling resolved completely over 6 h without further intervention. 相似文献
65.
Differentiating hepatic portal venous gas (HPVG) and pneumobilia on the CT scan can be accomplished by comparing the pattern of intrahepatic air spread. HPVG can be an indicator of significant intra‐abdominal pathology and bowel ischaemia is the most common causative etiology for HPVG. 相似文献
66.
Pradeep Kumar Sharma Bhaskar Saikia Rachna Sharma Kumar Ankur Praveen Khilnani Vinay Kumar Aggarwal Hae Cheong 《Indian journal of pediatrics》2014,81(10):1095-1098
Bartter syndrome is a group of inherited, salt-losing tubulopathies presenting as hypokalemic metabolic alkalosis with normotensive hyperreninemia and hyperaldosteronism. Around 150 cases have been reported in literature till now. Mutations leading to salt losing tubulopathies are not routinely tested in Indian population. The authors have done the genetic analysis for the first time in the Bartter syndrome on two cases from India. First case was antenatal Bartter syndrome presenting with massive polyuria and hyperkalemia. Mutational analysis revealed compound heterozygous mutations in KCNJ1(ROMK) gene [p(Leu220Phe), p(Thr191Pro)]. Second case had a phenotypic presentation of classical Bartter syndrome however, genetic analysis revealed only heterozygous novel mutation in SLC12A gene p(Ala232Thr). Bartter syndrome is a clinical diagnosis and genetic analysis is recommended for prognostication and genetic counseling. 相似文献
67.
Jae Youn Cheong Hyoung Doo Shin Sung Won Cho Yoon Jun Kim 《Journal of Korean medical science》2014,29(11):1523-1527
MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the development to hepatocellular carcinoma (HCC) in patients with chronic HBV infection. A total of 1,439 subjects, who have either past or present HBV infection, were enrolled and divided into four groups (spontaneous recovery, chronic HBV carrier without cirrhosis, liver cirrhosis and HCC). We genotyped the precursor miR-604 genome region polymorphism. The CC genotype of miR-604 rs2368392 was most frequently observed and T allele frequency was 0.326 in all study subjects. The HBV persistence after infection was higher in those subjects with miR-604 T allele (P=0.05 in a co-dominant and dominant model), which implied that the patients with miR-604 T allele may have a higher risk for HBV chronicity. In contrast, there was a higher rate of the miR-604 T allele in the chronic carrier without HCC patients, compared to those of the HCC patients (P=0.03 in a co-dominant model, P=0.02 in a recessive model). The T allele at miR-604 rs2368392 may be a risk allele for the chronicity of HBV infection, but may be a protective allele for the progression to HCC in chronic HBV carriers.
Graphical Abstract
相似文献68.
69.
70.