吸烟对前庭眼动影响的研究

实验采用正弦摆动模式的前庭刺激方法,对8名健康男性青年吸烟者吸烟前后视前庭眼动各参数进行观察。结果表明:吸烟后即刻视网膜电位降低非常显著(P<0.01),慢相速度及增益增大非常显著(P<0.01),快相速度增大显著(P<0.05);在吸烟后30min时均未完全恢复,但已无显著差异(P>0.05)。提示:吸烟可 以导致空中盲距增大、夜间视力降低及空晕病、前庭本体性错觉的发生,对飞行安全构成严重威胁。     

模拟失重膳食Fe摄入及血清蛋白含量的变化

目的　探讨模拟失重膳食 Fe摄入量及蛋白质含量的变化 .方法　受试者 - 6°头低位卧床 2 1d,用称量法观察其营养素及 Fe摄入量的变化 ,并于卧床前 2 d,卧床 1,11和 2 1d测定血红蛋白 (Hb) ;用双缩脲法及溴甲酚绿法分别测定血清总蛋白及白蛋白含量 .结果　膳食 Fe摄入量 2 wk开始降低 16 % ,3wk后基本恢复 ,血清总蛋白也在 2 wk降低 5 % (P<0 .0 5 ) ,3wk回升 ,Hb不受影响 .结论　模拟失重对膳食Fe摄入量及总蛋白含量有短期影响 ,经过适应期后可恢复到正常范围     

诺氟沙星微囊包囊率及收率的测定

采用6种不同溶剂-非溶剂制备诺氟沙星微囊,并测定包囊率和收率.结果表明,选用二氯甲烷-正已烷制备诺氟沙星微囊其包囊率在6种溶剂-非溶剂组成中最高,达90.90%,收率也较高为87.27%.     

Bichat guidelines for the clinical management of brucellosis and bioterrorism-related brucellosis

Interest in Brucella species as a biological weapon stems from the fact that airborne transmission of the agent is possible. It is highly contagious and enters through mucous membranes such as the conjunctiva, oropharynx, respiratory tract and skin abrasions. It has been estimated that 10-100 organisms only are sufficient to constitute an infectious aerosol dose for humans. Signs and symptoms are similar in patients whatever the route of transmission and are mostly non-specific. Symptoms of patients infected by aerosol are indistinguishable from those of patients infected by other routes. Regimens containing doxycycline plus streptomycin or doxycycline plus rifampin are effective for most forms of brucellosis. Isolation of patients is not necessary. Trimethoprim-sulfamethoxazole and fluoroquinolones also have good results against Brucella, but are associated with high relapse rates when used as monotherapy. The combination of ofloxacin plus rifampicin is associated with good results. Even if there is little evidence to support its utility for post-exposure prophylaxis, doxycycline plus rifampicin is recommended for 3 to 6 weeks.     

茶树籽对钉螺生殖腺和肝脏的影响

目的 :了解钉螺组织经茶树籽处理的影响。方法 :应用电镜技术观察处理后的钉螺肝脏及生殖腺组织的超微结构。结果 :钉螺在茶树籽作用 2 4 h后 ,肝内细胞受损。雄性生殖细胞有凝固性及溶解性变化 ;成熟精子细胞膜肿胀与内部结构分离 ,线粒体鞘呈现凝集型 ,支持细胞可见凝固性改变 ,且彼此断裂并与生殖细胞分离。雌性钉螺生殖腺可见卵细胞肿胀 ,严重时滤泡细胞有破裂 ,卵细胞膜则可丧失完整性。结论 :茶树籽能损伤钉螺的生殖腺和肝脏。     

DNA探针用于中华按蚊和嗜人按蚊的分类研究

本项研究首次报道了我国中华按蚊和嗜人按蚊DNA基因库的建立,并从中华按蚊DNA基因库中筛选出一特异的DNA片段,以此为DNA探针,分别与中华按蚊DNA和嗜人按蚊DNA进行斑点杂交试验,其结果证明该DNA探针可与任何发育期的中华按蚊DNA杂交而不与嗜人按蚊DNA杂交,该探针敏感性高,可检测出7.5ng的中华按蚊DNA,大约相当于1个蚊虫总DNA的1/150,可用于区别中华按蚊和嗜人按蚊。     

Practice parameters for the identification and testing of patients at risk for dominantly inherited colorectal cancer--supporting documentation

It should be recognized that these guidelines should not be deemed inclusive of all proper methods of care or exclusive of methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propriety of any specific procedure must be made by the physician in light of all of the circumstances presented by the individual patient. Prepared By The Standards Task Force The American Society of Colon and Rectal Surgeons     

日本血吸虫大陆株副肌球蛋白部分基因克隆

目的 :克隆日本血吸虫大陆株副肌球蛋白部分基因。方法 :用 PCR方法根据已发表日本血吸虫菲律宾株副肌球蛋白基因部分核苷酸序列扩增大陆株副肌球蛋白基因。结果 :获得一日本血吸虫大陆株 72 0 bp基因克隆。结论 :经核苷酸序列分析证实 ,本克隆基因与菲律宾株基因核苷酸同源性为 99.0 3%。