全文获取类型
收费全文 | 22112篇 |
免费 | 1963篇 |
国内免费 | 49篇 |
专业分类
耳鼻咽喉 | 246篇 |
儿科学 | 725篇 |
妇产科学 | 402篇 |
基础医学 | 3055篇 |
口腔科学 | 350篇 |
临床医学 | 2356篇 |
内科学 | 4472篇 |
皮肤病学 | 326篇 |
神经病学 | 1919篇 |
特种医学 | 876篇 |
外国民族医学 | 3篇 |
外科学 | 2734篇 |
综合类 | 536篇 |
一般理论 | 14篇 |
预防医学 | 2255篇 |
眼科学 | 744篇 |
药学 | 1617篇 |
中国医学 | 31篇 |
肿瘤学 | 1463篇 |
出版年
2022年 | 147篇 |
2021年 | 322篇 |
2020年 | 244篇 |
2019年 | 371篇 |
2018年 | 385篇 |
2017年 | 292篇 |
2016年 | 342篇 |
2015年 | 415篇 |
2014年 | 594篇 |
2013年 | 876篇 |
2012年 | 1246篇 |
2011年 | 1329篇 |
2010年 | 666篇 |
2009年 | 723篇 |
2008年 | 1113篇 |
2007年 | 1280篇 |
2006年 | 1198篇 |
2005年 | 1219篇 |
2004年 | 1176篇 |
2003年 | 1005篇 |
2002年 | 1010篇 |
2001年 | 461篇 |
2000年 | 487篇 |
1999年 | 497篇 |
1998年 | 377篇 |
1997年 | 271篇 |
1996年 | 289篇 |
1995年 | 243篇 |
1994年 | 218篇 |
1993年 | 195篇 |
1992年 | 318篇 |
1991年 | 314篇 |
1990年 | 307篇 |
1989年 | 330篇 |
1988年 | 289篇 |
1987年 | 270篇 |
1986年 | 294篇 |
1985年 | 246篇 |
1984年 | 222篇 |
1983年 | 173篇 |
1982年 | 170篇 |
1981年 | 143篇 |
1980年 | 136篇 |
1979年 | 202篇 |
1978年 | 152篇 |
1977年 | 125篇 |
1976年 | 109篇 |
1975年 | 111篇 |
1974年 | 115篇 |
1973年 | 135篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
For many parents stopping life-sustaining medical treatment on their dying infant is psychologically impossible. Dostoevsky's insights into human behavior, particularly the fact that individuals do not want the anxiety and guilt associated with responsibility for making difficult decisions, might change the way physicians approach parents for permission to withdraw life-prolonging medical interventions on dying infants. 相似文献
12.
AIMS: To establish all-cause and cause-specific death rates, and risk factors for mortality in insulin-treated diabetic individuals living in the province of Canterbury, New Zealand. METHODS: Insulin-treated diabetic subjects (n = 995) on the Canterbury Diabetes Registry were followed up over 15 years and vital status determined. Death rates were standardized and hazard regression was used to model the effects of demographic covariates on relative survival time. RESULTS: There were 419 deaths in 11 226.3 person-years of follow-up with a standardized mortality ratio (SMR) of 2.0 (95% confidence interval (CI) 1.8-2.2). Relative mortality was greatest for the group aged 0-29 years (SMR 3.0 (95% CI 2.4-3.7)). After controlling for diabetes duration and gender, a 10-year increment in age of onset was associated with a 33% decrease in relative hazard (95% CI 29-36%), indicating that excess mortality due to diabetes declines with rising age of onset. After controlling for age of onset and gender, each 10-year increment in duration of diabetes is associated with a 26% decrease in relative hazard (95% CI 24-29%), indicating that with longer survival the mortality hazard approaches the general population hazard. Relative mortalities were increased for cardiovascular, renal and respiratory disease, but not malignancy. Relative mortality from acute metabolic complications was increased in the subgroup with age of onset of diabetes < 30 years and requiring insulin within 1 year of diagnosis. CONCLUSIONS: Mortality rates are high for insulin-treated diabetic individuals relative to the general population. 相似文献
13.
