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51.
H.-J. Lee C.-C. Wu H.-M. Wu S.-C. Hung J.-F. Lirng C.-B. Luo F.-C. Chang W.-Y. Guo 《AJNR. American journal of neuroradiology》2015,36(3):508
BACKGROUND AND PURPOSE:Suprasellar papillary craniopharyngiomas and germ cell tumors in adults share some clinical and imaging similarities but have different therapeutic strategies and outcomes. This study aimed to evaluate the pretreatment diagnosis of these 2 tumors to improve the therapeutic outcome.MATERIALS AND METHODS:We retrospectively enrolled 18 adults with papillary craniopharyngiomas and 17 with germ cell tumors. The MR imaging findings were evaluated, including signal change and anatomic extension. The medical records were reviewed to collect clinical findings, management, and outcomes.RESULTS:The clinical findings of papillary craniopharyngiomas versus germ cell tumors were as follows: age: 46 ± 13.9 years versus 23 ± 7.1 years (P < .0001); diabetes insipidus: 2/18 (11%) versus 11/17 (65%) (P = .001); recurrence 13/16 (81%) versus 4/17 (24%) (P = .0031). The MR imaging findings of papillary craniopharyngiomas versus germ cell tumors were as follows—pituitary stalk thickening: 1.6 ± 0.4 mm versus 5.4 ± 4.2 mm (P < .0001); vertical infundibular extension: 1/18 (6%) versus 16/17 (94%) (P < .0001); sagittal spheric shape: 17/18 (94%) versus 1/17 (6%) (P < .0001); diffusion restriction: 1/17 (6%) versus 8/12 (67%) (P = .0009).CONCLUSIONS:Younger age, diabetes insipidus, MR imaging characteristics of restricted diffusion, and vertical infundibular extension favor the diagnosis of germ cell tumors. Spheric shape without infundibular infiltration provides clues to papillary craniopharyngiomas, which originate from the pars tuberalis and are located outside the third ventricle. We suggest that suprasellar germ cell tumor is possibly an intraventricular lesion. Appropriate treatment planning can be initiated according to the diagnosis and anatomic location.Except for pituitary macroadenoma, suprasellar tumors are infrequent in adult patients. Some of these suprasellar tumors have specific clinical and imaging features that make them straightforward to diagnose and subsequently manage. These classic features include a dural tail appearance in meningioma; young age; cysts and calcifications in adamantinomatous craniopharyngioma; homogeneous infiltrating mass of hypothalamic/optic pathway gliomas; a midline enhancing lesion in germ cell tumor (GCT); specific locations with signal similar to those of gray matter in hamartoma; and bright signals on DWI in epidermoids.1–3 However, some suprasellar tumors in adults can mimic each other in some clinical and imaging features, making pretreatment planning difficult.Papillary craniopharyngiomas (PCPs) and GCTs are 2 unusual suprasellar tumors in adults, with similar clinical and imaging findings in some aspects. Clinically, PCPs and GCTs mostly occur in young adults with visual impairment or pituitary axis dysfunction or diabetes insipidus. They commonly present as predominantly solid or mixed cysts and solid suprasellar lesions with contrast enhancement on MR imaging. However, the treatment and outcomes of both tumor types are quite different.2,4,5 Surgical resection not only is the main treatment of PCPs but also remarkably affects the outcome.6 By contrast, complete surgical resection is usually unnecessary in patients with germinoma. This radiosensitive tumor can be well-controlled by radiation therapy alone or combined with chemotherapy, even without a tissue diagnosis.7 The preoperative diagnosis of these 2 unusual suprasellar tumors in adults facilitates appropriate treatment planning and avoids associated surgical morbidity. We presumed that the distinct embryology and pathogenesis of the 2 tumors develop unique clinical and MR imaging characteristics. This study was designed to evaluate retrospectively the clinical and MR imaging findings of suprasellar papillary craniopharyngioma and germ cell tumors in adult patients, to obtain a pretreatment diagnosis. 相似文献
52.
53.
