全文获取类型
收费全文 | 1982篇 |
免费 | 147篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 90篇 |
妇产科学 | 17篇 |
基础医学 | 267篇 |
口腔科学 | 22篇 |
临床医学 | 177篇 |
内科学 | 448篇 |
皮肤病学 | 30篇 |
神经病学 | 176篇 |
特种医学 | 152篇 |
外国民族医学 | 1篇 |
外科学 | 250篇 |
综合类 | 120篇 |
预防医学 | 88篇 |
眼科学 | 5篇 |
药学 | 107篇 |
中国医学 | 8篇 |
肿瘤学 | 175篇 |
出版年
2022年 | 11篇 |
2021年 | 24篇 |
2020年 | 21篇 |
2019年 | 19篇 |
2018年 | 24篇 |
2017年 | 24篇 |
2016年 | 24篇 |
2015年 | 46篇 |
2014年 | 55篇 |
2013年 | 54篇 |
2012年 | 92篇 |
2011年 | 80篇 |
2010年 | 68篇 |
2009年 | 76篇 |
2008年 | 102篇 |
2007年 | 77篇 |
2006年 | 78篇 |
2005年 | 75篇 |
2004年 | 75篇 |
2003年 | 72篇 |
2002年 | 54篇 |
2001年 | 65篇 |
2000年 | 65篇 |
1999年 | 75篇 |
1998年 | 65篇 |
1997年 | 50篇 |
1996年 | 44篇 |
1995年 | 33篇 |
1994年 | 49篇 |
1993年 | 32篇 |
1992年 | 35篇 |
1991年 | 29篇 |
1990年 | 31篇 |
1989年 | 45篇 |
1988年 | 40篇 |
1987年 | 46篇 |
1986年 | 36篇 |
1985年 | 37篇 |
1984年 | 14篇 |
1983年 | 16篇 |
1982年 | 17篇 |
1981年 | 10篇 |
1978年 | 14篇 |
1977年 | 13篇 |
1976年 | 14篇 |
1975年 | 14篇 |
1974年 | 15篇 |
1970年 | 9篇 |
1968年 | 11篇 |
1966年 | 8篇 |
排序方式: 共有2146条查询结果,搜索用时 187 毫秒
11.
Serge Evrard Yves Bécouarn René Brunet Marianne Fonck Caroline Larrue Simone Mathoulin-Pélissier 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(1):41-44
BACKGROUND AND AIMS: The aim of this work was to test the feasibility of using a bipolar low thermal acting system inducing collagenic sealing but not protein coagulation to secure hepatic parenchyma cutting. MATERIALS AND METHODS: Thirty consecutive hepatectomies were carried out using kellyclasy plus ligatures and clips (controls), while the following 50 hepatectomies used kellyclasy plus bipolar vessels sealer (BVS). Blood loss, duration of hepatic pedicle clamping, length of hospital stay, and complications were recorded. RESULTS: There was no statistically significant difference in blood loss and duration of clamping between controls and BVS. Specific complications (9/21 in the control group vs 1/49 for the BVS group, p<0.00045) and length of hospital stay (14 days in the control group vs 11 days in the BVS group, p<0.014) were statistically lower in BVS group than in the controls, mainly due to prevention of bile duct leakages. CONCLUSIONS: Our data suggest that BVS may be particularly efficient to achieve bilistasis leading to the highest level of safety in performing hepatectomies. Further studies are now needed to confirm its superiority on the classical biliary ducts occlusion techniques. 相似文献
12.
E Rosset C Brunet B Meunier PA Marie V DiMarino M Argème J Farisse 《Surgical and radiologic anatomy : SRA》1995,17(1):1-5
We studied specimens from 50 cadavers (27 men and 23 women) to obtain anatomical data concerning the liver and its attachments. The results allowed us to develop a polyglactin perihepatic prosthesis for compression of the injured liver. The falciform ligament and a narrowing of the hepatic parenchyma at this level allow attachment of the prosthesis. Separate prostheses were designed for each lobe. Clinical use has demonstrated that our prosthesis can be used to achieve effective control of haemorrhage and bile leakage.
Etude anatomique du foie. Développement d'une prothèse péri-hépatique
Résumé Sur une série de 50 pièces anatomiques d'adultes (27 hommes, 23 femmes), l'étude morphométrique du foie, de ses attaches dorsales et leurs variations a permis la confection d'une prothèse périhépatique en polyglactine adaptable à chaque lobe et fixée grâce à des artifices anatomiques. Celle-ci assure une compression efficace du parenchyme lésé et donc une hémostase et une bilistase correctes. Le ligament falciforme et le rétrecissement du parenchyme hépatique à son niveau assurent le maintien de la prothèse. Un exemplaire a été réalisé pour chaque lobe.相似文献
13.
