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Rechtsanwalt Dr. iur. Gert Riedel LL.M.Eur. 《MedR Medizinrecht》2009,27(2):83-85
Ohne Zusammenfassung 相似文献
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目的:探讨马利兰导致继发再障的原因及安全使用马利兰的方法。方法:通过6例因慢粒而使用马利兰治疗后导致继发再障临床资料分析。结果:马利兰导致继发再障与药物剂量、用药时间及个体敏感性有关。结论:遵循小剂量、长疗程的原则使用马利兰治疗慢粒,可减少继发再障的发生。 相似文献
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Factors influencing women to undergo screening mammography 总被引:2,自引:0,他引:2
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MSTM Almeida SCB Lima LL Carvalho JVM Almeida LG Santos JRA Rolim TE Rocha 《Journal of cutaneous pathology》2010,37(11):1170-1173
Systemic sclerosis (SSc) is an autoimmune systemic disease characterized by small vessel involvement that leads to tissue ischemia and fibroblast stimulation resulting in accumulation of collagen (fibrosis) in the skin and internal organs. Lipomembranous panniculitis is a peculiar type of fat necrosis and has been reported with clinical conditions, commonly with peripheral vascular diseases. We describe a case of a 43‐year‐old woman with SSc manifestations, who presented with black scaly skin plaques, associated with thickening of the subcutaneous fat tissue, on the lateral surface of her thighs, her calves, gluteal area and lower abdomen. Biopsy revealed lipomembranous panniculitis. Lipomembranous changes have been seen in connective tissue disorders such as lupus profundus, morphea, systemic sclerosis and panniculitis associated with dermatomyositis, but rarely in thighs, calves, gluteal area and lower abdomen. Almeida MSTM, Lima SCB, Carvalho LL, Almeida JVM, Santos LG, Rolim JRA, Rocha TE. Panniculitis–An unusual cutaneous manifestation of systemic sclerosis. 相似文献
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Transfusions to group O subjects of 2 units of red cells enzymatically converted from group B to group O 总被引:6,自引:0,他引:6
BACKGROUND: It has previously been shown that full-unit (200 mL) transfusions of red cells (RBCs) enzymatically converted from group B to group O by treatment with alpha-galactosidase (ECO RBCs) are both safe and efficacious for normal group O or A subjects. STUDY DESIGN AND METHODS: The present study describes the results of a comprehensive clinical and serologic assessment of 2-unit (400 mL) ECO RBC transfusions to each of four normal group O subjects (after each had donated 1 unit of whole blood). RESULTS: Clinical (hematologic tests, chemistry analysis, urinalysis) and serologic analyses revealed no evidence of immediate or delayed transfusion reaction, despite a threefold to fivefold elevation in pre-existing anti-B antiglobulin titer. 51Cr-labeled ECO RBCs were administered to one of the four subjects to allow direct measurement of ECO RBC survival in the circulation, which indicated that it was normal (24-hour survival, 95%; t1/2, 29.5 days). The observed increases in hemoglobin (by 1.3 +/− 0.4 g/dL [13 +/− 4 g/L]) and hematocrit (by 3.2 +/− 0.8% [0.032 +/− 0.008]) in transfused subjects provide further evidence of the efficacy of these cells in vivo. CONCLUSION: These results extend those observed in our earlier 1-unit transfusion studies and suggest that ECO RBCs pose little risk and will be useful in transfusion medicine. 相似文献
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