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Adrian S. Fairey Wassim Kassouf Eric Estey Simon Tanguay Ricardo Rendon David Bell Jonathan Izawa Joseph Chin Anil Kapoor Edward Matsumoto Peter Black Alan So Jean‐Baptiste Lattouf Fred Saad Darrel Drachenberg Ilias Cagiannos Louis Lacombe Yves Fradet Niels‐Erik B. Jacobsen 《BJU international》2013,112(6):791-797
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The clinical syndrome of parkinsonism was identified in ancient India even before the period of Christ and was treated methodically. The earliest reference to bradykinesia dates to 600 bc . Evidences prove that as early as 300 bc , Charaka proposed a coherent picture of parkinsonism by describing tremor, rigidity, bradykinesia, and gait disturbances as its components. The scenario was further developed by Madhava, Vagbhata, and Dalhana all through history. The 15th‐century classic “Bhasava rajyam” introduced the term kampavata, which may be regarded as an ayurvedic analogue of parkinsonism. The pathogenesis of kampavata centered on the concept of imbalance in the vata factor, which controls psychomotor activities. The essential element in therapy was the administration of powdered seed of Mucuna pruriens, or atmagupta, which as per reports, contains 4%?6% of levodopa. In addition to proving the existence and identification of parkinsonism in ancient India, the study points to the significance of ancient Indian Sanskrit works in medical history. © 2013 Movement Disorder Society 相似文献
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Bhilare Neha V. Dhaneshwar Suneela S. Mahadik Kakasaheb R. Dasgupta Arunava Zende Tejal Kapoor Siddhart 《Pharmaceutical Chemistry Journal》2020,54(7):678-688
Pharmaceutical Chemistry Journal - The long-course treatment of tuberculosis with isoniazid (INH) leads to hazardous side effects on liver and poor patient compliance. To overcome these toxic... 相似文献
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Merchant Rutvij Goldin Aleah Manjanatha Deepa Harter Claire Chandler Judy Lipp Amanda Nguyen Theresa Naslund John A. 《The Psychiatric quarterly》2022,93(2):613-625
Psychiatric Quarterly - This study investigated whether with disruptions in care due to the COVID-19 pandemic, persons who self-identified as living with a mental health condition increased their... 相似文献
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Tina Sara Verghese Rita Champaneria Dharmesh S Kapoor Pallavi Manish Latthe 《International urogynecology journal》2016,27(10):1459-1467
Introduction
There is conflicting evidence on whether mediolateral episiotomy (MLE) reduces the risk of obstetric anal sphincter injuries (OASI) in spontaneous vaginal deliveries (SVD).Objectives
A systematic review was undertaken to compare rates of OASI amongst women who had undergone mediolateral episiotomy versus those who did not.Methods
?Search strategy
Electronic searches were performed in literature databases: CINAHL, Cochrane, EMBASE, Medline and MIDIRS from database inception to July 2015. Studies were eligible if MLE was compared to spontaneous tears and if OASI was the outcome of interest.Two reviewers independently selected and extracted data on study characteristics, quality and results. We computed events of OASI in those who did and did not have an episiotomy from individual studies and pooled these results in a meta-analysis where possible.Main results
Of the 2090 citations, 16 were included in the review. All were non-randomised, population based or retrospective cohort studies. There was great variation in quality amongst these studies. Data from 7 studies was used for meta-analysis. On collating data from these studies where the majority of women (636755/651114) were nulliparous, MLE reduced the risk of OASI (RR 0.67 95 % CI 0.49-0.92) in vaginal delivery.Conclusion
The pooled analysis of a large number of women undergoing vaginal birth, most of who were nulliparous, indicates that MLE has a beneficial effect in prevention of OASI. An accurately given MLE might have a role in reducing OASI and should not be withheld, especially in nulliparous women. Caution is advised as the data is from non-randomised studies.140.