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61.
Mohan Kameshwaran Kiran Natarajan Anand Kumar George Thomas Sathiya Murali 《Indian journal of otolaryngology and head and neck surgery》2003,55(3):196-199
Giant glomus tumors pose a challenge to the Otologist by virtue of their location and vascularity. A vast majority of them
present with tinnitus, conductive hearing loss and cranial nerve palsies. We report the case of a 16-year-old male patient
who presented with sudden right-sided sensorineural hearing loss. This is an unusual presentation of a giant glomus tumor.
We present the clinical features and management of this unusual case. 相似文献
62.
Sathanandam S Anand Subramanyam N Murthy Vishal S Vaidya Moiz M Mumtaz Harihara M Mehendale 《Food and chemical toxicology》2003,41(8):1123-1132
The objective of this study was to evaluate the interaction profile of chloroform (CHCl(3))+allyl alcohol (AA) binary mixture (BM)-induced acute hepatotoxic response. Plasma alanine aminotransferase (ALT) was measured to assess liver injury, and 3H-thymidine (3H-T) incorporation into hepatonuclear DNA was measured as an index of liver regeneration over a time course of 0-72 h. Male Sprague-Dawley (S-D) rats received single ip injection of 5-fold dose range of CHCl(3) (74, 185 and 370 mg/kg) in corn oil (maximum 0.5 ml/kg) and 7-fold dose range of AA (5, 20 and 35 mg/kg) in distilled water simultaneously. The doses for BM were selected from individual toxicity studies of CHCl(3) alone [Int. J. Toxicol. 22 (2003) 25], and AA alone [Reg. Pharmacol. Toxicol. 19 (1999) 165]. Since the highest dose of each treatment (CHCl(3)- 740 and AA- 50 mg/kg) yielded mortality due to the suppressed tissue repair followed by liver failure, this dose was omitted for BM. The levels of CHCl(3) (30-360 min) and AA (5-60 min) were quantified in blood and liver by gas chromatography (GC). The liver injury was more than additive after BM compared to CHCl(3) alone or AA alone at highest dose combination (370+35 mg/kg), which peaked at 24 h. The augmented liver injury observed with BM was consistent with the quantitation data. Though the liver injury was higher, the greater stimulation of tissue repair kept injury from progressing, and rescued the rats from hepatic failure and death. At lower dose combinations, the liver injury was no more than additive. Results of the present study suggest that liver tissue repair, in which liver tissue lost to injury is promptly replaced, plays a pivotal role in the final outcome of liver injury after exposure to BM of CHCl(3) and AA. 相似文献
63.
64.
P. M. Parikh S. H. Advani J. S. Nadkarni S. Kulkarni G. Kapoor P. S. R. K. Sastry M. Anand T. K. Saikia R. Gopal 《Cancer investigation》1997,15(4):326-328
Hepatic veno-occlusive disease (VOD) is the second most common cause of death after autologous bone marrow transplantation (ABMT). A patient with multiple myeloma undergoing ABMT developed classic features of hepatic VOD. He responded to treatment with pentoxiphyllin. Serum tumor necrosis factor (TNF) levels showed remarkable correlation with the severity of VOD and response to therapy. 相似文献
65.
Arti Kapil Sumeeta Gulati Vikas Goel Lalit Kumar Rakhee Krishnan V Kochupillai 《Medical oncology (Northwood, London, England)》1998,15(4):270-274
Acinetobacter baumannii is emerging as a major cause of nosocomial infections particularly in high risk patients. Being resistant to adverse environmental
conditions, it can stay for prolonged periods in the hospital environment. We report an outbreak in the medical oncology ward
where nine patients suspected of bacteraemia were blood culture positive forA. baumannii from the two samples each, one collected through the i.v. cannula and another through the peripheral venous puncture. The
bacteria was also isolated from the environmental sources from the various samples collected. The biotype, antibiogram, cellular
protein profiles on SDS-PAGE and the restriction enzyme analysis patterns of the patient isolates and the environmental isolates
were similar. This points to the environment as a source of infection. With reinforcement of proper barrier nursing and use
of disposable heparine ampoules it was possible to control the outbreak. 相似文献
66.
