全文获取类型
收费全文 | 1445111篇 |
免费 | 119412篇 |
国内免费 | 6615篇 |
专业分类
耳鼻咽喉 | 18510篇 |
儿科学 | 46339篇 |
妇产科学 | 38830篇 |
基础医学 | 198463篇 |
口腔科学 | 40203篇 |
临床医学 | 127507篇 |
内科学 | 305271篇 |
皮肤病学 | 35364篇 |
神经病学 | 119044篇 |
特种医学 | 57929篇 |
外国民族医学 | 275篇 |
外科学 | 223629篇 |
综合类 | 32105篇 |
现状与发展 | 2篇 |
一般理论 | 444篇 |
预防医学 | 117344篇 |
眼科学 | 30520篇 |
药学 | 101251篇 |
5篇 | |
中国医学 | 2732篇 |
肿瘤学 | 75371篇 |
出版年
2019年 | 11524篇 |
2018年 | 17677篇 |
2017年 | 13146篇 |
2016年 | 15083篇 |
2015年 | 16839篇 |
2014年 | 22842篇 |
2013年 | 34217篇 |
2012年 | 44258篇 |
2011年 | 47398篇 |
2010年 | 28639篇 |
2009年 | 26871篇 |
2008年 | 43185篇 |
2007年 | 46048篇 |
2006年 | 46620篇 |
2005年 | 45169篇 |
2004年 | 42612篇 |
2003年 | 41278篇 |
2002年 | 39002篇 |
2001年 | 69047篇 |
2000年 | 71359篇 |
1999年 | 59184篇 |
1998年 | 17128篇 |
1997年 | 15276篇 |
1996年 | 16256篇 |
1995年 | 16428篇 |
1994年 | 15245篇 |
1993年 | 14284篇 |
1992年 | 48104篇 |
1991年 | 46600篇 |
1990年 | 44720篇 |
1989年 | 42437篇 |
1988年 | 39258篇 |
1987年 | 38592篇 |
1986年 | 36383篇 |
1985年 | 35074篇 |
1984年 | 26684篇 |
1983年 | 22349篇 |
1982年 | 13963篇 |
1981年 | 12559篇 |
1980年 | 11822篇 |
1979年 | 23831篇 |
1978年 | 17237篇 |
1977年 | 14549篇 |
1976年 | 13349篇 |
1975年 | 13953篇 |
1974年 | 16364篇 |
1973年 | 15698篇 |
1972年 | 14428篇 |
1971年 | 13302篇 |
1970年 | 12138篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Are Dermatophytid Reactions in Patients with Kerion Celsi Much More Common Than Previously Thought? A Prospective Study 下载免费PDF全文
Dermatophytid reactions are secondary eruptions in response to dermatophytosis. Only a few cases demonstrating an association between dermatophytid reactions and tinea capitis have been reported. Dermatophytid reactions were evaluated in patients diagnosed with kerion celsi. Patients admitted to the dermatology clinic of Van Regional Training and Research Hospital between November 22, 2012, and July 1, 2013, diagnosed with kerion celsi were evaluated for dermatophytid reactions. Six girls (32%) and 13 boys (68%) were included in this study. Dermatophytid reactions were detected in 13 of the 19 patients (68%). Seven patients (36.84%) had eczematous patches or plaques and three (15.8%) had papules. Eczematous lesions, papules, and pustules were noted in two patients (10.5%) and one (5.3%) had signs of an angioedema‐like reaction. Dermatophytid reactions in all patients were observed before the initiation of therapy. According to our clinical experiences, dermatophytid reactions in patients with kerion celsi were more common than reported. Eczematous scaly patches or plaques were the most frequently seen forms of dermatophytid in patients with kerion celsi. Dermatophytid reactions may occur before or after initiation of systemic antifungal therapy. Recognition of this reaction is important so that dermatophytids can be distinguished from drug reactions and the decision can be made whether to continue or to stop the systemic antifungal treatment. 相似文献
102.
103.
104.
105.
Tselios Konstantinos Yap Kristy Su-Ying Pakchotanon Rattapol Polachek Ari Su Jiandong Urowitz Murray B. Gladman Dafna D. 《Clinical rheumatology》2019,38(1):269-269
Clinical Rheumatology - Prof. Ari Polachek on of the author of the published version of this article missed to add his second affiliation which is the Department of Rheumatology, Tel Aviv Sourasky... 相似文献
106.
107.
108.
109.
Widely Metastatic Squamous Cell Carcinoma Originating from Malignant Transformation of Hypertrophic Lichen Planus in a 24‐Year‐Old Woman: Case Report and Review of the Literature 下载免费PDF全文
Lana X. Tong B.A. Matthew J. Weinstock M.D. Reed Drews M.D. Caroline C. Kim M.D. 《Pediatric dermatology》2015,32(3):e98-e101
Hypertrophic lichen planus (HLP) is a T‐cell‐mediated process typically presenting with hypertrophic or verrucous plaques on the lower limbs. We report the case of a 24‐year‐old woman with a history of HLP since age 3 years presenting with rapid malignant transformation of one lesion into a large squamous cell carcinoma (SCC). Subsequent examination revealed progressive, widespread metastatic involvement, and the patient ultimately died from her disease. SCC associated with HLP is rare, with a review of the literature revealing fewer than 50 cases. This case highlights the need to be aware of suspicious changes in HLP and to educate patients as to when to be reevaluated. 相似文献
110.
Melatonin reduces oxidative stress and improves vascular function in pulmonary hypertensive newborn sheep 下载免费PDF全文
Flavio Torres Alejandro González‐Candia Camilo Montt Germán Ebensperger Magdalena Chubretovic María Serón‐Ferré Roberto V. Reyes Aníbal J. Llanos Emilio A. Herrera 《Journal of pineal research》2015,58(3):362-373
Pulmonary hypertension of the newborn (PHN) constitutes a critical condition with severe cardiovascular and neurological consequences. One of its main causes is hypoxia during gestation, and thus, it is a public health concern in populations living above 2500 m. Although some mechanisms are recognized, the pathophysiological facts that lead to PHN are not fully understood, which explains the lack of an effective treatment. Oxidative stress is one of the proposed mechanisms inducing pulmonary vascular dysfunction and PHN. Therefore, we assessed whether melatonin, a potent antioxidant, improves pulmonary vascular function. Twelve newborn sheep were gestated, born, and raised at 3600 meters. At 3 days old, lambs were catheterized and daily cardiovascular measurements were recorded. Lambs were divided into two groups, one received daily vehicle as control and another received daily melatonin (1 mg/kg/d), for 8 days. At 11 days old, lung tissue and small pulmonary arteries (SPA) were collected. Melatonin decreased pulmonary pressure and resistance for the first 3 days of treatment. Further, melatonin significantly improved the vasodilator function of SPA, enhancing the endothelial‐ and muscular‐dependent pathways. This was associated with an enhanced nitric oxide‐dependent and nitric oxide independent vasodilator components and with increased nitric oxide bioavailability in lung tissue. Further, melatonin reduced the pulmonary oxidative stress markers and increased enzymatic and nonenzymatic antioxidant capacity. Finally, these effects were associated with an increase of lumen diameter and a mild decrease in the wall of the pulmonary arteries. These outcomes support the use of melatonin as an adjuvant in the treatment for PHN. 相似文献