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Srinivas U Pillai L Kar R Mahapatra M Gujra S Pati HP 《Indian journal of pathology & microbiology》2007,50(4):917-919
Non-hematopoietic malignancies infiltrating bone marrow have always been a source of erroneous diagnosis. Among these, the small round cell tumors like neuroblastomas and rhabdomyosarcomas mimick the hematopoietic blasts. Several case reports of rhabdomyosarcoma mimicking acute leukemia, clinically and morphologically at presentation have been reported in the literature. To the best of our knowledge such an entity has not been reported in Indian literature. We report here one such case of alveolar rhabdomyosarcoma masquerading as acute leukemia. A thorough clinical examination with high degree of suspicion on bone marrow morphology and judicious use of appropriate immunohistochemistry markers will solve many of these cases. 相似文献
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Antonio Suppa MD PhD Luca Marsili MD Flavio Di Stasio MD Anna Latorre MD AK. Parvez MBBS Carlo Colosimo MD Alfredo Berardelli MD 《Movement disorders》2014,29(1):97-104
In humans, intermittent and continuous theta‐burst stimulation (iTBS and cTBS) elicit long‐term changes in motor‐evoked potentials (MEPs) reflecting long‐term potentiation (LTP)‐ and depression (LTD)‐like plasticity in the primary motor cortex (M1). In this study, we used TBS to investigate M1 plasticity in patients with MSA. We also assessed whether responses to TBS reflect M1 excitability as tested by short‐interval intracortical inhibition (SICI), intracortical facilitation (ICF), short‐interval intracortical facilitation (SICF), and the input/output curves. We studied 20 patients with MSA and 20 healthy subjects (HS). Patients were clinically evaluated with the Unified Multiple System Atrophy Rating Scale. The left M1 was conditioned with TBS. Twenty MEPs were recorded from the right first dorsal interosseous muscle before TBS and 5, 15, and 30 minutes thereafter. In a subgroup of 10 patients, we also tested MEPs elicited by SICI, ICF, SICF, and input/output curves, before TBS. Between‐group analysis of variance showed that at all time points after iTBS MEPs increased, whereas after cTBS they decreased only in HS. In both subgroups tested, patients with predominant parkinsonian and cerebellar features, iTBS and cTBS left MEPs unchanged. MSA patients had reduced SICI, but normal ICF, SICF, and input/output curves. No correlation was found between patients' clinical features and responses to TBS and M1 excitability variables. These findings suggest impaired M1 plasticity in MSA. © 2013 International Parkinson and Movement Disorder Society 相似文献
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Murali Muniraju Muhammad Munir AravindhBabu R. Parthiban Ashley C. Banyard Jingyue Bao Zhiliang Wang Chrisostom Ayebazibwe Gelagay Ayelet Mehdi El Harrak Mana Mahapatra Geneviève Libeau Carrie Batten Satya Parida 《Emerging infectious diseases》2014,20(12):2023-2033
Despite safe and efficacious vaccines against peste des petits ruminants virus (PPRV), this virus has emerged as the cause of a highly contagious disease with serious economic consequences for small ruminant agriculture across Asia, the Middle East, and Africa. We used complete and partial genome sequences of all 4 lineages of the virus to investigate evolutionary and epidemiologic dynamics of PPRV. A Bayesian phylogenetic analysis of all PPRV lineages mapped the time to most recent common ancestor and initial divergence of PPRV to a lineage III isolate at the beginning of 20th century. A phylogeographic approach estimated the probability for root location of an ancestral PPRV and individual lineages as being Nigeria for PPRV, Senegal for lineage I, Nigeria/Ghana for lineage II, Sudan for lineage III, and India for lineage IV. Substitution rates are critical parameters for understanding virus evolution because restrictions in genetic variation can lead to lower adaptability and pathogenicity. 相似文献
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Kanwaljeet Garg Sumit Sinha Ashok Kumar Mahapatra Bhawani Shankar Sharma 《Child's nervous system》2014,30(5):919-923
Purpose
The purpose of the study was to analyze the surgical outcomes in children (≤18 years) with brachial plexus injury operated between April 2008 and March 2012 at our center.Methods
All children <18 years of age admitted to our center and surgically treated with a diagnosis of posttraumatic brachial plexus injury were included in the study. The demographic details of these patients were retrieved from the computerized database of our hospital. The results were analyzed in terms of the mode of injury, type of injury, surgical procedure performed, and motor recovery after the surgery (MRC Grading). Motor recovery with MRC >3/5 was termed as good outcome.Observations
A total of 33 patients were surgically treated. The mean age at presentation was 15.1 (range 4–18) years. Boys constituted 79 % (n?=?26) of our patient population. High-velocity injury was the commonest mode of injury. Panbrachial injury was the commonest seen in 82 % (n?=?27) of patients. Mean duration between injury and surgical intervention was 6 (range 2–13, SD?±?2.6) months. Majority of patients underwent neurotization procedure. Mean follow-up was 32 (range 6–51) months.Conclusions
High-velocity trauma is the most common mode on injury. Global palsy involving all the plexal elements was present in 82 % of the children. Neurotization was the most commonly performed surgical procedure. Good motor outcome (MRC grade ≥3/5) was seen in 62 % of patients. 相似文献37.
The aim of this case report was to present a case of multiple calcified tuberculous lymph nodes found on a panoramic radiograph coincidently diagnosed in an endodontic clinic. A detailed discussion on the differential diagnosis of similar such calcification found in the same region is also presented. A 14‐year‐old girl was referred to our department with the complaint of painless swelling in the left side of the lower jaw. Clinical and radiographical examinations were performed, leading to the initial diagnosis of chronic periapical abscess. The patient's medical history was re‐evaluated. Advanced imaging and excisional biopsy were performed in order to confirm the final diagnosis. Regarding the presenting signs and symptoms of bilateral carious mandibular molars, a periapical inflammatory process was considered in the provisional diagnosis. A thorough examination and investigations were suggestive of cervical tuberculous lymphadenitis (scrofula), and the patient underwent excision of the same. The clinician should consider the possibility of chronic granulomatous inflammatory lesions in the differential diagnosis of radiopaque lesions. 相似文献
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Amandeep Kumar Manish Singh Sharma Bhawani Shanker Sharma Rohit Bhatia Manmohan Singh Ajay Garg Rajinder Kumar Ashish Suri Poodipedi Sarat Chandra Shashank Sharad Kale Ashok Kumar Mahapatra 《Annals of Indian Academy of Neurology》2013,16(4):509-515