Wei-Ju Lee Shuu-Jiun Wang Li-Chi Hsu Jiing-Feng Lirng Chen-Hao Wu Jong-Ling Fuh 《Journal of neurology》2010,257(10):1675-1681
In this study, our objective was to identify the characteristic morphological features of brain MRI associated with a positive
cerebrospinal fluid (CSF) tap test in patients with idiopathic normal pressure hydrocephalus (iNPH). Patients diagnosed with
clinical suspected iNPH were evaluated. All patients underwent a mini-mental state examination, a brain MRI, and a CSF tap
test. The severities of clinical symptoms were rated before and after the CSF tap test. Characteristic brain MRI findings
including frontal convexity narrowing, parietal convexity narrowing, upward bowing of the corpus callosum, empty sella, narrowing
of the CSF space at the high convexity, marked dilatation of the Sylvian fissure, and disproportion between narrowing of the
CSF space at the high convexity and dilatation of the Sylvian fissure (“mismatch” sign) on T1-weighted or FLAIR image were
analyzed. Forty-three patients (33 males/ten females, mean age 76.9 ± 6.9 years) with possible iNPH participated in this study.
The presence versus absence of empty sella (52.4 vs. 14.3%, OR 6.6, 95% CI 1.5–29.4, p = 0.02) and “mismatch” sign (45.5 vs. 9.5%, OR 7.9, 95% CI 1.5–42.5, p = 0.02) were associated with positive CSF tap test responses. The sensitivity, specificity, positive predictive value, and
negative predictive value of the presence of either of these two MRI features in the prediction of CSF tap response were 72.7,
81, 80, and 73.9%, respectively. Specific brain MRI features can be used as markers for the identification of potential CSF
tap test responders in iNPH patients. These features may serve as supplemental evidence in the diagnosis of iNPH patients. 相似文献
54.
Chia-Wei Hung Shuu-Jiun Wang Shih-Pin Chen Jiing-Feng Lirng Jong-Ling Fuh 《Journal of neurology》2010,257(6):1045-1046
We report the case of a 77-year-old immuno-competent man who developed herpes zoster in the maxillary and mandibular branches
of the trigeminal nerve. Within 3 weeks, he developed ipsilateral peripheral facial palsy, hearing loss, vesicles over the
external auditory canal, and pain in the face and ear. A T2-weighted MRI of the brain revealed a hyper-intense lesion at the right medulla corresponding to the spinal trigeminal nucleus
and tract. Gadolinium enhancement was seen over the right facial nerve. These lesions suggest a possibility of transaxonal
spread of the varicella zoster virus between the trigeminal nerve, the facial nerve, and the spinal trigeminal nucleus and
tract. 相似文献
55.
Correlation of magnetic resonance images with neuropathology in acute Wernicke's encephalopathy 总被引:1,自引:0,他引:1
We correlated serial brain MRIs with neuropathological findings in a 16-year-old female whose autopsy was consistent with Wernicke's encephalopathy (WE). Diffusion-weighted imaging, diffusion coefficients mapping and neuropathology findings were suggested vasogenic edema in the periaqueductal and peri-the-fourth ventricular areas. This is the first documented case report to make this direct comparison. The characteristic WE changes in the mammillary body was also correlated with the findings of MRI with contrast enhancement. Bilateral cortical lesions revealed by MRI were atypical and rare in WE and were not evidenced by pathological changes. 相似文献
56.
Eleven patients with primary thunderclap headache (TCH) were treated with oral nimodipine 30 to 60 mg every 4 hours or IV nimodipine 0.5 to 2 mg/h if the oral regimen failed or images showed cerebral vasospasm. With oral nimodipine, headache did not recur in the nine patients without vasospasm. IV nimodipine was given in two patients with vasospasm, including one who developed ischemic stroke. Nimodipine may be effective for TCH. Vasospasm may warrant IV nimodipine. 相似文献
57.
