全文获取类型
收费全文 | 3696篇 |
免费 | 267篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 53篇 |
儿科学 | 93篇 |
妇产科学 | 96篇 |
基础医学 | 498篇 |
口腔科学 | 45篇 |
临床医学 | 348篇 |
内科学 | 865篇 |
皮肤病学 | 100篇 |
神经病学 | 443篇 |
特种医学 | 110篇 |
外科学 | 334篇 |
综合类 | 31篇 |
一般理论 | 1篇 |
预防医学 | 338篇 |
眼科学 | 91篇 |
药学 | 197篇 |
中国医学 | 5篇 |
肿瘤学 | 329篇 |
出版年
2024年 | 6篇 |
2023年 | 55篇 |
2022年 | 112篇 |
2021年 | 229篇 |
2020年 | 95篇 |
2019年 | 134篇 |
2018年 | 153篇 |
2017年 | 107篇 |
2016年 | 106篇 |
2015年 | 117篇 |
2014年 | 174篇 |
2013年 | 190篇 |
2012年 | 284篇 |
2011年 | 318篇 |
2010年 | 150篇 |
2009年 | 142篇 |
2008年 | 224篇 |
2007年 | 248篇 |
2006年 | 212篇 |
2005年 | 185篇 |
2004年 | 161篇 |
2003年 | 125篇 |
2002年 | 122篇 |
2001年 | 33篇 |
2000年 | 23篇 |
1999年 | 36篇 |
1998年 | 16篇 |
1997年 | 12篇 |
1996年 | 15篇 |
1995年 | 11篇 |
1994年 | 10篇 |
1993年 | 9篇 |
1992年 | 10篇 |
1991年 | 7篇 |
1990年 | 7篇 |
1989年 | 5篇 |
1988年 | 5篇 |
1986年 | 11篇 |
1985年 | 9篇 |
1984年 | 7篇 |
1983年 | 7篇 |
1978年 | 8篇 |
1977年 | 5篇 |
1974年 | 5篇 |
1973年 | 7篇 |
1972年 | 7篇 |
1971年 | 5篇 |
1969年 | 5篇 |
1967年 | 7篇 |
1966年 | 7篇 |
排序方式: 共有3977条查询结果,搜索用时 15 毫秒
31.
32.
33.
34.
Jana Ihlow Sophia Gross Leonie Busack Anne Flrcken Julia Jesse Michaela Schwarz Nina Rosa Neuendorff Ann-Christin von Brünneck Ioannis Anagnostopoulos Seval Türkmen Igor Wolfgang Blau Thomas Burmeister David Horst Lars Bullinger Jrg Westermann 《Haematologica》2022,107(8):1773
In acute myeloid leukemia, there is an ongoing debate on the prognostic value of the early bone marrow assessment in patients receiving intensive therapy. In this retrospective study, we analyzed the prognostic impact of the early response in 1,008 patients with newly diagnosed acute myeloid leukemia, who were treated at our institution with intensive chemotherapy followed by consolidation chemotherapy and/or allogeneic hematopoietic stem cell transplantation (HSCT). We found that early blast persistence has an independent negative prognostic impact on overall survival, event-free survival and relapse-free survival. This negative prognostic impact may only be overcome in patients showing at least a partial remission at the early bone marrow assessment and who subsequently achieve blast clearance by additional induction chemotherapy prior to consolidation therapy with allogeneic HSCT. In accordance, we propose that the time slope of remission is an additional leukemia-related dynamic parameter that reflects chemosensitivity and thus may inform post-induction therapy decision-making. In addition to patient-related factors, European LeukemiaNet risk group, measurable residual disease monitoring and donor availability, this may particularly apply to European LeukemiaNet intermediate-risk patients, for whom a decision between consolidation chemotherapy and allogeneic HSCT remains challenging in many cases. 相似文献
35.
Yamada Shinichi Takahashi Shun Malchow Berend Papazova Irina Stöcklein Sophia Ertl-Wagner Birgit Papazov Boris Kumpf Ulrike Wobrock Thomas Keller-Varady Katriona Hasan Alkomiet Falkai Peter Wagner Elias Raabe Florian J. Keeser Daniel 《European archives of psychiatry and clinical neuroscience》2022,272(6):957-969
European Archives of Psychiatry and Clinical Neuroscience - Significant evidence links white matter (WM) microstructural abnormalities to cognitive impairment in schizophrenia (SZ), but the... 相似文献
36.
37.
