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991.
Dong Ha Kim Kapsok Li Seong Jun Seo Sun Jin Jo Hyeon Woo Yim Churl Min Kim Kyu Han Kim Do Won Kim Moon-Bum Kim Jin Woo Kim Young Suck Ro Young Lip Park Chun Wook Park Seung-Chul Lee Sang Hyun Cho 《Journal of Korean medical science》2012,27(11):1327-1332
Quantification of quality of life (QOL) related to disease severity is important in patients with atopic dermatitis (AD), because the assessment provides additional information to the traditional objective clinical scoring systems. To document the impact of AD on QOL for both children and adults as well as to quantify the relationship with disease severity, QOL assessments were performed over a 6-month period on 415 patients with AD. A questionnaire derived from the Infants'' Dermatitis Quality of Life Index (IDQOL), the Children''s Dermatology Life Quality Index (CDLQI) and the Dermatology Life Quality Index (DLQI) was used to determine the QOL for 71 infants, 197 children and 147 adults, respectively. To measure AD severity, both the Rajka & Langeland scoring system and the Scoring of Atopic Dermatitis (SCORAD) index were used. The mean scores were as follows: 7.7 ± 5.5 for IDQOL, 6.6 ± 6.3 for CDLQI, and 10.7 ± 7.9 for DLQI. In conclusion, these QOL scores are correlated with AD severity scores as estimated by the Rajka & Langeland severity score and the SCORAD. The outcome of the QOL instruments in this study demonstrates that atopic dermatitis of both children and adults affects their QOL. 相似文献
992.
C. Moreno Alarcón P.A. López González P. López Cubillana G. Doñate Iñíguez J.C. Ruiz Morcillo E.H. Olarte Barragán G. Gómez Gómez 《Actas urologicas espa?olas》2010,34(6):531-536
ObjectivesTo evaluate the incidence of minor complications that rarely need treatment (haematuria, hematospermia and rectal bleeding) and major complications (fever and shock) in patients undergoing transrectal biopsy of the prostate and to identify risk factors.Patients and methodsWe present an analitic and prospective study where we evaluated 146 patients subjected to transrectal biopsy of the prostate from December 2007 to September 2008. Complications rates and variables were analized.ResultsEight pacients (5,5%) suffered fever and seven (4,8%) of them were admitted. One of the pacients (0,7%) suffered shock. The median of time between biopsy and fever was 3.5 days (1–10 days). Haematuria and hematospermia were more frequent in patients younger than 65 years (p<0.05) and fever and sepsis were more frequent in patients with prostate volume smaller than 55 mL (p<0.05).ConclusionsThe complications of the transrectal biopsy of the prostate are frequent, autolimited and they rarely suppose a health hazard for the patients. The most frequent are haematuria and hemospermia, specially in younger patients, whereas infectious complications are rarer and in our study are more frequent in patients with smaller prostates.We must take into account that the information to the patient is very important after a prostate biopsy, so we can avoid useless consultations (for example with haematuria) and it will enable to identify important signs like fever earlier. 相似文献
993.
M. Gümüşel M. Özdemir İ. Mevlitoğlu S. Bodur 《Journal of the European Academy of Dermatology and Venereology》2011,25(9):1080-1084
Background Treatment of psoriatic nail is difficult. Objective The aim of this study was to evaluate and compare the efficacy and safety of methotrexate and cyclosporine in psoriatic nail. Methods Thirty‐seven psoriatic patients with nail involvement were randomized to treatment with methotrexate (initial dose, 15 mg per week) or cyclosporine (initial dose, 5 mg per kg of bodyweight per day) for 24 weeks. The primary outcome was the Nail Psoriasis Severity Index (NAPSI). The Psoriasis Area and Severity Index (PASI), doctor and patient global score were also measured. The scores were determined by a blinded observer. Results Seventeen patients completed the study in each group. The mean percentages of reduction of the NAPSI score after methotrexate and cyclosporine treatments were 43.3% and 37.2%, respectively. No significant differences between the treatment groups was found for in the NAPSI, PASI, physician’s and patient’s global score at the end of the study period. The methotrexate group showed a significant improvement in nail matrix scores and the cyclosporine group in nail bed score. Conclusion Moderate effectiveness on psoriatic nail was found in the two treatment agents and there were no significant differences in efficacy between the groups. A significant improvement was detected in methotrexate group for the nail matrix findings, and in cyclosporine group for the nail bed findings. 相似文献
994.
Murat Yiğiter Abdullah Yildiz Akgün Oral Ahmet Bedii Salman 《International urology and nephrology》2010,42(4):985-990
Purpose
The aim of this study was to compare the complication rates of the single flap and double flaps versus flapless procedure in the tubularized incised plate urethroplasty. 相似文献995.
996.
997.