Teng MM Wei CJ Wei LC Luo CB Lirng JF Chang FC Liu CL Chang CY 《AJNR. American journal of neuroradiology》2003,24(9):1893-1900
BACKGROUND AND PURPOSE: Percutaneous vertebroplasty is known for its pain-relieving effect. Our purpose was to evaluate its effect on the kyphosis angle, wedge angle, and height of the fractured vertebral body. METHODS: We reviewed digital radiographs of 73 vertebral bodies in 53 patients before and after vertebroplasty. We measured the spinal kyphosis angle and the wedge angle of the fractured vertebral body. Ratios of the height of the anterior border, center, and posterior borders of the collapsed vertebra to the height at the posterior border of an adjacent normal vertebral body were measured. Gain from vertebroplasty and the restoration percentage (gain divided by loss) were calculated for each parameter. RESULTS:The kyphosis angle, wedge angle, anterior height, center height, and posterior height significantly improved after vertebroplasty. The mean reduction in the kyphosis angle was 4.3 degrees, and the wedge-angle reduction was 7.4 degrees. The mean wedge-angle reduction in fractured vertebral bodies containing gas was 10.2 degrees. Restoration percentages for the kyphosis angle and wedge angle were 19% and 44%, respectively. Gain in the height of the fractured vertebral bodies was 16.7% for the anterior border, 14% for the center, and 7% for the posterior border. Restoration percentages for the height of the vertebral body were 29% for the anterior border and 27% for the center. CONCLUSION: Vertebroplasty increases the height of the fractured vertebra and reduces the wedge and kyphosis angles. These effects are most remarkable in fractured vertebra containing gas. 相似文献
58.
The authors measured the average diameter of bilateral superior ophthalmic veins (SOV) in 13 patients with spontaneous intracranial hypotension (SIH) on contrast-enhanced, coronal, T1-weighted MRI. Compared with sex- and age-matched neurology inpatients with normal CSF pressure, the SIH group had a smaller SOV diameter (0.90 vs 1.85 mm, p < 0.001), which partly reversed after treatment (1.09 vs 0.90 mm, p = 0.045, n = 7). Collapsed SOV might provide an additional MRI finding for SIH. 相似文献
59.
BACKGROUND: Idiopathic hypertrophic cranial pachymeningitis (IHCP) is an uncommon disorder due to localized or diffuse thickening of the dura mater. While headache is the most common manifestation, the clinical characteristics of the headache in IHCP have not been well characterized. METHODS: From 1996 to 2002, 6 consecutive patients with IHCP presenting with headache were reviewed (3 women, 3 men; mean age: 49 years). Diagnosis was based on characteristic neuroimaging findings and the exclusion of secondary causes of cranial pachymeningitis. This study reported the headache characteristics, neuroimaging features, and longitudinal follow-up. RESULTS: Chronic daily headache, especially chronic migraine, was the most common headache pattern observed (4/6 patients). Lateralization of headache location appeared to correlate with the distribution of the hypertrophied dural lesions. Diagnostic delay was due to failure to evaluate with gadolinium-enhanced MRI. After treatment, headache (5/6, 83%) and neurologic deficits (2/3, 67%) improved in most patients; however, follow-up MRIs (n = 5) showed deterioration in 3 patients. CONCLUSION: The headache of IHCP is typically a chronic daily headache, often resembling chronic migraine. Correspondingly, IHCP should be considered in the differential diagnosis of refractory chronic daily headache, with or without associated cranial neuropathy or other associated neurologic deficits. The typical imaging finding on gadolinium-enhanced MRI is localized or diffuse pachymeningitis and failure to order a gadolinium-enhanced MRI is the primary reason for delayed diagnosis. Despite symptomatic improvement on longitudinal follow-up, the MRI abnormalities may not improve in parallel with the clinical symptoms. 相似文献
60.
We report on a 22-year-old assistant cook, presenting with seizures evoked by immersing his right hand into hot water of 40-46 degrees C. His seizure pattern consisted of either simple partial seizures of a tingling sensation arising in the right hand and marching to the right shoulder or a similar attack evolving to a complex partial seizure. Video-EEG monitoring recorded habitual seizures originating from the left centro-temporo-parietal region, compatible with lesions seen on brain magnetic resonance imaging. He responded well to antiepileptic drug treatment and wearing gloves while working in the kitchen. In this patient, hot water of 40-46 degrees C could maximally stimulate skin warm thermoreceptors in the right hand whereby afferent impulses subsequently activated the epileptogenic focus, adjacent to or in the sensory cortex, and elicited seizures. 相似文献