David K Warren Anand Nitin Cheri Hill Victoria J Fraser Marin H Kollef 《Infection control and hospital epidemiology》2004,25(2):99-104
OBJECTIVE: To determine the occurrence of co-colonization or co-infection with VRE and MRSA among medical patients requiring intensive care. DESIGN: Prospective, single-center, observational study. SETTING: A 19-bed medical ICU in an urban teaching hospital. PATIENTS: Adult patients requiring at least 48 hours of intensive care and having at least one culture performed for microbiologic evaluation. RESULTS: Eight hundred seventy-eight consecutive patients were evaluated. Of these patients, 402 (45.8%) did not have microbiologic evidence of colonization or infection with either VRE or MRSA, 355 (40.4%) were colonized or infected with VRE, 38 (4.3%) were colonized or infected with MRSA, and 83 (9.5%) had co-colonization or co-infection with VRE and MRSA. Multiple logistic regression analysis demonstrated that increasing age, hospitalization during the preceding 6 months, and admission to a long-term-care facility were independently associated with colonization or infection due to VRE and co-colonization or co-infection with VRE and MRSA. The distributions of positive culture sites for VRE (stool, 86.7%; blood, 6.5%; urine, 4.8%; soft tissue or wound, 2.0%) and for MRSA (respiratory secretions, 34.1%; blood, 32.6%; urine, 17.1%; soft tissue or wound, 16.2%) were statistically different (P < .001). CONCLUSIONS: Co-colonization or co-infection with VRE and MRSA is common among medical patients requiring intensive care. The recent emergence of vancomycin-resistant Staphylococcus aureus and the presence of a patient population co-colonized or co-infected with VRE and MRSA support the need for aggressive infection control measures in the ICU. 相似文献
67.
T. S Anand Ritu Mittal T. B. Shashidhar R. K. Sharma 《Indian journal of otolaryngology and head and neck surgery》2006,58(4):402-404
Massive vascular malformation involving tongue can cause significant functional impairment. In this report we describe a rare
case of extensive venous malformation involving tongue leading to obstructive sleep apnoea, inability to speak, eat, severe
discomfort due to exposure induced dryness and ulceration. Multimodality treatment approach comprising of sclerotherapy, electrocautery
and radiation therapy was used in this case. 相似文献
68.
Mohan Kameswaran M. C. Vasudevan R. S. Anand Kumar Jawahar Nagasundaram Kiran Natarajan S. Raghunandhan 《Indian journal of otolaryngology and head and neck surgery》2005,57(1):58-63
Multichannel auditory brainstem implants (ABI) are currently indicated for patients with neurofibromatosis type II (NF2) involving both vestibulocochlear nerves. The ABI helps bypass the damaged cochlear nerves and restores a level of auditory sensation via the electrical stimulation of the cochlear nucleus. The implant is usually placed in the lateral recess of the fourth ventricle at the time of tumor resection to stimulate the cochlear nucleus. We report a case of ABI done on a 15-year-old girl with bilateral vestibular schwannomas. 相似文献
69.
Vikas A. Gupta Shannon M. Matulis Benjamin G. Barwick R. Devin Bog Conrad W. Shebelut Mala Shanmugam Paola Neri Nizar J. Bahlis Madhav V. Dhodapkar Leonard T. Heffner Craig C. Hofmeister Nisha S. Joseph Sagar Lonial Jonathan L. Kaufman David L. Jaye Ajay K. Nooka Lawrence H. Boise 《Blood cancer journal》2022,12(8)
70.
A. Danielle Iuliano Joan M. Brunkard Tegan K. Boehmer Elisha Peterson Stacey Adjei Alison M. Binder Stacy Cobb Philip Graff Pauline Hidalgo Mark J. Panaggio Jeanette J. Rainey Preetika Rao Karl Soetebier Susan Wacaster ChinEn Ai Vikas Gupta Noelle-Angelique M. Molinari Matthew D. Ritchey 《MMWR. Morbidity and mortality weekly report》2022,71(4):146