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71.
Mohammad Shahidi‐Dadras Behnaz Hamedani Nasim Niknezhad Nasim Ghilizadeh 《Dermatologic therapy》2019,32(5)
Rosai‐Dorfman disease (RDD) is a rare disease which characterized by proliferation and overproduction of histiocytes in the lymph nodes appearing as lymphadenopathy, however, it may also occur in extranodal sites. The occurrence of unusual manifestations of the disease such as the appearance of the mass in an unusual area may increase the probability of misdiagnosis. Herein, we describe a case of RDD in an old woman with an unusual appearance of RDD in the leg that was successfully treated by thalidomide. 相似文献
72.
Maryam Golmohammadi Dalia Ahmed Elmaghraby Andrés Alexis Ramírez-Coronel Nodir Rakhimov Shahad Saad Mohammed Rosario Mireya Romero-Parra Mohammed Abed Jawad Mohammad Yasin Zamanian Afsaneh Soltani Niloofar Taheri Farzaneh Kianifar Nasim Vousooghi 《Fundamental & clinical pharmacology》2023,37(5):900-909
Bladder cancer (BC) is known as a prevalent genitourinary malignancy and has a significant mortality rate worldwide. Despite recent therapeutic approaches, the recurrence rate is high, highlighting the need for a new strategy to reduce the BC cell progression. Quercetin, a flavonoid compound, demonstrated promising anticancer properties and could be used in the management of various malignancies such as BC. This comprehensive review summarized quercetin's cellular and molecular mechanisms underlying anticancer activities. The study's findings indicated that quercetin prevents the proliferation of the human BC cell line, promotes apoptosis of BIU-87 cells, reduces the expression of p-P70S6K, and induces apoptosis by p-AMPK. Moreover, quercetin restricts tumor growth through the AMPK/mTOR cascade and prevents colony formation of human BC cells by triggering DNA damage. Studying this review article will help researchers better understand quercetin's functional role in the prevention and treatment of BC. 相似文献
73.
Mycobacterium bovis BCG cell wall-specific differentially expressed genes identified by differential display and cDNA subtraction in human macrophages 下载免费PDF全文
74.
Hassan Mirmohammad Sadeghi Nafise Shamloo Nasim Taghavi Yaser Safi Farzad Aghdashi Mohammad Ismaeilnejad 《Journal of maxillofacial and oral surgery》2015,14(3):836-840
Osteomas are benign slow growing tumors of bone. Tumors are usually asymptomatic until they attain remarkable size and cause asymmetry or dysfunction. In view of few reported cases of giant osteoma of mandible, this article presents a case of giant osteoma of left mandible in a 53-year old male causing dyspnea due to compression of air way space. 相似文献
75.
76.
Ali Almasirad Abbas Shafiee Mohammad Abdollahi Amir Noeparast Nasir Shahrokhinejad Nasim Vousooghi Sayyed Abbas Tabatabai Reza Khorasani 《Medicinal chemistry research》2011,20(4):435-442
A series of new 1,3,4-oxadiazoles and 1,2,4-triazoles were synthesized in order to obtain new compounds with potential analgesic
activity. Compounds were evaluated for their analgesic activities by formalin-induced nociception test. Mefenamic acid (as
the reference drug) did not show any activity in the early phase of the formalin test, while compounds 7b, 7c, 8c, and 9a significantly reduced the nociception in this phase. However in the late phase of formalin test all of the target compounds
and mefenamic acid showed analgesic activity in comparison to control. 相似文献
77.
Nasim Hedayati M.D. Dan X. Cai M.D. Ph.D. Christopher R. McHenry M.D. 《Journal of gastrointestinal surgery》2003,7(6):802-804
A subdiaphragmatic, retroperitoneal bronchogenic cyst arising from the stomach is reported in a patient who was referred for
evaluation of what was thought to be an adrenal tumor. To our knowledge, less than 20 cases of retroperitoneal bronchogenic
cyst have been reported in the English literature. A bronchogenic cyst may be indistinguishable from an adrenal tumor and,
although rare, should be considered in the differential diagnosis of a retroperitoneal mass. 相似文献
78.
Interferon gamma (IFN-gamma) and nitric oxide (NO) are the major players of the host defense against Leishmania. In the present study circulating levels of IFN-gamma, NO, interleukin (IL)-6 and C-reactive protein (CRP) were compared in kala azar (KA), post-kala azar dermal leishmaniasis (PKDL) and healthy controls. A significantly elevated level of these parameters was evident in KA compared to PKDL or control. Further, significantly elevated levels of IFN-gamma, NO and CRP were observed in sodium antimony gluconate (SAG) unresponsive cases compared to responsive cases. In PKDL cases, NO was significantly elevated while other parameters were comparable to control. At post-treatment stage, KA patients showed a significant decrement in all the parameters, however, IL-6 and CRP remained above control level. Hence, data implies that the parasites survive in spite of the presence of effector molecules, and the excessive release of IFN-gamma and NO could be associated with the progression of the disease. 相似文献
79.
80.
Autosomal Recessive Nonsyndromic Arrhythmogenic Right Ventricular Cardiomyopathy without Cutaneous Involvements: A Novel Mutation 下载免费PDF全文
Mahdieh Soveizi Bahareh Rabbani Yousef Rezaei Sedigheh Saedi Nasim Najafi Majid Maleki Nejat Mahdieh 《Annals of human genetics》2017,81(4):135-140
The arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic disease frequently associated with desmosomal mutations, mainly attributed to dominant mutations in the Plakophilin‐2 (PKP2) gene. Naxos and Carvajal are the syndromic forms of ARVD/C due to recessive mutations. Herein, we report an autosomal recessive form of nonsyndromic ARVD/C caused by a mutation in the PKP2 gene. After examination and implementation of diagnostic modalities, the definite diagnosis of ARVD/C was confirmed by detection of ventricular tachycardia with a left bundle branch configuration and a superior axis, T‐wave inversion in right precordial leads (i.e., V1‐V3) in a 12‐lead electrocardiogram, and a right ventricle outflow tract dilatation. Neither cutaneous involvement nor other abnormalities were observed. Genetic testing was performed during which an intronic mutation of c.2577+1G>T in the PKP2 gene was observed homozygously. The c.2577+1G>T disrupts PKP2 mRNA splicing and causes a nonsyndromic form of ARVD/C. 相似文献