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排序方式: 共有1677条查询结果,搜索用时 31 毫秒
121.
Keisuke Hamada Tomoko Tanaka Kazuhiro Yamamoto Eiichi Sennari Masahide Tahara Yoshizumi Yamauchi Manabu Takei Osamu Yoshii Harumichi Madokoro Tomoe Maemura Hiroko Suzumiya Sachiyo Saito Takahiro Okishima Yuzi Matsuoka Yuichi Sato Shozo Ohdo Kunio Hayakawa Nobuaki Kida Yatsuki Aratake Sachiya Ohtaki 《Pediatrics international》1981,23(3):391-392
122.
Role of selectins on IgE-mediated skin reaction 总被引:3,自引:0,他引:3
Wada Y Kuzuhara A Hanamura M Kida R Yoshinaka T Saito T 《British journal of pharmacology》2000,131(8):1531-1536
Selectins play an important role on leukocytes infiltration into inflammatory tissues. To understand the role of selectins, we investigated the effects of selectin-IgG chimeras and anti selectin antibodies on the murine IgE-mediated skin inflammation model. Biphasic skin reactions were induced by intradermal challenge with ovalbumin (OA) to ears of actively sensitized mice. This reaction was characterized by immediate and late phase responses observed as which were induced via a rapid increase in capillary permeability and leukocyte infiltration, respectively. The expression of E-selectin mRNA was significantly increased to reach its highest level at 2 h after OA challenge. E-, P-, and L-selectin-IgG chimeras inhibited the late phase responses, i.e. ear swelling, neutrophil infiltration and eosinophil infiltration at 24 h after OA challenge in a dose-dependent manner at dose range of 0.1 - 10 mg kg(-1), i.v. Antiselectin antibodies did not inhibit the increase of ear swelling. But anti E- and P-selectin antibodies significantly inhibited neutrophil infiltration and eosinophil infiltration. These results indicate that selectins play an important role on the late phase response of the murine IgE-mediated skin inflammation model by mediating inflammatory cell adhesion to endothelium. 相似文献
123.
M Kida K Tanaka F Hattori S Kondou W Harada A Takagi K Itou H Matsumoto K Kojima K Taniyama 《Nihon Shokakibyo Gakkai zasshi》1990,87(5):1154-1159
We histologically compared 3 types of adenoma and cancer of the large intestine using 620 adenoma specimens (509 Is type lesions, 83 Ip type lesions, and 28 flat type lesions) and 113 specimens of early stage cancer (51 Is type lesions, 39 Ip type lesions, and 23 flat type lesions) obtained during the past 5-year period at our department. More than 90% of the Is and Ip type polyps were adenoma or carcinoma in adenoma while 25.5% of the flat elevations were m or sm carcinoma. Flat elevations even less than 10 mm in diameter were frequently carcinomas (26.3%) compared with the other types (both Is and Ip types, 6.7%), and all of those 10 mm or more in size were carcinomas. The distribution of the flat type early cancers in the large intestine was similar to that of advanced cancer with high percentages of carcinoma at each site compared with the other types. These results suggest that the carcinogenesis and progression of flat type early stage cancer differ from those of the other types. 相似文献
124.
Noriyuki Tohnosu MD Akihiko Takeda Teruo Kouzu Shoichi Onoda Kaichi Isono 《Surgery today》1987,17(6):528-532
A 65-year-old man with spontaneous rupture of the esophagus survived with a direct suture of the esophagus 15 hours after
the onset of symptoms. Endoscopic examination of the esophagus was especially of great help in determining the surgical procedure
in this patient, and we want to stress the importance of prompt diagnosis and immediate surgery for this disease. 相似文献
125.
126.
Kimiichi Uno Keiko Imazeki Noboru Arimizu Takamasa Ryu Kaichi Isono Yusuke Kitakata Hirobumi Kohen Sadao Uematsu 《Annals of nuclear medicine》1987,1(1):27-31
We report our experiences with the combined use of indium-111 labeled leukocyte imaging (In-III WBC scan.), computed tomography (CT) and ultrasonography (US) for evaluation of suspected postoperative infection or abscess, and discuss the complementary roles of these modalities. Postoperative abscesses or infections were diagnosed in 9 of 20 patients. All patients were correctly diagnosed by In-111 WBC imaging and 4 patients could not be diagnosed by US because of bowel gas. One false-positive CT examination and another artifact on CT images due to respiratory movements were obtained. The three modalities were found to be complementary: CT and US were efficient imaging methods for diagnosis and treatment of abscess. In-111 WBC imaging could estimate the activity of inflammation. 相似文献
127.
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130.
Change in cytokeratin 19 fragment level according to the severity of pulmonary alveolar proteinosis.
Y Minakata Y Kida H Nakanishi T Nishimoto S Yukawa 《Internal medicine (Tokyo, Japan)》2001,40(10):1024-1027
A 48-year-old man was diagnosed with primary alveolar proteinosis (PAP). Whole lung lavage was performed for treatment, and the opacity on his chest X-ray completely disappeared. The value of cytokeratin 19 fragment (CYFRA) in the serum was high at the beginning, decreased after lung lavage, and became elevated again when the disease recurred 7 months later. As PAP is thought to be a problem of surfactant secreted from type II pneumocytes, and a cytokeratin is present in the alveolar epithelial tissue, the value of serum CYFRA might be related to the severity of PAP. 相似文献