全文获取类型
收费全文 | 1217篇 |
免费 | 76篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 19篇 |
妇产科学 | 19篇 |
基础医学 | 139篇 |
口腔科学 | 19篇 |
临床医学 | 197篇 |
内科学 | 275篇 |
皮肤病学 | 23篇 |
神经病学 | 115篇 |
特种医学 | 46篇 |
外科学 | 138篇 |
综合类 | 2篇 |
预防医学 | 138篇 |
眼科学 | 10篇 |
药学 | 71篇 |
中国医学 | 1篇 |
肿瘤学 | 90篇 |
出版年
2023年 | 15篇 |
2022年 | 28篇 |
2021年 | 57篇 |
2020年 | 37篇 |
2019年 | 36篇 |
2018年 | 39篇 |
2017年 | 34篇 |
2016年 | 37篇 |
2015年 | 44篇 |
2014年 | 49篇 |
2013年 | 78篇 |
2012年 | 92篇 |
2011年 | 90篇 |
2010年 | 54篇 |
2009年 | 49篇 |
2008年 | 80篇 |
2007年 | 74篇 |
2006年 | 62篇 |
2005年 | 77篇 |
2004年 | 79篇 |
2003年 | 39篇 |
2002年 | 54篇 |
2001年 | 11篇 |
2000年 | 6篇 |
1999年 | 7篇 |
1998年 | 6篇 |
1997年 | 3篇 |
1996年 | 3篇 |
1995年 | 5篇 |
1994年 | 2篇 |
1993年 | 4篇 |
1992年 | 4篇 |
1991年 | 6篇 |
1990年 | 6篇 |
1989年 | 3篇 |
1988年 | 6篇 |
1987年 | 2篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1976年 | 1篇 |
1975年 | 4篇 |
1974年 | 1篇 |
1970年 | 1篇 |
1969年 | 2篇 |
1968年 | 4篇 |
1959年 | 1篇 |
排序方式: 共有1303条查询结果,搜索用时 15 毫秒
11.
12.
13.
14.
15.
Jonathan Bryant-Genevier Carol Y. Rao Barbara Lopes-Cardozo Ahoua Kone Charles Rose Isabel Thomas Diana Orquiola Ruth Lynfield Dhara Shah Lori Freeman Scott Becker Amber Williams Deborah W. Gould Hope Tiesman Geremy Lloyd Laura Hill Ramona Byrkit 《MMWR. Morbidity and mortality weekly report》2021,70(26):947
16.
Gabrielle C Baxter Andrew J Patterson Ramona Woitek Iris Allajbeu Martin J Graves Fiona Gilbert 《The British journal of radiology》2021,94(1119)
Objective:To compare diffusion-weighted images (DWI) acquired using single-shot echo-planar imaging (ss-EPI) and multiplexed sensitivity encoding (MUSE) in breast cancer.Methods20 females with pathologically confirmed breast cancer (age 51 ± 12 years) were imaged with ss-EPI-DWI and MUSE-DWI. ADC, normalised ADC (nADC), blur and distortion metrics and qualitative image quality scores were compared. The Crété-Roffet and Mattes mutual information metrics were used to evaluate blurring and distortion, respectively. In a breast phantom, six permutations of MUSE-DWI with varying parallel acceleration factor and number of shots were compared. Differences in ADC and nADC were compared using the coefficient of variation in the phantom and a paired t-test in patients. Differences in blur, distortion and qualitative metrics were analysed using a Wilcoxon signed-rank test.Results:There was a low coefficient of variation (<2%) in ADC between ss-EPI-DWI and all MUSE-DWI permutations acquired using the phantom. 22 malignant and three benign lesions were identified in 20 patients. ADC values measured using MUSE were significantly lower compared to ss-EPI for malignant but not benign lesions (p < 0.001, p = 0.21). nADC values were not significantly different (p = 0.62, p = 0.28). Blurring and distortion improved with number of shots and acceleration factor, and significantly improved with MUSE in patients (p < 0.001, p = 0.002). Qualitatively, image quality improved using MUSE.Conclusion:MUSE improves the image quality of breast DWI compared to ss-EPI.Advances in knowledge:MUSE-DWI has superior image quality and reduced blurring and distortion compared to ss-EPI-DWI in breast cancer. 相似文献
17.
18.
DeLario MR Sheehan AM Ataya R Bertuch AA Vega C Webb CR Lopez-Terrada D Venkateswaran L 《American journal of hematology》2012,87(5):461-464
Primary myelofibrosis is a chronic myeloproliferative neoplasm characterized by cytopenias, leukoerythroblastosis, extramedullary hematopoiesis, hepatosplenomegaly and bone marrow fibrosis. Primary myelofibrosis is a rare disorder in adults; children are even less commonly affected by this entity, with the largest pediatric case series reporting on three patients. Most literature suggests spontaneous resolution of myelofibrosis without long term complications in the majority of affected children. We describe the clinical, pathologic, and molecular characteristics and outcomes of nineteen children with primary myelofibrosis treated in our center from 1984 to 2011. Most patients had cytopenia significant enough to require supportive therapy. No child developed malignant transformation and only five of the 19 children (26%) had spontaneous resolution of disease. Sequence analyses for JAK2V617F and MPLW515L mutations were performed on bone marrow samples from 17 and six patients, respectively, and the results were negative. In conclusion, analysis of this large series of pediatric patients with primary myelofibrosis demonstrates distinct clinical, hematologic, bone marrow, and molecular features from adult patients. 相似文献
19.
Jeremias Hey Johannes Seidel Ramona Schweyen Yvonne Paelecke-Habermann Dirk Vordermark Christian Gernhardt Thomas Kuhnt 《Clinical oral investigations》2013,17(6):1619-1625