内蒙古自治区智力残疾现患率调查及病因分析

目的:了解内蒙古自治区智力残疾(mental retardation.MR)的现患率及其分布特点,分析其主要致残原因构成特点,探讨预防治疗措施。方法:采用概率比例、多阶段分层整群抽样方法进行现况调查及病例对照研究,根据年龄分别使用丹佛发育筛查测验及《7岁以上人群残疾筛查问卷》筛查,分别使用Gesell发育诊断量表及韦氏儿童智力量表简式(WISC-CR),韦氏成人智力量表简式(WAIS-RC)进行智力诊断,采用SPSS11.0软件对数据进行统计分析。结果:①内蒙古自治区智力残疾患者的现患率为4.95‰,男性MR现患率高于女性(χ2=6.28,df=1,P<0.05),农村MR的现患率明显高于城市(χ2=60.035,df=1,P<0.01)。②内蒙古自治区智力残疾致残原因以疾病(29.26%)和遗传因素(23.79%)为主。③在18岁之前(智力发育期)发现智力残疾的占74.53%,且以0~3岁发现智力残疾的人数比例最高(48.84%)。结论:智力残疾的防治重点应在农村,预防应以疾病(主要包括脑疾病、内分泌障碍、惊厥性疾病)及遗传因素为主。强调早期发现、早期干预。     

Ten-year survival in 290 patients with endometrial cancer: prognostic factors and therapeutic approach

Summary. Between 1970 and 1976, 290 patients with endometrial cancer were treated at the 1st Obstetrics and Gynecology Clinic of the University of Milan. The median age was 62 years. Surgery was completed in 262 (90.3%) patients. Abdominal hysterectomy was used in 158 (70.9%) stage I and 40 (71.4%) stage II/III patients; vaginal hysterectomy in 55 (24.7%) stage I and nine (16.1%) stage II/III patients. Resection of the upper vagina was performed in 168 patients. Postoperative external beam radiotherapy was used in stage II/III patients and in 44 (19.7%) stage I high-risk patients. Ten-year survival, determined by the life-table method, was 84.8% in stage I (223 patients), 53.4% in stage II (37 patients), 64.4% in stage III (19 patients), and 9.1% in stage IV (11 patients). Factors associated with poorer prognosis were: late age at diagnosis (P<0.001); deep myometrial invasion (P<0.001); poorly differentiated histological grade ( P =0.11); lack of resection of the upper vagina ( P = 0.13). The role and importance of surgery is discussed, with special emphasis on the selective use of the vaginal route in aged, obese and medically high-risk patients.     

Influence of margin design and taper abutment angle on a restored crown of a first premolar using finite element analysis

PURPOSE: The purpose of this study was to determine the influence of margin design and taper abutment angle on the stresses developed in all-ceramic first premolar crowns. MATERIALS AND METHODS: Four margin designs and three taper abutment angles were independently incorporated into models examined by finite element analysis. A 600-N force was applied vertically downward. RESULTS: The taper abutment angle had a significant influence on the greatest peak tensile maximum principal stresses (sigma11) in the coping (16.8% change in stress for an 8-degree variation in taper angle). The margin design had significant influence on the highest peak tensile sigma11 in the dentin (60% difference in stress between designs) and lesser significance in the cement (30%). All calculated values of the highest peak tensile sigma11 were considerably lower than the fracture strengths of the respective materials in which the stresses resided. CONCLUSION: A smaller taper abutment angle and a larger chamfer radius (equivalent to the modified light chamfer) are recommended to reduce the magnitude of the greatest peak tensile sigma11 based on the finite element modeling conducted.     

Influence of cement on a restored crown of a first premolar using finite element analysis

PURPOSE: The purpose of this study was to examine the influence of the elastic modulus of cement and luting thickness on the resulting stresses in an axially loaded crown cemented onto a first premolar. A comparison of these stresses was also made with the strength of the constituent materials making up the crown. MATERIALS AND METHODS: Examination of the stresses on a restored crown was conducted using finite element analysis. Eight different axisymmetric models containing combinations of In-Ceram or gold coping, using adhesive resin or zinc phosphate cement as the luting agent, with thicknesses of either 0.05 or 0.1 mm were analyzed. RESULTS: The peak tensile principal stresses in the porcelain remained below its material fracture strength. The same was true for the peak stress in the adhesive resin compared to its fracture and chemical bond strength. This was not the case for zinc phosphate. The influence of the luting agent's elastic modulus on the stresses in the crown was minor, and the influence of luting thickness was even less. CONCLUSION: The role of the luting agent was primarily one that effectively transferred the resulting stresses between the relatively stiff coping and underlying dentin. There was no evidence of the luting agent itself playing a significant role in resisting deflection from the applied force.     

Preliminary report on the validation of a grammar-based computer system for assessing skeletal maturity with the Tanner-Whitehouse 2 method

A series of hand and wrist radiographs was assessed manually by two individuals and by a fully automated computer system for determining bone age. Assessments were repeated after 1 month to determine variability between and within the methods of bone age assessment. There was slight intra-observer variation, but complete reproducibility when assessments were made by computer. The variation between the human assessors was less than that between human and computer assessments. The difference between overall maturity scores made by the human observer and the computer system was, however, acceptably small, and the majority of assessments were the same. It is concluded this computer system for assessing bone age in normal children is reliable and accurate, but that it needs to be validated against a much larger set of radiographs.