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Oida T Mimatsu K Kano H Kawasaki A Kuboi Y Fukino N Kida K Amano S 《Hepato-gastroenterology》2012,59(118):1832-1834
Background/Aims: Colon interposition is the most commonly used method of esophageal reconstruction when the stomach cannot be used; however, this method may cause surgical complications such as anastomotic leakage and sepsis due to colon necrosis. Therefore, many surgeons use a retrosternal or subcutaneous route because it is easier to manage the subcutaneous drainage when anastomotic leakage occurs. However, some researchers have reported that the posterior mediastinal route provides better long-term functional outcomes after surgery than the anterior mediastinal route. Thus, in this study, we compared these reconstruction routes used for colon interposition, with or without the supercharge technique, in patients with a history of distal gastrectomy, who have undergone colon interposition after esophagectomy. Methodology: We retrospectively studied 30 patients who underwent esophagectomy with colon interposition. These patients were divided into 2 groups based on the reconstruction route: the anterior mediastinal or subcutaneous route (A group), or the posterior mediastinal route (R group). Results: Anastomotic leakages were observed in 4 patients (26.7%) in the A group and in 1 patient (6.7%) in the R group. Conclusions: Ischemia is not always the result of arterial failure, but may also originate from venous blood flow impairment due to injury or distortion of veins. 相似文献
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Maki Nishimura Junko Kohara Jun Hiasa Yoshikage Muroi Naoaki Yokoyama Katsuya Kida Xuenan Xuan Hidefumi Furuoka Yoshifumi Nishikawa 《Clinical and Vaccine Immunology : CVI》2013,20(2):309-312
Histopathology and quantitative PCR (qPCR) were used to determine the tissue distribution of Neospora caninum in calves at 80 days postinfection. Our findings revealed that the most appropriate brain areas for researching N. caninum pathogenesis were the amygdala and hippocampus for qPCR and the corpus striatum and diencephalon for histopathology. 相似文献
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Fujii W Kohno M Ishino H Nakabayashi A Fujioka K Kida T Nagahara H Murakami K Nakamura K Seno T Yamamoto A Kawahito Y 《Modern rheumatology / the Japan Rheumatism Association》2012,22(4):630-634
We report a case of rheumatoid vasculitis (RV) that responded well to abatacept, a cytotoxic T lymphocyte-associated antigen 4 (CTLA4)-immunoglobulin fusion protein. A 38-year-old woman developed RV despite treatment with methotrexate and tumor necrosis factor (TNF) inhibitors. The effects of steroid therapy, immunoabsorption plasmapheresis, and interleukin-6 inhibitor were insufficient, however, administration of abatacept rapidly improved her clinical symptoms with almost normalization of the immunological findings. This is the first published case report of the successful treatment of RV with abatacept. 相似文献
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Ishii T Hagiwara K Ikeda S Arai T Mieno MN Kumasaka T Muramatsu M Sawabe M Gemma A Kida K 《COPD》2012,9(4):409-416
Surfactant protein D (SFTPD) is a lung-specific anti-inflammatory factor that antagonizes inflammation by inhibiting oxidative stress and stimulating innate immunity. Variations in SFTPA2 and SFTPB, genes for other surfactant proteins, have been associated with lung cancer. We therefore investigated associations between SFTPD variations and lung cancer as well as emphysema and interstitial pneumonia, which are characterized by chronic inflammation from which lung cancer often arises. DNA from 1342 autopsy samples, including those from 140 subjects with lung cancer, was investigated. The single nucleotide polymorphism (SNP) rs721917, which results in methionine being exchanged for threonine at amino acid 11 (the Met11Thr variation), tended to be associated with emphysema and was associated with interstitial pneumonia and lung cancer. A haplotype analysis revealed that the haplotypes associated with emphysema and lung cancer differed from that associated with interstitial pneumonia, suggesting a differential role for SFTPD in the development of these diseases. A mediating analysis did not reveal a mediating effect exerted by emphysema or interstitial pneumonia on lung cancer. Our results suggested that SFTPD plays a role in the development of lung cancer and that the role for lung cancer may differ from that for interstitial pneumonia. 相似文献
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Yoshikazu Kida Toru Morihara Ken-Ichi Matsuda Yoshiteru Kajikawa Hisakazu Tachiiri Yoshio Iwata Kazuhide Sawamura Atsuhiko Yoshida Yasushi Oshima Takumi Ikeda Hiroyoshi Fujiwara Mitsuhiro Kawata Toshikazu Kubo 《Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]》2013,22(2):197-205
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Yukiko Hasuike Takanori Nagai Soshi Yorifuji Saiko Tanaka Ayako Matsumoto Mana Yahiro Shoji Kaibe Aritoshi Kida Masanori Tokuyama Yasuyuki Nagasawa Yoshinaga Otaki Takahiro Kuragano Takeshi Nakanishi 《Clinical and experimental nephrology》2013,17(3):424-430