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981.
AbstractBackground: The association between the Joint Committee on Infant Hearing (JCIH) risk factors and etiology of hearing loss (HL) is not studied well in children.Objectives: To clarify the etiologic causes and evaluate the JCIH risk characteristics of children with HL.Methods: A retrospective study of 296 children with HL born between 2009.01 and 2013.12 in Stokholm. Demographic data, family and medical histories, audiologic results, imaging findings, and genetic results were ascertained and analyzed.Results: In 221 with bilateral hearing loss (BHL), family history and neonatal risk indicators were the most common risks (59 each), followed by syndrome related risks. In 75 with unilateral hearing loss (UHL), craniofacial anomaly was the most common risk, followed by family history. Etiology was established in 93 with BHL, in which syndromic HL accounted for 37.2%, chromosomal aberrations for 21.3%, and environmental causes for 19.1%. Etiology was established in 35 with UHL, in which ear malformation accounted for the most (74.3%), followed by environmental causes (14.3%).Conclusions and significance: Childhood HL can be attributed to a variety of causes with an etiology identifiable in 42.5% of BHL and 46.7% of UHL. BHL and UHL have different patterns of JCIH risk exposure and etiology. 相似文献
982.
Sara R. Jaffee 《Journal of child psychology and psychiatry, and allied disciplines》2020,61(3):215-217
The start of a new decade is often the moment when people pause to reflect on what they have accomplished in the past 10–20 years and where they would like to be at the start of the next decade. Although not designed as such, the 2020 Annual Review issue engages in exactly this sort of a backwards and forwards look at the field of child and adolescent psychiatry and psychology. In doing so, it covers topics that are at the core of the field and have preoccupied researchers and clinicians for decades. It also covers research endeavors that have only more recently captured the attention of the field and that build bridges to disciplines that have not historically been involved in the study of neurodevelopment. In every case, the authors who have contributed to the 2020 Annual Research Review highlight exciting new directions for research and make novel recommendations for how to advance the state of our science. 相似文献
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985.
Catherine Bland Kathryn V. Dalrymple Sara L. White Amanda Moore Lucilla Poston Angela C. Flynn 《Maternal & child nutrition》2020,16(2)
The importance of diet during pregnancy is critically important for the short‐ and long‐term health of both mother and child. The number of apps targeting pregnant women is rapidly increasing, yet the nutritional content of these tools remains largely unexplored. This review aimed to evaluate the coverage and content of nutrition information in smartphone apps available to U.K. pregnant women. Keyword searches were conducted in iTunes and Google Play stores in November 2018. Candidate apps were included if they targeted pregnant women, provided pregnancy‐specific nutritional information, had a user rating of at least 4+ based on at least 20 ratings, and were available in English. Nutritional content was assessed for accuracy against U.K. recommendations. Behaviour change techniques (BCTs) were also evaluated. Twenty‐nine apps were included, seven of which originated in the United Kingdom. There was a large variability in the quality of smartphone app nutritional information. The accuracy of nutrition information varied, and several apps conveyed inappropriate information for pregnancy. On average, 10 BCTs were identified per app (range 2–15). Overall, smartphone apps do not consistently provide accurate and useful nutritional information to pregnant women. This study highlights the need for the integration of evidence‐based nutritional information during app development and for increased regulatory oversight. App developers should also make it clear that nutritional content is intended for a specific geographical region or population or modify for the intended audience. These are important considerations for the design of future apps, which are increasingly used to complement existing maternity services. 相似文献
986.
Panicker Jalesh N. Simeoni Sara Miki Yasuo Batla Amit Iodice Valeria Holton Janice L. Sakakibara Ryuji Warner Thomas T. 《Journal of neurology》2020,267(3):659-664
Journal of Neurology - Lower urinary tract (LUT) dysfunction presents early in multiple system atrophy (MSA), usually initially as urinary urgency, frequency and incontinence, and voiding... 相似文献
987.
Tikoo Sankalp Pietracupa Sara Tommasin Silvia Bologna Matteo Petsas Nikolas Bharti Komal Berardelli Alfredo Pantano Patrizia 《Journal of neurology》2020,267(5):1358-1367
Journal of Neurology - Despite previous functional MRI studies on alterations within the cerebello-thalamo-cortical circuit in patients with essential tremor (ET), the specific role of... 相似文献
988.
Castelnuovo Alessandra Marelli Sara Mombelli Samantha Salsone Maria Ferini-Strambi Luigi 《Journal of neurology》2020,267(7):2157-2158
Journal of Neurology - 相似文献
989.
Elfil Mohamed Ahmed Nada Alapati Amritha Bahekar Rucha Kandil Mohamed Kim Christine Schaefer Sara Tinaz Sule Patel Amar S. de Figueiredo John M. Louis Elan D. Koo Brian B. 《Journal of neurology》2020,267(4):966-974
Journal of Neurology - We aimed to determine suicide risk and lifetime suicidal ideation in Parkinson disease (PD) patients versus controls and how depression, demoralization, and insomnia are... 相似文献
990.
M. Angela Cenci MD PhD Sara Riggare MSci Rajesh Pahwa MD David Eidelberg MD Robert A. Hauser MD 《Movement disorders》2020,35(3):392-396
Levodopa-induced dyskinesia (LID) represents a significant source of discomfort for people with Parkinson's disease (PD). It negatively affects quality of life, it is associated with both motor and nonmotor fluctuations, and it brings an increased risk of disability, balance problems, and falls. Although the prevalence of severe LID appears to be lower than in previous eras (likely owing to a more conservative use of oral levodopa), we have not yet found a way to prevent the development of this complication. Advanced surgical therapies, such as deep brain stimulation, ameliorate LID, but only a minority of PD patients qualify for these interventions. Although some have argued that PD patients would rather be ON with dyskinesia than OFF, the deeper truth is that patients would very much prefer to be ON without dyskinesia. As researchers and clinicians, we should aspire to make that goal a reality. To this end, translational research on LID is to be encouraged and persistently pursued. © 2019 International Parkinson and Movement Disorder Society 相似文献