14.
15.
David A. Hughes Graham C. Smith Joyce E. Davidson Anna V. Murphy T. James Beattie 《Pediatric nephrology (Berlin, Germany)》1996,10(4):445-447
. Neutrophil-mediated tissue damage has been implicated in the pathogenesis of diarrhoea-associated haemolytic uraemic syndrome
(D+ HUS). This study evaluates priming and activation of the neutrophil oxidative burst in D+ HUS using chemiluminescent techniques.
Peripheral blood neutrophils from 11 children with acute D+ HUS were examined. No difference was found in the oxidative burst
of neutrophils from patients and controls. Serum elastase levels were measured in 8 patients and found to be significantly
elevated. Although elastase results suggest neutrophil activation, chemiluminescence studies do not confirm this in the peripheral
blood neutrophil. This does not support a significant role for circulating agents in priming and activating the peripheral
blood neutrophil.
Received August 17, 1995; received in revised form and accepted November 27, 1995 相似文献
16.
Graham M. O'Hanlon Margaret B. Lowrie 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1995,103(2):243-250
Disruption of neuromuscular contact by nerve-crush during the early postnatal period causes increased activity and abnormal reflex responses in affected motoneurons, but such changes are not found after nerve-crush in adult animals. We found previously that neonatally lesioned cells develop an abnormal dendritic field, which may explain the functional changes. Here we have studied the dendritic morphology of the same motoneuron pool after nerve-crush at maturity in order to correlate the observed alterations in morphology with physiological findings. One to two months after sciatic nerve-crush in adult animals, motoneurons supplying the extensor hallucis longus muscles of the rat were retrogradely labelled with cholera toxin subunit-B conjugated to horseradish peroxidase. The dendritic tree of labelled cells was then analysed. Following adult nerve-crush, the dendritic tree of the motoneurons was smaller but did not display the localised increase in dendritic density seen after neonatal nerve-crush. These findings support the view that such specific morphological changes contribute to the physiological abnormalities seen only after neonatal nerve injury. 相似文献
17.
D Y Graham 《Mayo Clinic proceedings. Mayo Clinic》1988,63(12):1258-1260
Occurrence of C. pylori infection of mucosa outside of the stomach might provide an ideal opportunity to examine C. pylori-mucosal interactions apart from the effects of acid and pepsin. Techniques previously used to examine Barrett's epithelium (for example, special mucin stains or scanning and transmission electron microscopy) might be particularly useful for exploration of new associations and formulation of new hypotheses. Whether C. pylori has a role in development of Barrett's ulcer or adenocarcinoma as a complication of Barrett's esophagus remains unanswered. Most of the current data about C. pylori are primarily observational; further studies are needed for clarification of important microbegut interactions. 相似文献
18.
19.
Glenn Roberts John Somers Jocelyn Dawe Rowena Passy Carly Mays Graham Carr David Shiers Jo Smith 《Early intervention in psychiatry》2007,1(2):168-176
Aims: On the Edge is a mental health education programme designed to support early intervention by increasing knowledge and understanding of early psychosis, reducing the stigma associated with mental health issues and improving awareness of avenues of help. The target audience was young people aged 14–22 years in schools and colleges. Methods: An interactive drama programme was developed through collaborative working across psychiatry, applied drama and those with direct experience of psychosis. A national tour engaged 2500 students in 71 performances that took place in 51 schools and colleges. The programme was evaluated against its aims with data collected both during and after the tour. Results: Quantitative and qualitative evaluation found significant gains with respect to all three aims. Thirty‐one schools developed supportive links with local mental health services. Conclusions: This programme shows the value and effectiveness of delivering health education on early psychosis through the medium of applied drama, and offers a model for a programme that can be incorporated into early intervention services. Lessons learned through delivering this programme are a valuable contribution towards future developments of mental health education programmes for schools. 相似文献
20.