Sophia Wong Fady Hannah-Shmouni Graham Sinclair Sandra Sirrs Marshall Dahl Andre Mattman 《Clinical biochemistry》2013,46(1-2):180-183
ObjectivesTo examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status.Design and methodsSerum acylcarnitine levels were measured in hypo- and hyperthyroid subjects before and after treatment with thyroxine or thionamide therapy respectively.ResultsNo discernible differences were observed in the serum acylcarnitine profiles between hypo-, hyper- and euthyroid states.ConclusionsAcylcarnitine profiles are relatively unremarkable in thyroid disease. 相似文献
38.
Sophia A. Traven Russell A. Reeves Molly G. Sekar Harris S. Slone Zeke J. Walton 《The Journal of arthroplasty》2019,34(1):140-144
Background
While the 11-factor modified frailty index (mFI) has been shown to predict adverse outcomes in patients undergoing total joint arthroplasty, the 5-factor index has not been evaluated in this patient population. The goal of this study was to evaluate the utility of the mFI-5 as a predictor of morbidity and mortality in patients undergoing primary total hip and knee arthroplasty.Methods
A retrospective analysis of the American College of Surgeons National Surgical Quality Improvement Program's database for patients undergoing total hip arthroplasty and total knee arthroplasty between the years 2005 and 2016 was conducted. The 5-factor score, which includes the presence of comorbid diabetes, hypertension, congestive heart failure, chronic obstructive pulmonary disease, and functional status, was calculated for each patient. Multivariate logistic regression models were used to assess the relationship between the mFI-5 and postoperative complications while controlling for demographic variables.Results
One hundred forty thousand one hundred fifty-eight patients undergoing total hip arthroplasty and 226,398 patients undergoing total knee arthroplasty were identified. After adjusting for demographic variables and comorbid conditions, logistic regression analyses revealed that the mFI-5 was a strong predictor for total complications, Clavien-Dindo grade IV complications (cardiac arrest, myocardial infarction, septic shock, pulmonary embolism, postoperative dialysis, reintubation, and prolonged ventilator requirement), surgical site infections, readmission, and 30-day mortality (P < .001).Conclusions
The mFI-5 is an independent predictor of postoperative complications including life-threatening medical complications, surgical site infections, hospital readmission, and 30-day mortality after primary hip and knee arthroplasty. This clinical tool can be used to identify high-risk surgical patients and guide preoperative counseling to optimize outcomes.Level of Evidence
III. 相似文献39.
Wind-borne insects mediate directional pollen transfer between desert fig trees 160 kilometers apart
Sophia Ahmed Stephen G. Compton Roger K. Butlin Philip M. Gilmartin 《Proceedings of the National Academy of Sciences of the United States of America》2009,106(48):20342-20347
The question of how far pollen can move between plants has implications for topics as diverse as habitat fragmentation, conservation management, and the containment of genetically modified crops. The monoecious African fig tree Ficus sycomorus L. relies on the small, short-lived, night-flying, host-specific fig wasp Ceratosolen arabicus Mayr for pollination. We used microsatellite markers to characterize a geographically isolated riparian population of F. sycomorus growing along the Ugab River in the Namib Desert, Namibia, together with paternity analysis of seedlings from known mothers, to map pollen movement within this population. In this way we tracked insect movements between individually recognizable trees by means of their pollen cargo and documented the movement of C. arabicus between known trees separated by more than 160 km, with a mean distance for confirmed successful pollination events of 88.6 km. The predominant observed movement of pollinators was in a westerly direction, toward the sea, reflecting seasonal nighttime wind direction and the wind-borne dispersal of fig wasps. Our results suggest the existence of an extensive panmictic population of trees that are well suited to overcome the effects of geographical isolation. 相似文献
40.
Dimitrios Papadimas Tilemachos Paraskeuopoulos Sophia Anagnostopoulou 《Clinical anatomy (New York, N.Y.)》2009,22(7):826-833
Bilateral dissection of 15 formalin embalmed cadaver legs was performed in order to study the anatomic pattern of the peroneal artery (PA) and its cutaneous perforating vessels (CB). The total number of CB from the PA was 125 or an average of 4.17 branches per leg. CB were distributed in the superoinferior axis between 18.25 and 84.25% of the length of the fibula and their average length was 5 ± 1.8 cm. 86/125 (68.8%) of the CB were classified as myocutaneous branches (MC) that penetrated muscle before reaching the skin, whereas 39/125 (31.2%) were septocutaneous branches (SC) that passed through the intermuscular septum. The mean distance between the posterior border of the fibula and the site where the perforators emerged was 1.88 ± 0.79 cm for the SC and 1.21 ± 0.87 cm for the MC. These anatomic findings should encourage the surgeon to design the skin paddle in the boundary between the middle and the distal third of the fibular length about 2 cm behind the posterior fibular border on the posterolateral leg, where the number of CB is maximal. Clin. Anat. 22:826–833, 2009. © 2009 Wiley‐Liss, Inc. 相似文献