M Braun F Boman J M Hascoet P Chastagner A Brunet C Simon 《Journal of neuroradiology. Journal de neuroradiologie》1992,19(1):68-74
The authors report two cases of brain tissue heterotopia in the nasopharynx, without other malformations and, in one of the cases, with a persistent craniopharyngeal canal opening onto the heterotopia. This exceptional malformation is very similar to brain heterotopia in the nose, or "nasal glioma", which is more frequent and less diversified at histology. The malformation is revealed by obstruction of the pharynx with respiratory distress immediately after birth or during the first weeks of life. Total surgical excision provides cure without sequelae. The diagnosis is based on histology. MRI is essential to the diagnostic and pretherapeutic evaluation, notably to avoid missing an ectopic hypophysis, but it is insufficient to diagnose a sphenoidal meningoencephalocele. 相似文献
14.
Evaluation of a new enzyme-linked immunosorbent assay test for rotavirus antigen in faeces 总被引:6,自引:0,他引:6
下载免费PDF全文
![点击此处可从《Journal of clinical pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
A new commercial test for the diagnosis of rotavirus gastroenteritis was assessed. With some modifications it compared favourably with electron microscopy and immunofluorescence. 相似文献
15.
Competitive control of the self-renewing T cell repertoire 总被引:1,自引:0,他引:1
We develop a mathematical model for the self-renewing part of the T cell
repertoire. Assuming that self-renewing T cells have to be stimulated by
immunogenic MHC-peptide complexes presented on the surfaces of
antigen-presenting cells, we derive a model of T cell growth in which
competition for MHC-peptide complexes limits T cell clone sizes and
regulates the total number of self-renewing T cells in the animal. We show
that for a sufficient diversity and/or degree of cross-reactivity, the
total T cell number hardly depends upon the diversity of the T cell
repertoire or the diversity of the set of presented peptides. Conversely,
for repertoires of lower diversity and/or cross-reactivity, steady-state
total T cell numbers may be limited by the diversity of the T cells. This
provides a possible explanation for the limited repertoire expansion in
some, but not all, mouse T cell re-constitution experiments. We suggest
that the competitive interactions described by our model underlie the
normal T cells numbers observed in transgenic mice, germ-free mice and
various knockout mice.
相似文献
16.
Pattyn A Simplicio N van Doorninck JH Goridis C Guillemot F Brunet JF 《Nature neuroscience》2004,7(6):589-595
17.
18.
19.
F Sabatier F Dignat-George J L Mge C Brunet D Raoult J Sampol 《Clinical and Vaccine Immunology : CVI》1997,4(1):89-92
Valvular endocarditis is the most serious complication of chronic Q fever, an infectious disease due to Coxiella burnetii. Although its pathogenesis is poorly understood, the role of the immune system has been evoked. The aim of this study was to investigate lymphocyte subsets in the peripheral blood of infected patients by analyzing the distribution of T- and B-lymphocyte subsets. Since various infectious diseases have been found to be associated with modified antigen expression, we also measured the antigen density of the main lymphocyte markers by quantitative flow cytometry. The absolute values of CD3+ T cells and CD19+ B cells were lower in infected subjects than in controls. The decrease in the CD4+ T-cell count was more pronounced than that in the CD8+ T-cell count, leading to a significantly lower CD4/CD8 ratio in patients. The decreases in CD4+ T cells and CD19+ B cells were correlated with levels of C. burnetii-specific immunoglobulin G, showing that CD4+ lymphopenia is related to the activity of chronic Q fever. Quantitation of antigen expression on lymphocytes showed that CD3, CD4, CD8, and CD19 were expressed similarly in patients and controls. In contrast, CD2 and CD11a expression levels, which are both related to naive and memory phenotypes, were modified in patients. The study of CD45RO and CD45RA expression by CD4+ T cells provided evidence that lymphopenia preferentially affected unprimed lymphocytes. 相似文献
20.
V Di Marino M Argème Ch Brunet R Coppens J Bonnoit 《Surgical and radiologic anatomy : SRA》1987,9(1):51-62
Summary The dissection of. 48 cadaveric specimens has been compared with operative findings for a review of the shape, size and site of this gland in the adult. The structure of the thymic compartment and the relations of the thymus, particularly with the vessels of the superior mediastinum and the base of the neck, were studied. The relative positions of the inferior parathyroid glands and the thymus were identified, with respect to the influence of this topography on the surgery of these glands. The arterial suply to the thymus, which is still very abundant in the adult, presupposes a functional organ whose physiologic involution is slow.
Etude macroscopique du thymus de l'adulte
Résumé La dissection de 48 pièces cadavériques, confrontée à des données opératoires, permet de rappeler la forme, la taille et la situation de cette glande chez l'adulte. La constitution de la loge thymique puis les rapports du thymus avec, en particulier, les vaisseaux du médiastin supérieur et la base du cou sont étudiés. Les positions respectives des glandes parathyroïdes inférieures et du thymus avec l'incidence de cette topographie dans la chirurgie de ces glandes, sont précisées. La vascularisation artérielle de la glande, encore très riche chez l'adulte est en faveur d'un organe fonctionnel dont l'involution physiologique est lente.相似文献