Jae Hun Jun Ho Youn Kim Han Jin Jung Weon Ju Lee Seok-Jong Lee Do Won Kim Moon Bum Kim Byung Soo Kim 《ANNALS OF DERMATOLOGY》2011,23(3):342-347
Parry-Romberg syndrome (PRS) is a relatively rare degenerative disorder that is poorly understood. PRS is characterized by slowly progressing atrophy affecting one side of the face, and is frequently associated with localized scleroderma, especially linear scleroderma, which is known as en coup de sabre. This is a report of the author''s experiences with PRS accompanying en coup de sabre, and a review of the ongoing considerable debate associated with these two entities. Case 1 was a 37-year-old woman who had right hemifacial atrophy with unilateral en coup de sabre for seven years. Fat grafting to her atrophic lip had been conducted, and steroid injection had been performed on the indurated plaque of the forehead. Case 2 was a 29-year-old woman who had suffered from right hemifacial atrophy and bilateral en coup de sabre for 18 years. Surgical corrections such as scapular osteocutaneous flap and mandible/maxilla distraction showed unsatisfying results. 相似文献
998.
Begül Yağci MD Özge Salor MD Bilgehan Yalçin MD Figen Gürakan MD Şafak Güçer MD Münevver Büyükpamukçu MD 《Pediatric blood & cancer》2009,52(7):870-871
Gaucher disease (GD) is a lysosomal storage disease characterized by deficiency of β‐glucocerebrosidase, which results in accumulation of glucocerebroside in reticuloendothelial system, bone marrow infiltration, progressive hepatosplenomegaly, and skeletal complications. Herein we report a 5‐year‐old female with GD receiving enzyme replacement therapy who had giant mesenteric lymphadenopathies. Pediatr Blood Cancer 2009;52:870–871. © 2009 Wiley‐Liss, Inc. 相似文献
999.
Figen Esin Kayhan Meliha Koldemir Penbe Cagatay Cavlan Ciftci Belgin Susleyici-Duman 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2013,7(1):12-16
AimsOur aim was to evaluate the effects of endothelial nitric oxide synthase (eNOS) E298D polymorphism in obesity variables and essential hypertension (eHT) development risk. The genotype frequencies of E298D polymorphism in eHT patients and non-hypertensive (non-HT) controls (proven to have normal coronaries angiographically) were analyzed for their association with demographic and obesity related data of the eHT patients and controls.Materials and methodseNOS gene E298D genotypes were determined with qPCR.ResultsThe eNOS E298D polymorphism frequencies for 298E/E, 298E/D and 298D/D genotypes were respectively as 41.1%, 44.6%, 14.3% in subjects eHT and 52.8%, 38.9%, 8.3% in the non-HT groups. The combined E298D homozygous polymorphic and heterozygous genotypes were found to have a decreasing effect on serum total-cholesterol levels in comparison to wild-type genotypes in eHT patients but not controls.ConclusionsOur results support the idea that, the eNOS E298D polymorphism, which is not associated with hypertension, may increase the risk of hypertension when associated with high serum total-cholesterol levels. 相似文献
1000.
Hüseyin Per Mehmet CanpolatHakan Gümüş Hatice Gamze PoyrazoğluAli Yıkılmaz Sarper KaraküçükHakkı Doğan Sefer Kumandaş 《Brain & development》2013
Objective: Pseudotumor cerebri (PTC) is a clinical condition characterized by signs and symptoms of increased intracranial pressure, such as headache and papilledema. Our aim was to investigate the etiological and clinical features of pseudotumor cerebri (PTC) in children. Materials and method: We performed a comprehensive analysis of epidemiology, diagnostic work-up, therapy, and clinical follow-up in 42 consecutive patients. Results: Totally 42 patients diagnosed with PTC [27 (64.3%) females and 15 (35.7%) males] were included in the study. The average age of the symptoms onset was 10.79 ± 3.43 years (range from 12 months to 17 years). Obesity was found in eleven (26.2%) of them. Two of the patients had familial mediterranean fever, two of them had posttraumatic PTC. The following diseases were one patient, respectively; mycophenolate mofetil-induced PTC, hypervitaminosis A induced PTC, corticosteroid induced withdrawal due to nephritic syndrome, use of oral contraceptives, Guillain–Barre syndrome, urinary tract infection, varicella-zoster virus infection and dural venous sinus thrombosis associated with otitis media. The most common symptom was headache, recorded in 76.2% of the patients. All patients were treated medically. Three patients in our group also required a ventriculoperitoneal shunt. Conclusion: Pseudotumor cerebri is an avoidable cause of visual loss, both in adults and children. Pre-pubertal obese girls are more common. Medical therapy appeared to be successful in treating pediatric PTC in most patients. Nevertheless, despite adequate treatment, children can rarely experience loss of visual field and acuity; thus, prompt diagnosis and management are important. 相似文献